Wyniki wyszukiwania

1

"Świat RNA"

100%

Szweykowska-Kulinska Z.

Biotechnologia

|

2003

|

nr 2

2

Dojrzewanie roslinnych tyrozynowych transferowych RNA zawierajacych intron

100%

Szweykowska-Kulinska Z.

Seria Biologiczna. Uniwersytet im. Adama Mickiewicza w Poznaniu

|

1995

|

nr 54

97

3

Biologiczne funkcje zmodyfikowanych nukleozydow w transferowych RNA

100%

Szweykowska-Kulinska Z.

Postępy Biochemii

|

1993

|

tom 39

|

nr 2

84-91

4

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

The old and new RNA world

100%

Szweykowska-Kulinska Z.

Acta Societatis Botanicorum Poloniae

|

2014

|

tom 83

|

nr 4

Among the numerous hypotheses offering a scenario for the origin of life on Earth, the one called “The RNA World” has gained the most attention. According to this hypothesis RNA acted as a genetic information storage material, as a catalyst of all metabolic reactions, and as a regulator of all processes in the primordial world. Various experiments show that RNA molecules could have been synthesized abiotically, with the potential to mediate a whole repertoire of metabolic reactions. Ribozymes carrying out aminoacyl-tRNA reactions have been found in SELEX (systematic evolution of ligands by exponential enrichment) approaches and the development of a ribosome from a RNA-built protoribosome is easy to imagine. Transfer RNA aminoacylation, protoribosome origin, and the availability of amino acids on early Earth allowed the genetic code to evolve. Encoded proteins most likely stabilized RNA molecules and were able to create channels across membranes. In the modern cell, DNA replaced RNA as the main depositor of genetic information and proteins carry out almost all metabolic reactions. However, RNA is still playing versatile, crucial roles in the cell. Apart from its classical functions in the cell, a huge small RNA world is controlling gene expression, chromatin condensation, response to environmental cues, and protecting the cell against the invasion of various nucleic acids forms. Long non-coding RNAs act as crucial gene expression regulators. Riboswitches act at the level of transcription, splicing or translation and mediate feedback regulation on biosynthesis and transport of the ligand they sense. Alternative splicing generates genetic variability and increases the protein repertoire in response to developmental or environmental changes. All these regulatory functions are essential in shaping cell plasticity in the changing milieu. Recent discoveries of new, unexpected and important functions of RNA molecules support the hypothesis that we live in a New RNA World.

5

Two intron-containing pre-tRNAsTyr from Triticum aestivum are efficiently processed and spliced in homologous cell-free extract

100%

Szweykowska-Kulinska Z.

Acta Biochimica Polonica

|

1992

|

tom 39

|

nr 3

Two wheat pre-tRNAsTyr containing introns and flanks are accurately and efficiently spliced in homologous wheat germ S23 extract. The initiation and termination sites upon in vitro transcription in HeLu cell extract have been estimated for both pre-tRNAs.

6

Regulation of gene expression by small RNAs in eukaryots

100%

Szweykowska-Kulinska Z.

Biological Letters

|

2005

|

tom 42

|

nr 2 Spec.Vol.

7

Biogenesis and function of plant microRNAs

75%

Szweykowska-Kulinska Z.

Acta Biochimica Polonica

|

2018

|

tom 65

|

nr S2

8

Application of molecular techniques to taxonomic studies

63%

Lesicki A., Szweykowska-Kulinska Z.

Folia Malacologica

|

1999

|

tom 07

|

nr 4

9

O inteinach: ich budowie, ewolucji i zastosowaniach

63%

Sawczak M., Szweykowska-Kulinska Z.

Postępy Biochemii

|

2004

|

tom 50

|

nr 1

69-81

10

Geny transferowych RNA: ich organizacja i ekspresja

63%

Szweykowska-Kulinska Z., Augustyniak J.

Postępy Biochemii

|

1987

|

tom 33

|

nr 2-3

11

Regulacja alternatywnego splicingu

63%

Szczesniak M., Szweykowska-Kulinska Z.

Postępy Biologii Komórki

|

2009

|

tom 36

|

nr 1

23-35

63%

Karwowska U., Szweykowska-Kulinska Z.

Biological Bulletin of Poznań

|

1998

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tom 35

|

nr 1

18

New intron-containing human tRNA Leu genes

63%

Karwowska U., Szweykowska-Kulinska Z.

Acta Biochimica Polonica

|

1997

|

tom 44

|

nr 4

Three new human nuclear tRNA(Leu) genes have been isolated and sequenced using the PCR technique. Two of them represent genes containing a CAA anticodon and both contain introns of 22 nucleotides in length but differing in sequence. Intron-containing prolongated anticodon stems can be folded into a secondary structure similar to that of yeast pre-tRNA(Leu). The evolutionary conserved secondary structure suggests the same role of intron sequences in the human and yeast pre-tRNA(Leu) maturation pathway.

19

In vitro collection of Polish liverwort species of the genus Pellia Raddi, 1820 [Hepaticae, Metzgeriales]

63%

Fiedorow P., Szweykowska-Kulinska Z.

Biological Bulletin of Poznań

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1998

|

tom 35

|

nr 1

20

The influence of polyamines on polymerase chain reaction [PCR]

63%

Fiedorow P., Szweykowska-Kulinska Z.

Acta Biochimica Polonica

|

1997

|

tom 44

|

nr 1

Twelve different polyamines from three functional groups have been tested for their influence on polymerase chain reaction (PCR). Using crude total DNA from the liverwort Pellia borealis we have found that tri- and tetra mines can strongly improve the efficiency of PCR.

Ograniczanie wyników

"Świat RNA"

Dojrzewanie roslinnych tyrozynowych transferowych RNA zawierajacych intron

Biologiczne funkcje zmodyfikowanych nukleozydow w transferowych RNA

The old and new RNA world

Two intron-containing pre-tRNAsTyr from Triticum aestivum are efficiently processed and spliced in homologous cell-free extract

Regulation of gene expression by small RNAs in eukaryots

Biogenesis and function of plant microRNAs

Application of molecular techniques to taxonomic studies

O inteinach: ich budowie, ewolucji i zastosowaniach