Wyniki wyszukiwania

1

Woda jako atrybut warunkujacy ksztaltowanie obszarow wiejskich

100%

Cymerman R., Piekarska B.

Zeszyty Naukowe Akademii Rolniczej w Krakowie. Sesja Naukowa

|

1999

|

tom 68

113-118

2

Determinanty srodowiskowe reakcji immunologicznych w alergologii

100%

Piekarska B., Samolinski B. K.

Ochrona Środowiska i Zasobów Naturalnych

|

2007

|

nr 32

11-16

3

The effect of azo dyes on heat aggregation of IgG

81%

Piekarska B., Konieczny L., Rybarska J.

Acta Biochimica Polonica

|

1988

|

tom 35

|

nr 4

4

Ocena stężenia naczyniowo-śródbłonkowego czynnika wzrostu (VEGF) u chorych na raka gruczołu piersiowego

81%

Thielemann A., Kopczynski Z., Grodecka-Gazdecka S., Piekarska B.

Diagnostyka Laboratoryjna

|

2005

|

tom 41

|

nr 2

5

The formation of soluble heat IgG aggregates for immunological studies

81%

Rybarska J., Piekarska B., Konieczny L., Roterman I.

Archivum Immunologiae et Therapiae Experimentalis

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1988

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tom 36

|

nr 5

6

The effect of azo dyes on the formation of immune complexes

81%

Rybarska J., Konieczny L., Roterman I., Piekarska B.

Archivum Immunologiae et Therapiae Experimentalis

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1991

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tom 39

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nr 3

7

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

The melting of native domain structure in effector activation of IgG studied by using Congo Red as a specific probe

71%

Piekarska B., Roterman I., Rybarska J., Konieczny L., Kaszuba J.

Journal of Physiology and Pharmacology

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1994

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tom 45

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nr 1

8

Heat - induced structural changes in the Fab fragment of IgG recognized by molecular dynamics simulation - implications for signal transduction in antibodies

71%

Roterman I., Konieczny L., Stopa B., Rybarska J., Piekarska B.

Folia Biologica

|

1994

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tom 42

|

nr 3-4

9

Bis-azo dyes interference with efector activation of antibodies

71%

Kaszuba J., Konieczny L., Piekarska B., Roterman I., Rybarska J.

Journal of Physiology and Pharmacology

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1993

|

tom 44

|

nr 3

10

The detection of specific acute phase serum protein complexes and immune complexes by Congo Red binding

71%

Rybarska J., Konieczny L., Piekarska B., Stopa B., Roterman I.

Journal of Physiology and Pharmacology

|

1995

|

tom 46

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nr 2

11

Przeciwciała i nośniki leków w terapii celowanej - postęp i ograniczenia

61%

Konieczny L., Piekarska B., Roterman I., Rybarska J., Stopa B., Zemanek G.

Biotechnologia

|

2001

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nr 3

12

Consequences of smoke inhalation in the ‘Epidemiology of Allergic Diseases in Poland’ project (ECAP)

61%

Stankiewicz-Choroszucha B. L., Wawrzyniak Z. M., Lipiec A., Piekarska B., Kapalczynski W. J., Samolinski B. K.

Annals of Agricultural and Environmental Medicine

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2011

|

tom 18

|

nr 2

13

How to create drug delivery systems based on supramolecular compounds, proteins and carbon nanotubes?

61%

Jagusiak A., Piekarska B., Stopa B., Zemanek G., Chlopas K., Chmura O.

Acta Biochimica Polonica

|

2018

|

tom 65

|

nr S2

14

Bis azo dyes - studies on the mechanism of complex formation with IgG modulated by heating or antigen binding

61%

Roterman I., No K. T., Piekarska B., Kaszuba J., Pawlicki R., Rybarska J., Konieczny L.

Journal of Physiology and Pharmacology

|

1993

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tom 44

|

nr 3

15

Supramolecularity creates nonstandard protein ligands

61%

Piekarska B., Rybarska J., Stopa B., Zemanek G., Krol M., Roterman I., Konieczny L.

