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Experiments were carried out on male Balb/c mice, weighing 20 g. The Candida cells (Candida albicans L 45) were killed by heat-treatment and obsonized with mouse serum. Macrophages were obtained from the peritoneal cavity. Phagocytosis was executed by incubation 0,2 ml of suspension of macrophages with 0,2 ml of Candida suspension. Microscopic slides with cell smear were preparated. The phagocytic index and the percentage of phagocytizing macrophages were calculeted. It was found that infection with Trichinella spiralis or Trichinella pseudospiralis caused a significant reduction in the phagocytic capacity and the percentage of phagocytizing macrophages. This reduction depended on the intensity of invasion.
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Species composition of mosquitoes (Diptera, Culicinae) was investigated in 2000 year. The mosquitoes were caugh from april till october, twice a month, at 6 stations. Seven specics from genus Aedes were found: A. beclemishevi, A. ciprinus, A. cantans, A. flavescens, A. communis A. punctor, and A. vexans. A. cantans was most numerous (32,4). From genus Culex only one soecies was found (Culex pipiens). Furthermoce, Mansonia richardii and Culiseta annulata were caugh. The agresiveness toward men showed by mosquitoes was highest in august.
The development of Ascaris suum eggs in the culture containing prostaglandins (PGA, PGB, PGE and PGF) or inhibitors of their synthesis (indomethacin and acetylsalicylic acid) was studied. Exposure of eggs to indomethacin (0.2 and 0.5%) or acetylosalicylic acid (1 %) delayed the development. 0.5% acetylsalicylic acid didn't exert any effect. The development was also delayed by PGB, PGE, PGF and higher concentration of PGA. But lower concentration of PGA accelerated embryonic development.
Prostaglandins have been already pretty well rccognized as metabolic regulators in vertebebrata tissues mainly in mammals. Less reports concerned the occurrence of prostaglandins in invertebrates. In the present review we summarise literature data about the presence of prostaglandins and other eicosanoids in various groups of parasites and their possible role in hostparasite interaction. Prostaglandins have also been found in very primitive organisms as bacteria, varions plants and protozoa. We summarise that prostaglandins seem to be a very ancient group, going back to the roots of evolution. They are as universal in cell physiology as DNA in genetics. In host-parasiter eicosanoids also parasitic origin, play an important role as a modulators of hosts immune responsiveness.
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