The enzymes and electrolytes profiles in sera of Iranian stray dogs naturally infected with Neospora caninum

• Autorzy: Yakhchali M. , Bahrami M. , Asri-Rezaei S. , Bokaie S.
• Języki publikacji: EN

Abstrakty

EN

The protozoan Neospora caninum (Apicomplexa: Sarcocystidae), respectively infects canids and ruminants as the most definitive and intermediate hosts. A diagnosis of neosporosis is generally made on the basis of clinical signs together with the detection of high levels of antibodies in serum. The present study compares the serum electrolyte profile (Ca, K, Mg, Na, P) and serum enzyme level (ALP, AST, CPK) of non-infected dogs with those of stray dogs naturally infected with N. caninum. The indirect fluorescent antibody test (IFAT) revealed that 17 of the 137 analysed serum samples (12.41%) of the stray dogs were seropositive (Sp) to N. caninum. Serum levels of the electrolytes and the enzymes were evaluated in the 17 Sp and 28 seronegative (Sn, 20.44%) dogs using common enzyme kits, spectrophotometry and flame photometry techniques. The average serum level of ALP, AST, and CPK were found to be significantly higher in the Sp stray dogs. Measurements of the average serum levels of Ca, K, Mg, and P were higher in Sp than Sn stray dogs, with the average K level being significantly higher in seropositive stray dogs. It was concluded that evaluation of serum enzyme and electrolyte levels may be used to screen N. caninum infection in stray dogs.

• Wydawca: -
• Czasopismo: Annals of Parasitology
• Rocznik: 2017
• Tom: 63
• Numer: 1
• Opis fizyczny: p.63-68,ref.

Twórcy

autor

Yakhchali M.

• Parasitology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Nazlu Campus, Urmia 5756151818, Iran

autor

Bahrami M.

• Parasitology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Nazlu Campus, Urmia 5756151818, Iran

autor

Asri-Rezaei S.

• Clinical Pathology Division, Department of Clinical Sciences, Faculty of Veterinary Medicine, Urmia University, Nazlu Campus, Urmia 5756151818, Iran

autor

Bokaie S.

• Department of Food Hygiene, Faculty of Veterinary Medicine, University of Tehran, Tehran 1417466191, Iran

