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Overexpression of human osteopontin increases cell proliferation and migration in human embryo kidney-293 cells

100%

Liu Y. J., Zhang D.-Q., Sui X.-M., Tian W.

Cellular and Molecular Biology Letters

2009

tom 14

nr 4

670-678

Malignant tumors are characterized by dysregulated cell growth and the metastasis of secondary tumors. Numerous studies have documented that osteopontin (OPN) plays a key role in regulating tumor progression and metastasis. Here, we show that the overexpression of OPN in human embryo kidney-293 cells significantly increases both the level of cell proliferation, by provoking the G1/S transition, and the level of cell migration in vitro. These findings suggest that augmented OPN contributes to cell growth and motility. Inhibiting OPN or the pathway it stimulates may therefore represent a novel approach for the treatment of primary tumors and associated metastases.

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Free chlorine loss during spraying of membraneless acidic electrolyzed water and its antimicrobial effect on airborne bacteria from poultry house

64%

Zhao Y., Xin H., Zhao D., Zheng W., Tian W., Ma H., Liu K., Hu H., Wang T., Soupir M.

Annals of Agricultural and Environmental Medicine

2014

tom 21

nr 2

Ograniczanie wyników

1 Annals of Agricultural and Environmental Medicine

1 Cellular and Molecular Biology Letters

2 Tian W.

1 Hu H.

1 Liu K.

1 Liu Y. J.

1 Ma H.

1 Soupir M.

1 Sui X.-M.

1 Wang T.

1 Xin H.

1 Zhang D.-Q.

1 Zhao D.

1 Zhao Y.

1 Zheng W.

1 2014

1 2009

Wyniki wyszukiwania

Overexpression of human osteopontin increases cell proliferation and migration in human embryo kidney-293 cells

Free chlorine loss during spraying of membraneless acidic electrolyzed water and its antimicrobial effect on airborne bacteria from poultry house