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This work presents the results of an experimental study and of computer simulations concerning electric interactions in the surface layer of egg yolk lecithin (EYL) liposome membranes. The surface layer is formed by EYL polar heads, which possess features of electric dipoles, and positive charged polar heads belonging to admixtures of quaternary ammonium salts (AS). The results of the experimental study are in good agreement with the ones of the computer simulations. It was found that fluidity of the membranes, at a given concentration of AS, obtains the extremal (minimal) value. Similarly, the binding energy of the dipoles-positive charges system behaves like that in computer simulations. Moreover, the locations of the fluidity extremum and those of the binding energy depend on the charge of the AS polar heads as well as on the degree of electric interactions screening by the environment. At a certain optimal value of the screening coefficient, the energy of the system is the lowest (the most negative) and together with the rise in AS charge, the minimum of the energy moves towards its higher concentrations.
Our work studied the effect of selected organometallic chloride compounds on electrical properties of membrane, in the form of hydrophilic filters impregnated with lauric acid. The presence of the compounds in the membrane surroundings induced a quick increase of the membrane voltage that decreased more slowly after reaching the maximum value, and stabilized after a lapse of a specified period of time. In the case of triphenyltin, the voltage changed direction during measurement and stabilized in negative values. Based on the results obtained, it was found that the effectiveness of the interaction of the compounds studied with the membrane is highest in the case of triphenyltin chloride. The change of voltage polarization in the case of triphenyltin may denote that chlorine ions released in the dissociation process penetrated the other side the membrane.
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