European bat lyssaviruses — an ecological enigma

• Autorzy: Vos A. , Kaipf I. , Denzinger A. , Fooks A. R. , Johnson N. , Muller T.
• Języki publikacji: EN

Abstrakty

EN

The first European case of bat rabies was reported in 1954. Since then, more than 800 cases have been confirmed from 13 countries. The causative agents are European Bat Lyssavirus Type-1 (EBLV-1) and Type-2 (EBLV-2). The natural host of EBLV-1 seems to be the serotine bat (Eptesicus serotinus) with more than 95% of all cases reported in this species. Although much fewer EBLV-2 cases have been identified, it seems that Myotis dasycneme and M. daubentonii are likely to be the principal hosts' species for this virus. The ecological mechanisms underlying the transmission of EBLV-1 and EBLV-2 are still poorly understood. In order to assess the public health risks associated with EBLVs and the implications for bat conservation, some issues need urgent clarification. In this review some of the most pressing topics will be addressed. Only collaboration between a range of disciplines that include virologists, epidemiologists and bat conservationists will be able to elucidate some of these unanswered questions.

Słowa kluczowe

EN

European bat; bat; lyssavirus; Chiroptera; rabies; ecology; Eptesicus serotinus; Myotis dasycneme; Myotis daubentonii; European bat lyssavirus type-1; European bat lyssavirus type-2; virology

• Wydawca: -
• Czasopismo: Acta Chiropterologica
• Rocznik: 2007
• Tom: 09
• Numer: 1
• Opis fizyczny: p.283-296,fig.,ref.

Twórcy

autor

Vos A.

• Impfstoffwerk Dessau Tornau GmbH, Streetzerweg 15a, 06862 Rodleben, Germany

autor

Kaipf I.

autor

Denzinger A.

autor

Fooks A. R.

autor

Johnson N.

autor

Muller T.

