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1

Zachowawcze leczenie zespolu endometritis-pyometra u suk z zastosowaniem aglepristonu

100%
Domoslawska A., Janowski T.
Medycyna Weterynaryjna
|
2008
|
tom 64
|
nr 09
1146-1149
The aim of the study was to evaluate the efficacy of aglepristone - a progesterone receptor blocker - in the treatment of endometritis-pyometra complex (EPC) in bitches. 12 bitches of pure and mixed breeds between 2 and 13 years of age with EPC were examined. All animals were treated according to the same pattern: aglepristone (Alizine, Virbac®) was administered at the dose of 0.33 ml/kg, s.c. on days 1, 2, 7, and 14. Additionally, the antibiotic amoxycyline (Clamoxyl, Pfizer®) was administered at the dose of 1 ml/10 kg, s.c. every 48 hours for 10 days. A complete puss mass elimination, uterus involution and improvement of clinical state were observed after 3 weeks of treatment. Progesterone concentration, that was highly increased at the beginning of treatment, decreased to low levels during its first week. The leukocyte count (WBC), alkaline phosphatase (AP), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) exceeded normal values before and in the first days of treatment. These parameters improved to normal values after the first week of treatment. The recurrence of EPC was not observed in any bitch during the next 2 years. Three bitches were mated in next heats but did not get pregnant. In the present study the antigestagens therapy proved highly effective: clinical recovery and the recurrence of normal haematological and biochemical counts were observed.
2

Improvement of sperm motility within one month under selenium and vitamin E supplementation in four infertile dogs with low selenium status

81%
Domoslawska A., Zdunczyk S., Janowski T.
Journal of Veterinary Research
|
2019
|
tom 63
|
nr 2
3
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Progesterone level does not distinguish the different course of canine ovulation determined by ultrasonography

81%
Domoslawska A., Jurczak A., Janowski T.
Polish Journal of Veterinary Sciences
|
2014
|
tom 17
|
nr 2
The aim of this study was to compare progesterone concentrations in bitches during ovulation with a different course of follicular collapse as determined by ultrasonography. The study was conducted on 36 animals of different breeds, from 2 to 7 years old, and from 2 to 44 kg of body weight. Ultrasound examinations of ovaries were conducted in the peri-ovulatory period until ovulation was detected. Based on USG scans the animals were divided into two groups: group A with fast follicular collapse within 1 day, and group B with gradual follicular collapse within 2-3 days. Progesterone measurements were performed in both groups on the day when the beginning of ovulation was diagnosed by USG. Follicular collapse in group A was observed in 27.8% of animals (n=10) and in group B in 72.2% (n=26). There were no statistical differences (p<0.05) in progesterone concentrations between groups A and B (6.68 ± 0.92 ng/ml and 6.81 ± 0.57 ng/ml respectively). From 31 bred bitches (natural mating or insemination) pregnancy was confirmed in 29 females (93.5%). These results provide information about the sufficient stability of progesterone concentration during ovulation regardless of the follicular collapse speed. Ultrasonography during the peri-ovulatory period combined with progesterone measurements allows progress in ovulation management.
4
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Oral folic acid supplementation decreases palate and/or lip cleft occurrence in Pug and Chihuahua puppies and elevates folic acid blood levels in pregnant bitches

81%
Domoslawska A., Jurczak A., Janowski T.
Polish Journal of Veterinary Sciences
|
2013
|
tom 16
|
nr 1
The aim of this study was to compare the frequency of the occurrence of lip and/or palate cleft (CL/CP) in new-borns of two breeds, Pugs and Chihuahuas, and to measure the folic acid blood levels in bitches during gestations both with and without folic acid oral supplementation. Bitches of 13 Pugs and 17 Chihuahuas with CL/CP cases were used in the study. In trial 1, the animals of the experimental group (n=25) were given additional folic acid from the onset of heat till the 40th day of gestation. The females of the control group (n=12) were fed a traditional diet. From all the animals blood was collected at the onset of heat, 14 days later and on the 30th day of the gestation to estimate folic acid concentration. In trial 2, the prevalence of CP/CL cases in litters from pregnancies before and after supplementation was compared. The percentage of puppies with CL/CP after supplementation decreased in both Pugs and Chihuahua puppies (10.86% and 15.78% vs. 4.76% and 4.8% respectively). On Day 0, the concentrations of folic acid were at a low physiological level (around 8 ng/ml) in all the animals. In bitches of the experimental group the blood level of folic acid on day 14th and 30th of the treatment showed an increase in both breeds (13.65 ± 4.27 ng/ml in Pugs, 10.79 ± 2.84 ng/ml in Chihuahuas, and 14.94 ± 3.22 ng/ml in Pugs, 12.95 ± 3.58 in Chihuahuas, respectively) while in the control group, this level decreased with time of gestation both in Pugs and in Chihuahuas (around 6 ng/ml). Folic acid supplementation seems to be a simple, effective preventive method to reduce the risk of CL/CP, especially in the predisposed breeds.
5

