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2018 | 77 | 4 |

Tytuł artykułu

Histological and immunohistochemical characterisation of uterine adenocarcinoma in an Asian elephant (Elephas Maximus)

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
A 56-year-old nulliparous female Asian elephant (Elephas maximus) living at the zoological garden of Naples (Italy), with a clinical history of recurrent colic, was found in agonal state and humane euthanasia was elected. At necropsy the uterine body was moderately increased in size and the lumen was reduced due to a poorly demarcated and infiltrative neoplasm. Furthermore, multiple, whitish, firm nodules were present in both lungs. Histological examination of the uterine mass revealed epithelial cells arranged in tubular or solid pattern infiltrating the endometrium and the muscular layer. Immunohistochemical examination showed immunoreactivity of neoplastic cells to oestrogen receptors antibody. Pulmonary lesions were histologically and immunohistochemically superimposable to the epithelial uterine neoplasm. A definitive diagnosis of uterine adenocarcinoma with pulmonary metastases was made. (Folia Morphol 2018; 77, 4: 771–774)

Słowa kluczowe

Wydawca

-

Czasopismo

Rocznik

Tom

77

Numer

4

Opis fizyczny

p.771–774,fig.,ref.

Twórcy

  • Zoological Garden Lo Zoo di Napoli, Naples, Italy
autor
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via F. Delpino 1, 80137 Naples, Italy
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via F. Delpino 1, 80137 Naples, Italy
autor
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via F. Delpino 1, 80137 Naples, Italy
autor
  • Zoological Garden Lo Zoo di Napoli, Naples, Italy
autor
  • Zoological Garden Lo Zoo di Napoli, Naples, Italy
autor
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via F. Delpino 1, 80137 Naples, Italy
autor
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via F. Delpino 1, 80137 Naples, Italy

Bibliografia

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  • 2. Benshushan A. Endometrial adenocarcinoma in young patients: evaluation and fertility-preserving treatment. Eur J Obstet Gynecol Reprod Biol. 2004; 117(2): 132–137, doi: 10.1016/j.ejogrb.2004.05.015, indexed in Pubmed: 15541846.
  • 3. Elsinghorst TA, Timmermans HJ, Hendriks HG. Comparative pathology of endometrial carcinoma. Vet Q. 1984; 6(4): 200–208, doi: 10.1080/01652176.1984.9693937, indexed in Pubmed: 6388139.
  • 4. Kennedy PC, Cullen JM, Edwards JF. World health organization international histologic classification of tumors of domestic animals. Histological classification of tumors of the skin of domestic animals, 2nd series, vol. III. Armed Forces Institute of Pathology, Washington. 1998.
  • 5. Kidsadagon P, Hiroo M, Jiraporn S, et al. Histopathological and immunohistochemical characterization of spontaneous uterine leiomyomas in two captive asian elephants. Thai J Vet Med. 2015; 45(2): 289–294.
  • 6. Kumar V, Abbas AK, Fausto N. Robbins and Cotran Pathologic basis of disease. In: Kumar V (ed). Elsevier, Philadelphia 2005: 1085–1088.
  • 7. Marfe G, De Martino L, Tafani M, et al. A multicancer-like syndrome in a dog characterized by p53 and cell cycle-checkpoint kinase 2 (CHK2) mutations and sirtuin gene (SIRT1) down-regulation. Res Vet Sci. 2012; 93(1): 240–245, doi: 10.1016/j.rvsc.2011.07.030, indexed in Pubmed: 21890154.
  • 8. McAloose D, Newton AL. Wildlife cancer: a conservation perspective. Nat Rev Cancer. 2009; 9(7): 517–526, doi: 10.1038/nrc2665, indexed in Pubmed: 19550426.
  • 9. Meuten DJ. Tumors in Domestic Animals. In: Meuten DJ (ed). Wiley-Blackwel, Iowa 2017: 557–558.
  • 10. Panda SK, Nath I, Roy PK, et al. Uterine adenocarcinoma in an indian one-horned rhinoceros (rhinoceros unicornis). Zoos’ Print. 2009; 24(7): 17–19.
  • 11. Rahim A, Ahmad A, Reza K, et al. Uterine adenocarcinoma in a domestic rabbit. GV. 2012; 9(2): 245–247, doi: 10.5829/idosi.gv.2012.9.2.6513.
  • 12. Robert N, Posthaus H. Uterine adenocarcinoma in a captive sika deer. J Wildl Dis. 1999; 35(1): 141–144, doi: 10.7589/0090-3558-35.1.141, indexed in Pubmed: 10073366.
  • 13. Rzymski P, Tomczyk K, Rzymski P, et al. Impact of heavy metals on the female reproductive system. Ann Agric Environ Med. 2015; 22(2): 259–264, doi: 10.5604/12321966.1152077, indexed in Pubmed: 26094520.
  • 14. Sapundzhiev E, Pupaki D, Zahariev P, et al. Fibroleiomyoma in elephant uterus. J Vet Med A Physiol Pathol Clin Med. 2007; 54(9): 499–500, doi: 10.1111/j.1439-0442.2007.00949.x, indexed in Pubmed: 17931224.
  • 15. Serenella P, Roperto F. Spontaneous Uterine Tumors in Three Cats. Vet Path. 1984; 21: 257–258.
  • 16. Thompson R, Armién AG, Rasmussen JM, et al. Uterine adenocarcinoma in a Przewalski’s wild horse (Equus ferus przewalskii). J Zoo Wildl Med. 2014; 45(2): 441–445, doi: 10.1638/2013-0200R1.1, indexed in Pubmed: 25000717.
  • 17. Turan T, Ureyen I, Karalok A, et al. Pulmonary recurrence in patients with endometrial cancer. J Chin Med Assoc. 2016; 79(4): 212–220, doi: 10.1016/j.jcma.2015.10.010, indexed in Pubmed: 26874679.
  • 18. Wilson M, Hermes R, Bainbridge J, et al. A case of metastatic uterine adenocarcinoma in a southern white rhinoceros (Ceratotherium simum simum). J Zoo Wildl Med. 2010; 41(1): 111–114, doi: 10.1638/2009-0128.1, indexed in Pubmed: 20722262.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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