Bibliografia

• 1. D. B. Adams and G. M. Baer . 1966. Cesariary section and artificial feeding device for suckling bats. Journal of Mammalogy 47:524–525. Google Scholar
• 2. M. F. Almeida, L. F A. Martorelli, C. C. Aires, P. C. Sallum, E. L. Durigon, and E. Massad . 2005. Experimental rabies infection in heamatophagous bats Desmodus rotundus. Epidemiology and Infection 133:523–527. Google Scholar
• 3. B. Amengual, J. E. Whitby, A. King, J. S. Cobo, and H. Bourhy . 1997. Evolution of European bat lyssaviruses. Journal of General Virology 78:2319–2328. Google Scholar
• 4. Anonymous 1986. Bat rabies in the Union of Soviet Socialist Republics. Rabies Bulletin Europe 10:12–14. Google Scholar
• 5. Anonymous 1989. Observations on the course of a bat rabies case in the Federal Republic in Germany. Rabies Bulletin Europe 13:11. Google Scholar
• 6. A. Aquilar-Setien, B. Brochier, N. Tordo, O. De Paz, P. Desmettre, D. Peharpre, and P. P. Pastoret . 1998. Experimental rabies infection and oral vaccination in vampire bats (Desmodus rotundus). Vaccine 16:1122–1126. Google Scholar
• 7. H. Badrane and N. Tordo . 2001. Host switching in Lyssavirus history from the Chiroptera to the Carnivora orders. Journal of Virology 75:8096–8104. Google Scholar
• 8. J. Barrat, M. Artois, and H. Bourhy . 1989. Two bats diagnosed rabid in France. Rabies Bulletin Europe 13:10–11. Google Scholar
• 9. A. D. Botvinkin, E. M. Poleschuk, I. V. Kuzmin, T. I. Borisova, S. V. Gazaryan, P. Yager, and C. E. Rupprecht . 2003. Novel lyssavirus isolated from bats in Russia. Emerging Infectious Diseases 9:1623–1625. Google Scholar
• 10. H. Bourhy, B. Kissi, M. Lafon, D. Sacramento, and N. Tordo . 1992. Antigenic and molecular characterization of bat rabies virus in Europe. Journal of Clinical Microbiology 30:2419–2426. Google Scholar
• 11. D. A. Brass 1994. Rabies in bats — natural history and public health implications Livia Press. Ridgefield. 352. pp. Google Scholar
• 12. S. M. Brookes, J. N. Aegerter, G. C. Smith, D. M. Healy, T. A. Jolliffe, S. M. Swift, I. J. Mackei, J. S. Pritchard, P. A. Racey, N. P. Moore, and A. R. Fooks . 2005a. European bat lyssaviruses in Scottish bats. Emerging Infectious Diseases 11:572–578. Google Scholar
• 13. S. M. Brookes, G. Parsons, N. Johnson, L. M. Mcelhinney, and A. R. Fooks . 2005b. Rabies human diploid cell vaccine elicits cross-neutralising and cross-protecting immune responses against European and Australian bat lyssaviruses. Vaccine 23:4101–4109. Google Scholar
• 14. S. M. Brookes, R. Klopfleisch, T. Muller, D. M. Healey, J. Tiefke, E. Lange, J. Kliemt, N. Johnson, C. Finnegan, L. Johnson, V. Kaden, A. Vos, and A. R. Fooks . 2006. Differences between EBLV-1 and EBLV-2 pathogenesis: sheep as a model of disease recovery. P. 62. in. Abstracts of the XVII International Conference Rabies in the Americas October 15–20. Brasilia. Brazil. Google Scholar
• 15. A. Brosset 1990. Les migrations de la pipistrelle de Nathusius, Pipistrellus nathusii, en France. Ses incidences possibles sur la propagation de la rage. Mammalia 54:207–212. Google Scholar
• 16. Z. Bruijn 2003. Behavioural observations in some rabid bats. Rabies Bulletin Europe 27:7–8. Google Scholar
• 17. C. H. Calisher, J. E. Childs, H. E. Field, K. V. Holmes, and T. Schountz . 2006. Bats: important reservoir hosts of emerging viruses. Clinical Microbiology Reviews 19:531–545. Google Scholar
• 18. A. K. Chakravarty and S. K. Sarkar . 1994. Immunofluorescence analysis of immunoglobulin bearing lymphocytes in the Indian fruit bat: Pteropus giganteus. Lymphology 27:97–104. Google Scholar
• 19. D. G. Constantine 1962. Rabies transmission by nonbite route. Public Health Reports 77:287–289. Google Scholar
• 20. D. G. Constantine, G. C. Solomon, and D. F. Woodall . 1968. Transmission experiments with bat rabies isolates: responses of certain carnivores and rodents to rabies viruses from four species of bats. American Journal of Veterinary Research 29:181–190. Google Scholar