Zywienie psow rosnacych

81%
Wisniewska M. E., Pomianowski A., Lesnik M., Domoslawska A.
Magazyn Weterynaryjny
|
2004
|
tom 13
|
nr 06
9-11
6

Struktura jakosciowa i ilosciowa grzybow przenoszonych przez Acarus siro

81%
Szlendak E., Wakulinski W., Boczek J., Domoslawska A.
Progress in Plant Protection
|
2008
|
tom 48
|
nr 1
146-149
7

Course of uterine involution and the level of progesterone in bitches with endometritis-pyometra complex treated with aglepristone

81%
Domoslawska A., Janowski T., Jurczak A.
Bulletin of the Veterinary Institute in Puławy
|
2010
|
tom 54
|
nr 1
19-23
The aim of the study was to estimate the uterus involution and progesterone level after antigestagene therapy in 12 bitches with a closed form of endometritis-pyometra complex (EPC). The bitches were of pure and mixed breeds, between 2 and 13 years of age. All the animals were treated with the same pattern: aglepristone was administrated at the dose of 0.33 mL/kg, s.c. on days 1, 2, 7, and 14. Additionally, amoxycyline was given at the dose of 1 mL/l0kg, s.c. every 48 h for 10 d. Complete elimination of puss masses and uterus involution were observed after 7-14 d of the treatment. Progesterone concentration was highly increased at the beginning of the treatment and was decreasing to low values during the first week of the therapy. Detectable uterus changes in the USG examination and physiological health status are not the only recovery criteria, but, most importantly, lack of recurrence of the EPC and the ability to deliver healthy progeny.
8

Blokery receptorow progesteronu [antygestageny] oraz ich zastosowanie w rozrodzie malych zwierzat

81%
Janowski T., Domoslawska A., Zdunczyk S.
Medycyna Weterynaryjna
|
2003
|
tom 59
|
nr 12
1064-1067
9

Implications of blood coagulation and fibrynolytic disorders in serve endometritis-pyometra complex in bitches

71%
Radwanska J., Domoslawska A., Pomianowski A., Zarczynska K., Jurczak A.
Bulletin of the Veterinary Institute in Puławy
|
2012
|
tom 56
|
nr 3
Twenty bitches with acute endometritis-pyometra complex (EPC) and 20 clinically healthy bitches were examined. The following coagulation parameters were determined in haemostatic evaluations: prothrombin time (PT), activated partial thromboplastin time (aPTT), thrombin time (TT), fibrinogen concentrations (FBG), D-dimer concentrations (D-D), antithrombin activity (AT), and blood platelet counts (PLT). Morphological and biochemical blood parameters were also analysed. Examinations of animals affected by EPC revealed blood coagulation and fibrinolytic disorders, and the noted results (PT 13.7 ±1.06 s, aPTT 23.4 ±1.04 s, TT 15.6 ±0.68 s, FBG 2.2 g/L, D-D 785.4 ±103.05 µg/L, AT 111.1 ±13.51%, PLT 169.30 ±126.31 10³/µL) point to a high risk of disseminated intravascular coagulation. The findings indicate that the coagulation parameters of bitches affected by EPC should be analysed before treatment as the noted disorder can significantly complicate therapy and ovariohysterectomy, and endanger the patients' life.
10

Effect of selenium and vitamin E supplementation on semen quality in dogs with lowered fertility

71%
Domoslawska A., Zdunczyk S., Nizanski W., Jurczak A., Janowski T.
Bulletin of the Veterinary Institute in Puławy
|
2015
|
tom 59
|
nr 1
Thirty clinicalh healthy dogs with poor semen quality were used in the study. Fifteen dogs were supplemented daily with selenium (0.6 mg/kg organic selenium from yeast) and vitamin E (5 mg/kg) per os for 60 d. The control group ( 15 dogs) was not supplemented. Semen was collected from all dogs by manual manipulation on days 0, 30, 60, and 90. The sperm concentration and motility parameters were evaluated with a Hamilton Thome sperm analy ser, version IVOS 12.3. For the assessment of sperm morphology, Diff-Quik stain was used. The percentage of live and dead spermatozoa was estimated on dried smears stained with eosin-nigrosin. The concentration of spermatozoa, most motility parameters determined (PMOT, VSL, VCL, ALH, BCF, RAPID, MEDIUM, SLOW, and STATIC), and the percentage of spermatozoa morphologically normal and live increased significantly (P < 0.05) after 60 d of supplementation. In the control group, there were no changes in motility parameters while the concentration and total sperm count decreased over the duration of the study. In conclusion, supplementation with selenium and vitamin E for 60 d can improve the quality of semen in dogs with lowered fertility.
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