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Partition coefficient n-octanol/water is the most commonly used parameter for describing lipophilicity. The aim of this study was the usefulness of high performance liquid chromatography (HPLC) for determination of log Pow for chlorothalonil based on OECD 117: OECD Guidelines For The Testing of Chemicals – Partition Coefficient (n-octanol/water), High Performance Liquid Chromatography (HPLC) Method (2004). As reference substances: aniline, benzonitrile, nitrobenzene, chlorobenzene, toluene, 1,4-dichlorobenzene, 1,2,4-trichlorobenzene were selected. The dead time was measured by using methanol as an unretained substance. The obtained by HPLC technique value of log Pow for chlorothalonil amounted to 2.93, and was comparable to literature data 2.92. The results revealed the usefulness of presented method in registration studies on chlorothalonil.
In this paper we discussed using chromatographic techniques such as gas chromatography (GC and GC/MS), liquid chromatography (HPLC/DAD and RR-HPLC) and planar chromatography (TLC and HPTLC), also near infrared spectroscopy (NIR) in identification analysis of plant protection products falsifications. Examples are given of typical falsifications and methods of their detection.
Quality control of the products used in plant protection is provided mainly by producers of pesticides. According to EU regulations it is obligatory for countries to have an independent quality control system for pesticides present on the market. An independent system is very important for the appropriate functioning of the domestic plant protection. It ensures discipline towards producers and retailers. In Poland such monitoring has a long tradition. Post registration quality determination are provided by the Institute of Plant Protection, samples are taken by the inspectors from the Plant Protection and Seeds Inspectorate through the whole country. The 400 annual limit includes some samples analyzed as a result of a claim or a low suit for compensation due to improper effects or lack of effectiveness. Biologically active substance (a.s.) is the most important quality parameter. Many samples show discrepancies (either lower or higher results), however significantly defected is only about 1% of determinations. In cases of significant quality flaws the Plant Protection and Seeds Inspectorate may issue an administrative decision to withdraw a batch of a product from distribution and use. It is crucial to posses technical capabilities to provide quality testing for all pesticides that are currently or were in the past in use in Poland. Particularly, in cases of claims, recalls and law suits.
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