• 21. P. L. Davis, E. C. Holmes, F. Larrous, W. H. Van der Poel, K. Tjornehoj, W. J. Alonso, and H. Bourhy . 2005. Phylogeography, population dynamics, and molecular evolution of European bat lyssaviruses. Journal of Virology 79:10487–10497. Google Scholar
• 22. P. L. Davis, H. Bourhy, and E. C. Holmes . 2006. The evolutionary history and dynamics of bat rabies. Infection, Genetics and Evolution 6:464–473. Google Scholar
• 23. M. De Boo 2002. Bomen, beesten en buitens, Staatsbosbeheer in Gelderland Staatsbosbeheer. Arnhem. 280. pp. Google Scholar
• 24. J. E. Echevarria, A. Avellon, J. Juste, M. Vera, and C. Ibañez . 2001. Screening of active lyssa-virus infection in wild bat populations by viral RNA on oropharyngeal swabs. Journal of Clinical Microbiology 39:3678–3683. Google Scholar
• 25. C. O. Everard and J. D. Everard . 1988. Mongoose rabies. Reviews of Infectious Diseases 10:S610–S614. Google Scholar
• 26. A. R. Fooks, S. M. Brookes, N. Johnson, L. M. Mcelhinney, and A. M. Hutson . 2003. European bat lyssavirus: an emerging zoonoses. Epidemiology and Infection 131:1029–1039. Google Scholar
• 27. T. Gaede 1992. Bat rabies in Denmark 1985–1990. Pp 76–78. in Wildlife rabies control K. Bögel, F. X. Meslin, and M. Kaplan , editors. eds. Wells Medical Ltd. Kent. 222. pp. Google Scholar
• 28. R. V. Gibbons 2002. Cryptogenic rabies, bats, and the question of aerosol transmission. Annals of Emergency Medicine 39:528–536. Google Scholar
• 29. P. C. Grauballe, H. J. Baagøe, M. Fekadu, J. M. Westergaard, and H. Zoffmann . 1987. Bat rabies in Denmark. Lancet 1:379–380. Google Scholar
• 30. S. L. Harris, S. M. Brookes, G. Jones, A. M. Hutson, P. A. Racey, J. Aegerter, G. C. Smith, L. M. Mcelhinney, and A. R. Fooks . 2006a. European bat lyssaviruses: distribution, prevalence and implications for conservation. Biological Conservation 131:193–210. Google Scholar
• 31. S. L. Harris, S. M. Brookes, G. Jones, A. M. Hutson, and A. R. Fooks . 2006b. Passive surveillance (1987 to 2004) of United Kingdom bats for European bat lyssaviruses. Veterinary Record 159:439–446. Google Scholar
• 32. G. J. Hughes, L. A. Orciari, and C. E. Rupprecht . 2005. Evolutionary timescale of rabies virus adaptation to North America bats inferred from the substitution rate of the nucleoprotein gene. Journal of General Virology 86:1467–1474. Google Scholar
• 33. G. J. Hughes, I. V. Kuzmin, A. Schmitz, J. Blanton, J. Manangan, S. Murphy, and C. E. Rupprecht . 2006. Experimental infection of big brown bats (Eptesicus fuscus) with Eurasian bat lyssaviruses Aravan, Khujand, and Irkut virus. Archives of Virology 151:2021–2035. Google Scholar
• 34. R. Hutterer, T. Ivanova, C. Meyer-Cords, and L. Rodriquez . 2005. Bat migration in Europe — a review of banding data and literature Bundesamt fuer Naturschutz. Bonn - Bad Godesberg. 162. pp. Google Scholar
• 35. N. Johnson, D. Selden, G. Parsons, D. Healy, S. M. Brookes, L. M. Mcelhinney, A. M. Hutson, and A. R. Fooks . 2003. Isolation of a European bat lyssavirus type 2 from a Daubenton's bat in the United Kingdom. Veterinary Record 152:383–387. Google Scholar
• 36. N. Johnson, P. R. Wakeley, M. S. Brookes, and A. R. Fooks . 2006. European bat lyssavirus Type 2 RNA in Myotis daubentonii. Emerging Infectious Diseases 12:1142–1144. Google Scholar
• 37. A. Kappeler 1989. Bat rabies surveillance in Europe. Rabies Bulletin Europe 13:12–13. Google Scholar
• 38. A. Kappeler 1992. First case of rabies in a bat in Switzerland. Rabies Bulletin Europe 16:11. Google Scholar
• 39. K. Kapteyn 1995. Vleermuizen in het landschap; over hun ecologie, gedrag en verspreiding Schuyt and Co. Haarlem. 224. pp. Google Scholar
• 40. K. Kapteyn 1997. Laatvlieger Eptesicus serotinus (Schreber, 1774). Pp 191–201. in Atlas van de Nederlandse vleermuizen: onderzoek naar verspreiding en ecologie H. Limpens, K. Mostert, and W. Bongers , editors. eds. KNNV Uitgeverij. Utrecht. 260. pp. Google Scholar
• 41. A. A. King, J. Haagsma, and A. Kappeler . 2004. Lyssavirus infections in European bats. Pp 221–242. in Historical perspective of rabies in Europe and the Mediterranean Basin A. A. King, A. R. Fooks, M. Aubert, and A. I. Wandeler , editors. eds. Office Internationale des Epizootics. Paris. 361. pp. Google Scholar