Bibliografia

• [1] Dubey J.P. 2003. Review of Neospora caninum and neosporosis in animal. The Korean Journal of Parasitology 41: 1-16. https://doi.org/10.3347/kjp.2003.41.1.1
• [2] Hemphill A. 1999. The host parasite relationship in neosporosis. In: Advances in Parasitology. (Eds. J.R. Backer, R. Muller, D. Rollinson). Vol. 43, Academic Press, London, UK: 47-104.
• [3] Hay W.H., Sheel L.G., Lindsay D.S., Dubey J.P. 1990. Diagnosis and treatment of Neospora caninum infection in a dog. Journal of American Veterinary Medicine Association 197: 87-89.
• [4] Barber J.S., Gasser R.B., Ellis J., Reichel M.P., McMillan D.A., Trees J. 1997. Prevalence of antibodies to Neospora caninum in different canid populations. Journal of Parasitology 83: 1056-1058. doi:10.2307/3284361
• [5] Barber J., Trees A.J. 1996. Clinical aspects of 27 cases of neosporosis in dogs. Veterinary Record 139: 439-443. doi:10.1136/vr.139.18.439
• [6] Sanchez G.F., Elizabeth-Morales S.E., Martínez M.J., Trigo J.F. 2003. Determination and correlation of anti-Neospora caninum antibodies in dogs and cattle from Mexico. Candian Journal of Veterinary Research 67: 142-145.
• [7] Hemphill A., Gottstein B. 2000. A European perspective on Neospora caninum. International Journal for Parasitology 30: 877-924.
• [8] Klein B.U., Müller E. 2001. Seroprävalenz von Antikörpern gegen Neospora caninum bei Hunden mit und ohne klinischen Neosporoseverdacht in Deutschland. Praktischer Tierärzt 82: 437-440.
• [9] Fernandes B.C.T.M., Gennari S.M., Souza S.L.P., Carvalho J.M., Oliveira W.G., Cury M.C. 2004. Prevalence of anti-Neospora caninum antibodies in dogs from urban, periurban and rural areas of the city of Uberlandia, Minas Gerais-Brazil. Veterinary Parasitology 123: 33-40.
• [10] Sawada M., Park C.H., Kondo H., Morita T., Shimada A., Yamane I., Umemura T. 1998. Serological survey of antibody to Neospora caninum in Japanese dogs. Journal Veterinary Medicine Science 60: 853-854.
• [11] Sadrebazzaz A., Haddadzadeh H., Esmailnia K., Habibi G., Vojgani M., Hashemifesharaki R. 2004. Serological prevalence of Neospora caninum in healthy and aborted dairy cattle in Mashhad, Iran. Veterinary Parasitology 124: 201-204.
• [12] Sadrebazzaz A., Haddadzadeh H., Shayan P. 2006. Seroprevalence of Neospora caninum and Toxoplasma gondii in camels (Camelus dromedarius) in Mashhad, Iran. Parasitology Research 98: 600-601. doi:10.1007/s00436-005-0118-3
• [13] Sadrebazzaz A., Habibi G., Haddadzadeh H., Ashrafi J. 2007. Evaluation of bovine abortion associated with Neospora caninum by different diagnostic techniques in Mashhad, Iran. Parasitology Research 100: 1257-1260. doi:10.1007/s00436-006-0417-3
• [14] Hajikolaei M. R., Hamidinejat H., Ghorbanpoor M., Goraninejad S. 2008. Serological study of Neospora caninum in cattle from Ahvaz area, Iran. International Journal of Veterinary Research 2: 63-66.
• [15] Haddadzadeh H.R., Sadrebazzaz A., Malmasi A., Talei Ardakani H., Khazraii Nia P., Sadreshirazi N. 2007. Seroprevalence of Neospora caninum infection in dogs from rural and urban environments in Tehran, Iran. Parasitology Research 101: 1563-1565. doi:10.1007/s00436-007-0678-5
• [16] Malmasi A., Hosseininejad M., Haddadzadeh H. 2007. Serologic study of anti-Neospora caninum antibodies in household dogs and dogs living in dairy and beef cattle farms in Tehran, Iran. Parasitology Research 100: 1143-1145. doi:10.1007/s00436-006-0385-7
• [17] Yakhchali M., Javadi S., Morshedi A. 2010. Prevalence of antibodies to Neospora caninum in stray dogs of Urmia, Iran. Parasitology Research 106: 1455-1458. doi:10.1007/s00436-010-1824-z
• [18] Coskun S.Z., Aydyn L., Bauer C. 2000. Seroprevalence of Neospora caninum infection in domestic dogs in Turkey. Veterinary Record 146: 649. doi:10.1136/vr.146.22.649
• [19] Mallah M.O., Dawood K.A., Alrodhan M.A. 2012. First isolation of Neospora caninum in dogs in Al-Muthana Province, Iraq. AL-Muthanna Journal of Pure Sciences 1: 217.
• [20] Williams D.J.L., Guy C.S., McGarry J.W., Guy F., Tasker L., Smith R.F., MacEachern K., Cripps P.J., Kelly D.F., Trees A.J. 2000. Neospora caninumassociated abortion in cattle: the time of experimentally-induced parasitaemia during gestation determines foetal survival. Parasitology 121: 347-358.
• [21] Dubey J.P., Schares G., Ortega-Mora L.M. 2007. Epidemiology and control of neosporosis and Neospora caninum. Clinical Microbiology Reviews 20: 323-367. doi:10.1128/CMR.00031-06
• [22] Dubey J.P., Lindsay D.S. 1996. A review of N. caninum and neosporosis. Veterinary Parasitology 67: 1-59.
• [23] Gharekhani J., Tavoosidana G.R., Akbarein H. 2014. Serological study of Neospora caninum infection in dogs and cattle from west of Iran. Comparative Clinical Pathology 23: 1203-1207. doi:10.1007/s00580-013-1763-z
• [24] Lorenzo V., Pumarola M., Siso S. 2002. Neosporosis with cerebellar involvement in an adult dog. Journal of Small Animal Practice 43:76-79. doi:10.1111/j.1748-5827.2002.tb00033.x
• [25] Dubey J.P., Dorough K.R., Jenkins M.C., Liddell S., Speer C.A., Kwok O.C.H., Shen S.K. 1998. Canine neosporosis: clinical signs, diagnosis, treatment and isolation of Neospora caninum in mice and cell culture. International Journal for Parasitology 28: 1293-1304.
• [26] Dubey J.P., Hattel A.L., Lindsay D.S., Topper M.J. 1988. Neonatal Neospora caninum infection in dogs: Isolation of the causative agent and experimental transmission. Journal of the American Veterinary Medical Association 193: 1259-1263.
• [27] Thrall M.A., Weiser G., Allison R., Campbell T.W. 2012. Veterinary hematology and clinical chemistry. Second ed., Wiley-Blackwell, John Wiley and Sons Inc., Ames, IA, USA.
• [28] Schalm O.W., Jain N.C., Carroll E.J. 1975. Veterinary hematology. Third ed., Lea and Febiger, Philadelphia, USA.
• [29] Dubey J.P., Knickman E., Greene C.E. 2005. Neonatal Neospora caninum infections in dogs. Acta Parasitologica 50: 176-179.
• [30] Trees A.J., Guy F., Tennant B.J., Balfour A.H., Dubey J.P. 1993. Prevalence of antibodies to Neospora caninum in a population of urban dogs in England. Veterinary Record 132: 125-126. doi:10.1136/vr.132.6.125
• [31] Cringol G., Calpuano F., Veneziano V. 1996. Prevalence of antibodies to Neospora caninum in dog sera. Parassitologia 38: 282.
• [32] Wouda W., Dijkstra T., Kramer A.M.H., Van Maanen C., Brinkhof J.M.A. 1999. Seroepidemiological evidence for a relationship between Neospora caninum infections in dogs and cattle. International Journal for Parasitology 29: 1677-1682.
• [33] Clooten J.K., Woods J.P., Smith-Maxie L.L. 2003. Myasthenia gravis and masticatory muscle myositis in a dog. Canadian Veterinary Journal 44: 480-483.
• [34] Aktas M., Auguste D., Lefebvre H.P. Toutain P.L., Braun J.P. 1993. Creatine Kinase in the dog: A review. Veterinary Research Communications 17: 353-369. doi:10.1007/BF01839386
• [35] Ettinger S.J., Feldman E.C. 2005. Textbook of veterinary internal medicine. Sixth ed., Elsevier Saunders, St. Louis, Missouri, USA.
• [36] Boyd S.P., Barr P.A., Brooks H.W., Orr J.P. 2005. Neosporosis in a young dog presenting with dermatitis and neuromuscular signs. Journal of Small Animal Practice 46: 85-88. doi:10.1111/j.1748-5827.2005.tb00298.x
• [37] Crookshanks J.L., Taylor S.M., Haines D.M., Shelton G.D. 2007. Treatment of canine pediatric Neospora caninum myositis following immunohistochemical identification of tachyzoites in muscle biopsies. Canadian Veterinary Journal 48: 506–508.

Identyfikatory

DOI

10.17420/ap6301.87