The moldavian dragonhead (Dracocephalum moldavica L., Lamiaceae) is an annual plant native in Central Asia and naturalized in Eastern and Central Europe where it is used in folk medicine as antiseptic and stimulating remedy. We carried out qualitative and quantitative phytochemical investigations on moldavian dragonhead herb and on its extracts (tincture and infusion). Plant samples were gathered in different stages of the ontogenesis from cultures in Hungary and Romania (Transylvania). In herb gathered during the reproductive stage of the ontogenesis we measured 0.83% (v/m) of essential oil, in which we identified by GC analysis five main components: geranyl acetate: 33.1%; geranial: 28.2%; neral: 19.8 %; geraniol: 8.2% and neryl acetate: 2.4%. In the essential oil distilled from tincture the geranyl acetate (58.2%) was the main component while in the volatile oil distilled from infusion, the major compound was geraniol (60.1%). A methanolic extract of the herb was investigated by HPLC. Following on-line analysis of spectra, five components were classified as flavonoids; rosmarinic acid was identified by addition of authentic standard. The amount of two phenol carboxylic acids (caffeic and rosmarinic acid) was measured by TLC-densitometry. High values of phenolic compounds were measured in samples gathered during the vegetative stage of the ontogenesis, such as: rosmarinic acid: 2.84 g%; caffeic acid: 50.3 mg%; total flavonoids: 0,58 g%; tannins: 12.9 g%.
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