Ascorbic acid and tocopherol levels in the organs and serum of guinea pigs with experimentally induced atherosclerosis

• Autorzy: Ziemianski S. , Wartanowicz M. , Potrzebicka K. , Panczenko-Kresowska B.
• Języki publikacji: EN

Abstrakty

EN

Ziemlański, Ś., Wartanowicz, M., Potrzebnicka, K., and Panczenko-Kresowska, B.: Ascorbic acid and tocopherol levels in the organs and serum of guinea pigs with experimentally induced atherosclerosis. Acta physiol, pol., 1989, 40(5-6): 552-557. A 7-month experiment was carried out on ginea pigs to elucidate the effect of hight-cholesterol diet containing various fats on the levels of ascorbic acid and to tocopherol in the organism. In the guinea pigs with experimentally induced atherosclerosis the retention of ascorbic acid and tocopherol was found to be greater than that in the control animals.

• Wydawca: -
• Czasopismo: Acta Physiologica Polonica
• Rocznik: 1989
• Tom: 40
• Numer: 5-6
• Opis fizyczny: p.552-557,ref.

Twórcy

autor

Ziemianski S.

• Department of Physiology and Biochemistry, Human Nutrition National Institute of Food and Nutrition, Warsaw, Poland

autor

Wartanowicz M.

• Department of Physiology and Biochemistry, Human Nutrition National Institute of Food and Nutrition, Warsaw, Poland

autor

Potrzebicka K.

• Department of Physiology and Biochemistry, Human Nutrition National Institute of Food and Nutrition, Warsaw, Poland

autor

Panczenko-Kresowska B.

• Department of Physiology and Biochemistry, Human Nutrition National Institute of Food and Nutrition, Warsaw, Poland

Bibliografia

• 1. Cerutti, P. A. (1985) Prooxidant state and tumor promotion. Science 227. 375-381.
• 2. Ciechanowski, K. (1988) Nowe spojrzenie na rolę wolnych rodników w ostrym niedokrwieniu mięśnia sercowego. Kardiol. Pol. 31. 1-6.
• 3. Chow, С. K. (1979) Nutritional influence on cellular antioxidant defense system. Am. J. Clin. Nutr. 32. 1066-1081.
• 4. Dworski, R., Domagała, В., Hartwich, J. et al. (1986) Wpływ witaminy E na zachowanie sięnadtlenków lipidów w osoczu i agregację płytek krwi u chorych z hiperlipoproteinemią. Pol. Arch. Med. Wew. 75. 293-240.
• 5. Ginter, E., Bobek, P. (1981) The influence of vitamin C on lipid metabolism in: Vitamin C (Ascorbic acid), eds. J. N. Counsell, D. H. Homing, pp. 299-347, Applied Science Publishers, London and New Jersey.
• 6. Gey, K. F. (1986) On the antioxidant hypothesis with regard to atherosclerosis. Bibl. Nutr. Dieta 37. 53-91.
• 7. Gey, K. F., Brubacher, G. B., Stachelin, H. B. (1987) Plasma levels of antioxidant vitamins in relation to ischemic heart disease and cancer. Am. J. Clin. Nutr. 45. 1368-1377.
• 8. Hanck, A., Weiser, H. (1979) The influence of vitamin C on lipid metabolism in man and animals. Int. J. Vit. Nutr. Res. 19. 83-93.
• 9. Hashim, S. A., Schuttringer, G. R. (1966) Rapid determination of tocopherol in macro and microquantities of plasma. Am. J. Clin. Nutr. 19. 137-144.
• 10. Hermus, R. J. (1975) Experimental atherosclerosis in rabbits on diets with milk fat and different proteins. Ed. Centre for Aricultural Publishing and Documentation, pp. 91.
• 11. Herbaczyńska-Cedro, K., Gordon-Majchrzak, W. (1987) Increased peroxidation of myocardial lipids in nonischemic portion of the heart with coronary occlusions. Acta Physiol. Pol. supp. 30. 38. 97 (Abstract).
• 12. Kitaba, M., Smimizu, J., Miyake, K., et al. (1978) Studies on vitamin E in lipid metabolism. In Tocopherol, Oxygen and Biomembranes, eds. de Duve, Hayishi-Elsevier North-Holland, Biomedical Press, Amsterdam, pp. 263.
• 13. Kono, K., Hyakawa, M., Asai, K., Kuzuya, E. (1987) Risk factors of atherogenecity in inherently scorbutic rats. J. Nutr. Sci. Vitam. 33. 1-10.
• 14. Lowry, О. H., Lopez, J. A., Bessey, O. A. (1945) The determination of ascorbic acid in small amounts of blood serum. J. Biol. Chem. 160. 609-612.
• 15. Maugh, T. H. (1984) Tracking exposure to toxic substances. Science 1984, 226. 1183-1184.
• 16. Sulkin, N. M., Sulkin, D. F. (1960) Intestinal lesions in arteries of vitamin E deficient rats. Proc. Soc. Exp. Biol. Med. 103. 111.
• 17. Taylor, S. L., Lambden, M. P., Tapel, Al. L. (1976) Sensitive fluorimetric method for tissue tocopherol analysis. Lipids 11. 530-538.
• 18. Turley, S. D., West, С. E., Horton, B. J. (1976) The role of ascorbic acid in the pathogenesis of atherosclerosis. Atherosc. 24. 1-5.
• 19. Wartanowicz, M., Panczenko-Kresowska, B., Ziemlański, S. et al. (1984) The effect of α-tocopherol and ascorbic acid on the serum lipid peroxide level in elderly people. Ann. Nutr. Metab. 28. 186-191.
• 20. Weitberg, A. B., Witzman, S. A., Destrempes, M. et al. (1983) Stimulated human phagocytes produce cytogenic changes in cultured mammalian cells. New. Engl. J. Med. 308. 26.
• 21.Wilson, R. B., Middleton, C. C., Sun, G. Y. (1978) Vitamin E, antioxidant and lipid peroxidation in experimental atherosclerosis of rabbits. J. Nutr. 108. 1858-1867.
• 22. Ziemlański, S, Panczenko-Kresowska, B., Wartanowicz, M. et al.( 1986) The effect of two-year supplementation with ascorbic acid and alpha-tocopherol on lipid, haematological and vitamin state in elderly women. Żywienie Człowieka i Metabolizm 13.7-13.
• 23. Ziemlański, S., Panczenko-Kresowska, B., Wielgus-Serafińska, E. et al. (1987) Cod-liver oil effect on the development of experimental atherosclerosis. Nutr. Internat. 3. 104-109.
• 24. Ziemlański, S., Wartanowicz, M., Potrzebnicka, K. et al. The influence of polyunsaturated fatty acids on serum and tissue ascorbic acid and tocopherol content in laboratory animals (in Polish). Polish Journal of Human Natrition and Metabolism (in print).