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Wykorzystanie wiadomości SMS do badania opinii klientów 60+ sektora opieki zdrowotnej

100%
Smiatacz K., Blachnio A.
Marketing i Rynek
|
2015
|
tom 22
|
nr 08
2
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Wellbeing and older adults in primary health care in Poland

100%
Blachnio A., Bulinski L.
Annals of Agricultural and Environmental Medicine
|
2019
|
tom 26
|
nr 1
3
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

An evaluation of life satisfaction and health – Quality of life of senior citizens

81%
Ziolkowski A., Blachnio A., Pachalska M.
Annals of Agricultural and Environmental Medicine
|
2015
|
tom 22
|
nr 1
4

The effect of fat rich diet on ceramide level and enzymes activity of ceramide metabolism in the rat skeletal muscle

81%
Blachnio A., Baranowski M., Zabielski P., Gorski J.
Acta Biochimica Polonica
|
2006
|
tom 53
|
nr Supplement 1
5
Content available remote

PPARalpha agonist induces the accumulation of ceramide in the heart of rats fed high-fat diet

80%
Baranowski M., Blachnio A., Zabielski P., Gorski J.
Journal of Physiology and Pharmacology
|
2007
|
tom 58
|
nr 1
It was shown that high-fat feeding of mice with cardiac-specific overexpression of peroxisome proliferator-activated receptor (PPAR) alpha but not wild type animals leads to the accumulation of ceramide (an important mediator of lipotoxicity) in the heart [Finck et al. 2003 Proc Natl Acad Sci USA]. To investigate the mechanism of this phenomenon we examined the effects of PPARalpha activation on ceramide metabolism in the myocardium. Male Wistar rats were fed either a standard chow or a high-fat diet. Each group was divided into two subgroups: control and treated with selective PPARalpha activator – WY-14643. In the rats fed on the standard diet WY-14643 did not affect the myocardial content of sphingomyelin and ceramide but reduced the content of sphinganine and sphingosine. It also inhibited the activity of neutral sphingomyelinase and increased the activity of acid sphingomyelinase, whereas the activity of ceramidases and serine palmitoyltransferase (SPT) remained stable. High-fat diet itself did not affect the content of the examined sphingolipids. However, it reduced the activity of sphingomyelinases and ceramidases having no effect on the activity of SPT. Administration of WY-14643 to this group significantly increased the content of myocardial free palmitate, ceramide, sphingomyelin and the activity of SPT. Our results demonstrated that PPARalpha activation modulates myocardial ceramide metabolism and leads to the accumulation of ceramide in the heart of the high-fat fed rats due to its increased synthesis de novo.
6

Influence of sport activity on satisfaction with life and sense of coherence among physically disabled people

71%
Ziolkowski A., Zubrzycki I., Blachnio A., Zaranska B., Moska W.
Baltic Journal of Health and Physical Activity. The Journal of Gdansk University of Physical Education and Sport
|
2016
|
tom 08
|
nr 4
Background: The study discusses the differences in the levels of satisfaction withlife (SWL) and a sense of coherence (SOC) in disabled sedentary people, disabled persons performing leisure sports and competitive disabled athletes. Material/Methods: The data were analyzed using analysis of covariance, Pearson-correlation and a linear regression. Results: The results indicate that sport elicits an insignificant increase in SWL and SOC. SOC correlates with SWL in sedentary disabled and competitive disabled athletes. In disabled persons performing leisure sports, the level of physical activity must be tuned in order to elicit a congruent increase in SWL and SOC. Conclusions: Continued research on sport and wellness interventions for the individuals with disabilities is recommended. A critical emerging issue is to develop and promote evidence-based sport and wellness programs for physically disabled people in the Republic of Poland.
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