Acta Biochimica Polonica

|

1999

|

tom 46

|

nr 4

Congo red and a group of structurally related dyes long used to stain amyloid proteins are known to associate in water solutions. The self-association of some dyes belonging to this group appears particularly strong. In water solutions their molecules are arranged in ribbon-like micellar forms with liquid crystalline properties. These compounds have recently been found to form complexeswith some native proteins in a non-standard way. Gaps formed by the local distribution of β-sheets in proteins probably represent the receptor sites for these dye ligands. They may result from higher structural instability in unfolding conditions, but also may appear as long range cooperative fluctuations generated by ligand binding. Immunoglobulins G were chosen as model binding proteins to check the mechanism of binding of these dyes. The sites of structural changes generated by antigen binding in antibodies, believed to act as a signal propagated to distant parts of the molecule, were assumed to be suitable sites for the complexation of liquid-crystalline dyes. This assumption was confirmed by proving that antibodies engaged in immune complexation really do bind these dyes; as expected, this binding affects their function by significantly enhancing antigen binding and simultaneously inhibiting C1q attachment. Binding of these supramolecular dyes by some other native proteins including serpins and their natural complexes was also shown. The strict dependence of the ligation properties on strong self-assembling and the particular arrangement of dye molecules indicate that supramolecularity is the feature that creates non-standard protein ligands, with potential uses in medicine and experimental science.

16

In vivo accumulation of self-assembling dye Congo red in an area marked by specific immune complexes: possible relevance to chemotherapy

61%

Rybarska J., Piekarska B., Stopa B., Spolnik P., Zemanek G., Konieczny L., Roterman I.

Folia Histochemica et Cytobiologica

|

2004

|

tom 42

|

nr 2

17

Intramolecular signalling in immunoglobulins - new evidence emerging from the use of supramolecular protein ligands

61%

Piekarska B., Konieczny L., Rybarska J., Stopa B., Spolnik P., Roterman I., Krol M.

Journal of Physiology and Pharmacology

|

2004

|

tom 55

|

nr 3

The postulated intramolecular signaling in immunoglobulins generated by antigen binding has been controversial for years. The high heterogeneity of immune complexes as signaling systems and the requirement of the immobilized antigen form for efficient triggering of effector activity is likely the reason for the lack of clarity. Here we present new evidence supporting the notion of intramolecular signaling, based on the use of supramolecular dyes that bind to signal-derived specific sites in immunoglobulins.

18

Extent of protective or allergy-inducing effects in cats and dogs

52%

Krzych-Falta E., Furmanczyk K., Piekarska B., Raciborski F., Tomaszewska E., Walkiewicz A., Samel-Kowalik P., Borowicz J., Namyslowski A., Smolinski B. K.

Annals of Agricultural and Environmental Medicine

|

2018

|

tom 25

|

nr 2

19

Amyloids, Congo red and the apple-green effect

52%

Jagusiak A., Rybarska J., Konieczny L., Piekarska B., Stopa B., Chlopas K., Zemanem G., Roterman I.

Acta Biochimica Polonica

|

2019

|

tom 66

|

nr 1

20

Silver ions as EM marker of congo red ligation sites in amyloids and amyloid - like aggregates

52%

Rybarska J., Konieczny L., Jagusiak A., Chlopas K., Zemanek G., Piekarska B., Stopa B., Piwowar P., Woznicka O., Roterman I.

Acta Biochimica Polonica

|

2017

|

tom 64

|

nr 1

Ograniczanie wyników

Woda jako atrybut warunkujacy ksztaltowanie obszarow wiejskich

Determinanty srodowiskowe reakcji immunologicznych w alergologii

The effect of azo dyes on heat aggregation of IgG

Ocena stężenia naczyniowo-śródbłonkowego czynnika wzrostu (VEGF) u chorych na raka gruczołu piersiowego

The formation of soluble heat IgG aggregates for immunological studies

The effect of azo dyes on the formation of immune complexes

The melting of native domain structure in effector activation of IgG studied by using Congo Red as a specific probe

Heat - induced structural changes in the Fab fragment of IgG recognized by molecular dynamics simulation - implications for signal transduction in antibodies

Bis-azo dyes interference with efector activation of antibodies

The detection of specific acute phase serum protein complexes and immune complexes by Congo Red binding

Przeciwciała i nośniki leków w terapii celowanej - postęp i ograniczenia

Consequences of smoke inhalation in the ‘Epidemiology of Allergic Diseases in Poland’ project (ECAP)

How to create drug delivery systems based on supramolecular compounds, proteins and carbon nanotubes?

Bis azo dyes - studies on the mechanism of complex formation with IgG modulated by heating or antigen binding

Supramolecularity creates nonstandard protein ligands

In vivo accumulation of self-assembling dye Congo red in an area marked by specific immune complexes: possible relevance to chemotherapy

Intramolecular signalling in immunoglobulins - new evidence emerging from the use of supramolecular protein ligands

Extent of protective or allergy-inducing effects in cats and dogs

Amyloids, Congo red and the apple-green effect

Silver ions as EM marker of congo red ligation sites in amyloids and amyloid - like aggregates