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1

Effect of L-arginine and nitro-L-arginine methyl ester (L-NAME) on amphetamine and apomorphine induced stereotyped behavior and Dopac release in the striatum of rats

100%
Kasperska A., Brus R., Sokola A., Kostrzewa R. M.
Acta Neurobiologiae Experimentalis
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1999
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tom 59
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nr 3
2

Nitric oxide (NO) and central effects of the dopamine (DA) agonists on circulatory system in rats

100%
Nowak P., Brus P., Kasperska A., Szkilnik R.
Acta Neurobiologiae Experimentalis
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1997
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tom 57
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nr 5
3

Is there a relationship between inflammation and depression in athletes?

100%
Ostapiuk-Karolczuk J., Kasperska A., Botwina R.
Trends in Sport Sciences
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2015
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tom 22
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nr 3
Overtraining is a maladaptive state of athlete’s body related to the physical, behavioral and emotional condition, occurring when exercise training exceeds the recoverability. The cytokine hypothesis of overtraining promoted in recent years is seen as the prevailing theory explaining the understanding of the overtraining phenomenon. The high level of pro-inflammatory cytokines (IL-6, TNFα, IL-1β) involved in the inflammatory response may strongly influence not only the central nervous system but also the endocrine and immune systems. Moreover, there is a range of factors in athlete’s life that appear to increase the risk of depression development, such as psychological and emotional stress associated with sports competition. The aim of this review was to reveal the role of high level of proinflammatory cytokines observed in OTS with the possible occurrence of depression symptoms in athletes. Latest findings have shown an important role of the same pro-inflammatory cytokines in the development of depression. The study discusses a potential mechanism responsible for the development of depression in athletes, which may be helpful in the quick diagnosis of depression basis in athletes. Due to the low number of studies concerning depression and inflammation in athletes further research should be conducted.
4

Effect of L-Name and L-Arginine on irritability and aggressivity after central dopamine agonists apply in 5,7-DHT and 6-OHDA - neonatally lesioned rats

100%
Kasperska A., Oswiecimska J., Szkilnik R., Brus R.
Acta Neurobiologiae Experimentalis
|
1997
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tom 57
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nr 5
5

Effect of the aminoacid L-Arginine and its analog Nitro-L-Aginine methyl ester HCl (L-Name) on central dopamine (DA) receptor reactivity

88%
Brus R., Szkilnik R., Kasperska A., Oswiecimska J., Kostrzewa R. M.
Acta Neurobiologiae Experimentalis
|
1997
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tom 57
|
nr 5
6

Structural and functional characteristics of two novel members of pathogenesis-related multigene family of class from yellow lupine

88%
Handschuh L., Femiak I., Kasperska A., Figlerowicz M., Sikorski M. M.
Acta Biochimica Polonica
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2007
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tom 54
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nr 4
783-796
 PR-10 proteins (pathogensis-related), ubiquitous within the plant kingdom, are usually encoded by multigene families. To date we have identified 10 homologous pr-10 genes in a yellow lupine cDNA library. Here, the structure and expression of two newly identified yellow lupine pr-10 genes (LlYpr10-2b and LlYpr10-2f) are presented. Many potential regulatory sites were found in both gene promoters including common ones as well as those unique for each gene. However, promoter deletion analysis in transgenic tobacco plants revealed similar patterns of reporter gene (gus) expression. Shortened fragments of both gene promoters studied caused high GUS activity in leaves (along vascular bundles), stamen stigma, anthers and pollen grains. When conjugated with longer LlYpr-10.2 promoter fragments, GUS was additionally present in petal edges. Only a long fragment of the LlYpr10-2b gene promoter caused GUS expression in the stem. In yellow lupine the pr-10.2 genes are present in all studied organs, but their level of expression depends on the stage of development and is affected by wounding, oxidative stress and salicylic acid treatment. Silencing of the Llpr-10.2b gene in 4-week-old yellow lupine plants did not lead to any visible symptoms, which suggests that the function of the silenced gene is supplemented by its close homologues, still present in the studied plants.
7
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New insights into the signaling and function of cytokinins in higher plants

76%
Ciesielska A., Ruszkowski M., Kasperska A., Femiak I., Michalski Z., Sikorski M. M.
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
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2012
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tom 93
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nr 4
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