• 42. T. Kuiken, E. C. Holmes, J. Mccauley, G. F. Rimmelzwaan, C. S. Williams, and B. T. Grenfell . 2006. Host species barriers to influenza virus infections. Science 312:394–397. Google Scholar
• 43. T. H. Kunz and M. B. Fenton . (eds.). 2003. Bat ecology University of Chicago Press. Chicago. 798. pp. Google Scholar
• 44. I. V. Kuzmin and A. D. Botvinkin . 1996. The behaviour of bats Pipistrellus pipistrellus after experimental inoculation with rabies and rabies-like viruses and some aspects of pathogenesis. Myotis 34:93–99. Google Scholar
• 45. I. V. Kuzmin, L. A. Orciari, Y. T. Arai, J. S. Smith, C. A. Hanlon, Y. Kameoka, and C. E. Rupprecht . 2003. Bat lyssaviruses (Aravan and Khujand) from Central Asia: phylogenetic relationships according to N, P and G gene sequences. Virus Research 97:65–79. Google Scholar
• 46. I. V. Kuzmin, A. D. Botvinkin, E. M. Poleschuk, L. A. Orciai, and C. E. Rupprecht . 2006. Bat rabies surveillance in the former Soviet Union. Developments in Biologicals 125:273–282. Google Scholar
• 47. D. W. Macdonald 1980. Rabies and wildlife: a biologist's perspective Oxford University Press. Oxford. 151. pp. Google Scholar
• 48. D. A. Marston, L. M. Mcelhiney, N. Johnson, T. Müller, K. K. Conzelmann, N. Tordo, and A. R. Fooks . 2007. Comparative analysis of the full genome sequence for European bat lyssavirus type-1 and type-2 with other lyssaviruses and evidence for a conserved transcription termination and polyadenylation motif in the G-L 3′-non-translated region. Journal of General Virology 88:1302–1314. Google Scholar
• 49. K. A. Mccoll, N. Tordo, and A. A. Aguilar-Setien . 2000. Bat lyssavirus infections. Revue Scientifique et Technique 19:177–196. Google Scholar
• 50. S. Mollgaard 1985. Bat-rabies in Denmark. Rabies Bulletin Europe 9:8. Google Scholar
• 51. T. H. Müller, J. H. Cox, W. Müller, and H. Schlüter . 2001. Bat rabies in Germany with emphasis on molecular comparison of EBL isolates. P. 31. in. Abstracts of the 12th International Meeting on Advances in Rabies Research and Control in the Americas November 12–16, 2001. Peterborough, Ontario. Canada. Google Scholar
• 52. T. Müller, N. Johnson, C. M. Freuling, A. R. Fooks, T. Selhorst, and A. Vos . 2007. Epidemiology of bat rabies in Germany. Archives of Virology 152:273–288. Google Scholar
• 53. W. W. Müller 1992. Recent bat rabies epizootic in Europe — a review. Pp 65–69. in Wildlife rabies control K. Bögel, F. X. Meslin, and M. Kaplan , editors. eds. Wells Medical Ltd. Kent. 222. pp. Google Scholar
• 54. B. Paul and A. K. Chakravarty . 1986. In vitro analysis of delayed immune response in a bat, Pteropus giganteus: process of con-A mediated activation. Developmental Comparative Immunology 10:55–67. Google Scholar
• 55. J. L. Perez-Jorda, C. Ibañez, M. Munoz-Cervera, and A. Tellez . 1995. Lyssavirus in Eptesicus serotinus (Chiroptera, Vespertilionidae). Journal of Wildlife Diseases 31:372–377. Google Scholar
• 56. E. Petit and F. Mayer . 2000. A population genetic analysis of migration: the case of the noctule bat (Nyctalus noctula). Molecular Ecology 9:683–690. Google Scholar
• 57. E. Picard-Meyer, J. Barrat, E. Tissot, A. Verdot, C. Patron, M. J. Barrat, and F. Cliquet . 2006. Bat rabies surveillance in France, from 1989 through May 2005. Development in Biologicals 125:283–288. Google Scholar
• 58. R. C. Rosatte and J. R. Gunson . 1984. Presence of neutralizing antibodies to rabies virus in striped skunks from areas free of skunk rabies in Alberta. Journal of Wildlife Diseases 20:171–176. Google Scholar
• 59. R. Schindler and H. K. Denning . 1958. Unter-suchungen über die Bedeutung der Fledermäuse für den gegenwärtigen Tollwut-Seuchenzug in Deutschland. Monatsschrift für Tierheilkunde 10:169–177. Google Scholar
• 60. L. G. Schneider and J. H. Cox . 1994. Bat lyssa-viruses in Europe. Current Topics in Microbiology and Immunology 187:207–218. Google Scholar
