Wyniki wyszukiwania

1

Components of metabolic syndrome and their impact on fetal growth in women with gestational diabetes mellitus

100%

Zawiejska A., Wender-Ozegowska E., Brazert J., Sodowski K.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

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nr 4

5-18

2

Epidemiology of peri-intraventricular haemorrhage in newborns at term

76%

Baumert M., Brozek G., Paprotny M., Walencka Z., Sodowska H., Cnota W., Sodowski K.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

|

nr 4

67-75

3

Microvessel density assessment in benign and malignant endometrial changes

76%

Czekierdowski A., Czekierdowska S., Czuba B., Cnota W., Sodowski K., Kotarski J., Zwirska-Korczala K.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

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nr 4

45-51

4

Leptin gene, leptin gene polymorphisms and body weight in pregnant women with diabetes mellitus type I

76%

Iciek R., Wender-Ozegowska E., Seremak-Mrozikiewicz A., Drews K., Sodowski K., Pietryga M., Brazert J.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

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nr 4

19-31

5

Microvessel density and CpG island methylation of THBS2 gene in malignant ovarian tumors

64%

Czekierdowski A., Czekierdowska S., Danilos J., Czuba B., Sodowski K., Sodowska H., Szymanski M., Kotarski J.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

|

nr 4

53-65

6

Osteopontyna potencjalny nowy, obok CA 125, marker w guzie jajnika

64%

Mrochem J., Sodowski K., Deja R., Walaszek-Gruszka A., Wojcieszek A., Kolosza Z., Maslyk B., Bartnik W.

Diagnostyka Laboratoryjna

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2007

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tom 43

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nr 3

7

Acylation stimulating protein is associated with pregnancy weight gain

64%

Sodowski K., Zwirska-Korczala K., Kuka D., Kukla M., Budziszewska P., Zebaty A., Wender-Ozegowska E., Baumert M., Wloch A.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

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nr 4

33-43

8

Doppler study of the peripheral flows in early gestation

52%

Wloch A., Sodowski K., Rozmus-Warcholinska W., Wloch S., Bodzek P., Czuba B., Borowski D., Cnota W., Kuka D., Szaflik K., Huhta J.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

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nr 4

77-85

9

Postprandial response of ghrelin and PYY and indices of low-grade chronic inflammation in lean young women with polycystic ovary syndrome

51%

Zwirska-Korczala K., Sodowski K., Konturek S. J., Kuka D., Kukla M., Brzozowski T., Cnota W., Wozniak-Grygiel E., Jaworek J., Buldak R., Rybus-Kalinowska B., Fryczkowski M.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

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nr 2

The aim of the study were to aswer the question 1.) Whether circulating pro-inflammatory markers of endothelial dysfunction and due to chronic low-grade inflammation of obesity, are altered in untreated lean, young relatively healthy polycystic ovary syndrome (PCOS) patients in comparison with healthy controls; 2.) Whether postprandial plasma concentration pattern of ghrelin and PYY can be predictable as risk factors for atherosclerosis and depend of obesity. Forty young women with PCOS were divided in two groups: 19 lean and 21 obese. The control group included 20 lean, healthy volunteers. Plasma total and active ghrelin, total PYY and PYY3-36, serum adiponectin and insulin were measured using RIA technique, serum sCD40L, visfatin, sP-, sE-selectins, resistin by EIA. Composition of test meal was: 527 kcal total and consisted of 24.1% fat, 54.4% carbohydrate and 21.5% protein. Total and active ghrelin and total PYY were significantly lower in obese PCOS women, whereas active ghrelin was also significantly lower in lean PCOS women compared to controls. Postprandial plasma total ghrelin levels decrease were blunted in lean and obese compared to controls (12.8 % and 18.2% vs 28.2 %). Postprandial plasma active ghrelin decreased in lean and obese PCOS groups (49.9 % and 44.1 %) and controls (63.8 %). PCOS subjects exhibited smaller rises in postprandial levels of total PYY. Postprandial plasma PYY3-36 levels increased in obese PCOS women (30.9 %) and controls (41%), whereas lean PCOS women exhibited blunted increase (11.5%). sCD40L levels increased, whereas adiponectin decreased in PCOS groups independently, whereas rise in visfatin, sE- and sP-selectin and the fall in adiponectin was associated with obesity. sP- and sE -selectins correlated positively with obesity. In summary, our study provides the first evidence that lean untreated young PCOS women contribute to the so called "pancreatic islet adaptation to insulin resistance" because of ghrelin and PYY profiles. We confirmed existing of low-grade chronic inflammation in early stage of visceral obesity in lean PCOS patients. The lost endogenous "islet adaptation to insulin resistance" may lead to endothelial dysfunction and promote acceleration of atherosclerosis.

Ograniczanie wyników

Components of metabolic syndrome and their impact on fetal growth in women with gestational diabetes mellitus

Epidemiology of peri-intraventricular haemorrhage in newborns at term

Microvessel density assessment in benign and malignant endometrial changes

Leptin gene, leptin gene polymorphisms and body weight in pregnant women with diabetes mellitus type I

Microvessel density and CpG island methylation of THBS2 gene in malignant ovarian tumors

Osteopontyna potencjalny nowy, obok CA 125, marker w guzie jajnika

Acylation stimulating protein is associated with pregnancy weight gain

Doppler study of the peripheral flows in early gestation

Postprandial response of ghrelin and PYY and indices of low-grade chronic inflammation in lean young women with polycystic ovary syndrome