• 61. M. Seidler, H-J. Brehmer, B. Pott B, J. H. Cox, and H. Zinke . 1987. Tollwut bei Fledermäusen in Niedersachsen. Berliner und Münchener Tierärztliche Wochenschrift 100:199–203. Google Scholar
• 62. J. Serra-Cobo, B. Amengual, C. Abellán, and H. Bourhy . 2002. European bat lyssavirus infection in Spanish bat populations. Emerging Infectious Diseases 8:413–420. Google Scholar
• 63. V. Shankar, R. A. Bowen, A. D. Davis, C. E. Rupprecht, and T. J. O'Shea . 2004. Rabies in a colony of big brown bats (Eptesicus fuscus). Journal of Wildlife Diseases 40:403–413. Google Scholar
• 64. V. Shankar, L. A. Orciari, C. D. Mattos, I. V. Kuzmin, W. J. Pape, T. J. O'Shea, and C. E. Rupprecht . 2005. Genetic divergence of rabies viruses from bat species of Colorado, USA. Vector-Borne Zoonotic Diseases 5:330–341. Google Scholar
• 65. R. A. Simms, R. Allen, and S. E. Sulkin . 1963. Studies of the pathogenesis of rabies in insectivorous bats III influence of the gravid state. Journal of Infectious Diseases 112:17–27. Google Scholar
• 66. G. C. Smith, S. M. Brookes, S. L. Harris, J. N. Aegerter, G. Jones, and A. R. Fooks . 2006. EBLV-2 prevalence in the United Kingdom as determined by surveillance testing. Developments in Biologicals 125:265–171. Google Scholar
• 67. J. S. Smith, L. A. Orciari, and P. A. Yager . 1995. Molecular epidemiology of rabies in the United States. Virology 6:387–400. Google Scholar
• 68. R. S. Steece and C. H. Calisher . 1989. Evidence for prenatal transfer of rabies virus in the Mexican free-tailed bat (Tadarida brasiliensis mexicana). Journal of Wildlife Diseases 25:329–334. Google Scholar
• 69. W. H M. Van der Poel, R. Van der Heide, G. Van Amerongen, L. J M. Van Keulen, G. J. Wellenberg, H. Bourhy, W. Schaftenaar, J. Groen, and A. D M. E. Osterhaus . 2000. Characterisation of a recently isolated lyssavirus in frugivorous zoo bats. Archives of Virology 145:1919–1931. Google Scholar
• 70. W. H M. Van der Poel, R. Van der Heide, E. R A. M. Verstaten, K. Takumi, P. H C. Lina, and J. A. Kramps . 2005. European bat lyssaviruses, the Netherlands. Emerging Infectious Diseases 11:1854–1859. Google Scholar
• 71. W. H M. Van der Poel, P. H C. Lina, and J. A. Kramps . 2006. Public health awareness of emerging zoonotic viruses of bats: a European perspective. Vector-Borne and Zoonotic Diseases 6:315–324. Google Scholar
• 72. S. Vazquez, C. Ibañez, J. Juste, and J. E. Echevarria . 2006. EBLV1 circulation in natural bat colonies of Eptesicus serotinus: a six year survey. Developments in Biologicals 125:257–261. Google Scholar
• 73. A. Vos, T. Müller, L. Neubert, A. Zurbriggen, C. Botteron, D. Pöhle, H. Schoon, L. Haas, and A. Jackson . 2004a. Rabies in red foxes (Vulpes vulpes) experimentally infected with European bat lyssavirus Type 1 (EBLV-1). Journal of Veterinary Medicine 51B:327–332. Google Scholar
• 74. A. Vos, T. Müller, J. Cox, L. Neubert, and A. R. Fooks . 2004b. Susceptibility of ferrets (Mustela putorius furo) to experimentally induced rabies with European bat lyssaviruses (EBLV). Journal of Veterinary Medicine 51B:55–60. Google Scholar
• 75. A. Vos, N. Johnson, T. Müller, L. Neubert, R. Franka, I. Kaipf, K. Mansfeld, C. Freuling, A. Denzinger, C. E. Rupprecht, and A. R. Fooks . 2006. Experimental infection of Eptesicus fuscus with European bat lyssavirus Type 1. P. 61. in. Abstracts of the XVII International Conference Rabies in the Americas October 15–20. Brasilia. Brazil. Google Scholar
• 76. Vereniging voor Zoogdierkunde en Zoogdierbescherming 2006. Jaarboek 2005 Vereniging voor Zoogdierkunde en Zoogdierbescherming. Arnhem. 66. pp. Google Scholar
• 77. A. I. Wandeler, S. A. Nadin-Davis, R. R. Tinline, and C. E. Rupprecht . 1994. Rabies epidemiology: some ecological and evolutionary perspectives. Pp 297–324. in Lyssaviruses B. Dietzschold, H. Koprowski, and C. E. Rupprecht , editors. eds. Springer Verlag. Berlin. 350. pp. Google Scholar
• 78. J. E. Whitby, P. R. Heaton, E. M. Black, M. Wooldridge, L. M. Mcelhinney, and P. Johnstone . 2000. First isolation of a rabies-related virus from a Daubenton's bat in the United Kingdom. Veterinary Record 147:385–388. Google Scholar