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2013 | 57 | 3 |

Tytuł artykułu

Ghrelin concentration in half-blood jumping horses during moderate and intense training exercise

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The aim of the study was to assess the impact of varying intensity of exercise on ghrelin levels in half-blood jumping horses during training season. Blood samples were collected in the period of intense and moderate exercise. Serum concentrations of active and total ghrelin were measured using commercial RIA kits. Exercise did not cause the disruption in energy homeostasis, which was confirmed by the conducted tests. Total concentration of ghrelin measured during the increased effort intensity elevated in stallions (from 1031.45 to 1732.19 pg/mL at P ≤ 0.05). The opposite situation occurred in the case of active ghrelin, which concentration did not increase significantly in mares (from 26.21 to 28.46 pg/mL), whereas an insignificant decrease was noted in stallions (from 24.19 to 22.54 pg/mL). The only significant difference between stallions and mares was noted in the 2nd sampling (P = 0.015). The research proved that the fluctuations of both studied parameters did not reflect a negative impact of the increased effort.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

57

Numer

3

Opis fizyczny

p.443-447,ref.

Twórcy

  • Department of Animal and Environment Hygiene, University of Life Sciences in Lublin, 20-033 Lublin
autor
  • Department and Clinic of Animal Internal Diseases, University of Life Sciences in Lublin, 20-033 Lublin
  • Department of Animal and Environment Hygiene, University of Life Sciences in Lublin, 20-033 Lublin
autor
  • Department of Animal and Environment Hygiene, University of Life Sciences in Lublin, 20-033 Lublin
  • Department of Animal and Environment Hygiene, University of Life Sciences in Lublin, 20-033 Lublin

Bibliografia

  • 1. Anderson L.L., Jeftinija S., Scanes C.G., Stromer M.H., Lee J.S., Jeftinija K., Glavaski-Joksimovic A.: Physiology of ghrelin and related peptides. Dornest AnimEndocrinol 2005, 29, 111-144.
  • 2. Cummings D.E., Purnell J.Q., Frayo R.S., Schmidova K., Wisse B. E., Weigle D.S.: A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001, 50, 1714-1719.
  • 3. Dall R., Kanaley J., Hansen T.K, Moller N., Christiansen J.S., Hosoda H., Kangawa K., Jorgensen J.O.: Plasma ghrelin levels during exercise in healthy subjects and in growth hormone deficient patients. Europ J Endocrinol 2002, 147, 65-70.
  • 4. Date Y., Kojima M., Hosoda H., Sawaguchi A., Mondal M.S., Suganuma T., Matsukura S., Kangawa K., Nakazato M.: Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 2000, 141, 4255-4261.
  • 5. Gale S.M., Castracane V.D., Mantzoros C.S.: Energy homeostasis, obesity and eating disorders: recent advances in endocrinology. J Nutr 2004, 134, 295-298.
  • 6. Gordon M.E., Mckeever K.H.: Diurnal variation of ghrelin, leptin, and adiponectin in Standardbred mares. J Anim Sci 2005, 83, 2365-2371.
  • 7. Gordon M.E., McKeever K.H., Bokman S., Betros C.L., Manso- Filho H., Liburt N., Streltsova J.: Interval exercise alters feed intake as well as leptin and ghrelin concentrations in Standardbred mares. Equine Vet J Suppl 2006, 36, 596-605.
  • 8. Gordon M.E., Mckeever K.H., Betros C.L., Manso Filho H.C.: Plasma leptin, ghrelin and adiponectin concentrations in young lit racehorses versus mature unfit standardbreds. Vet J 2007. 173, 93-102.
  • 9. Gordon M.E., Mckeever K.H., Betros C.L., Manso Filho H.C.: Exercise-induced alterations in plasma concentrations of ghrelin, adiponectin, leptin, glucose, insulin, and Cortisol in horses. Vet J 2007, 173, 532-540.
  • 10. Haqq A.M., Farooqi I.S., O'Rahilly S., Stadler D.D., Rosenfeld R.G., Pratt K.L., LaFranchi S.H., Purneil J.Q.: Serum ghrelin levels are inversely correlated with body mass index, age, and insulin concentrations in normal children and are markedly increased in Prader-Willi syndrome. J Clin Endocrinol Metab 2003, 88, 174-178.
  • 11. Hagobian T.A., Sharoff C.G., Braun B.: Effects of short-term exercise and energy surplus on hormones related to regulation of energy balance. Metabolism 2008, 57, 393-398.
  • 12. Hansen T.K., Dali R., Hosoda H., Kojima M., Kangawa K., Christiansen J.S., Jorgensen J.O.: Weight loss increases circulating levels of ghrelin in human obesity. Clin Endocrinol 2002, 56, 203-206.
  • 13. Hayashida T., Murakami K., Mogi K., Nishihara M., Nakazato M., Mondai M.S., Horii Y., Kojima M., Kangawa K., Murakami N.: Ghrelin in domestic animals: distribution in stomach and its possible role. Domest Anim Endocrinol 2001, 21, 17 24.
  • 14. Jürimäe J., Hofmann P., Jürimäe T., Palm R, Mäestu J., Purge P., Sudi K., Rom K., von Duvillard S.P.: Plasma ghrelin responses to acute sculling exercises in elite male rowers. Eur J Appl Physiol 2007, 99, 467-474.
  • 15. Kallio, J., Pesonen U., Karvonen M.K., Kojima M., Hosoda H., Kangawa K., Koulu M.: Enhanced exercise-induced GH secretion in subjects with Pro7 substitution in the prepro-NPY. J Clin Endocrinol Metab 2001, 86, 5348-5352.
  • 16. Kędzierski W., Kapica M.: Plasma concentration of leptin and ghrelin in Standardbred foals as related to the age, sex, exercise and training. Animal 2008, 4, 582-587.
  • 17. Kędzierski W., Kowalik S.: Leptin and ghrelin and the indices of lipid metabolism as related to sex steroid hormones in trotters. J Equine Vet Sci 2009, 29, 17-23.
  • 18. Kowalik S., Kędzierski W.: The effect of interval versus continuous exercise on plasma leptin and ghrelin concentration in young trotters. Pol J Vet Sci 2011, 14, 373-378.
  • 19. Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., Kangawa K.: Ghrelin is a growth-hormone releasing acylated peptide from stomach. Nature 1999, 402, 656-660.
  • 20. Leidy H.J., Gardner J.K., Frye B.R., Snook M.L., Schuchert M.K., Richard E.L., Williams N.I.: Circulating ghrelin is sensitive to changes in body weight during a diet and exercise program in normal-weight young women. J Clin Endocrinol Metab 2004, 89, 2659-2664.
  • 21. Lewis, L.D.: Feeding and Care. In: Equine Clinical Nutrition, edited by Williams and Wilkins, Pennsylvania, 1995, pp. 237- 238.
  • 22. Schmidt A., Maier C., Schaller G., Nowotny P., Bayerle-Eder M., Buranyi B., Luger A., Wolzt M.: Acute exercise has no effect on ghrelin plasma concentrations. Horm Metab Res 2004, 36,174-177.
  • 23. Stengel A., Wanga L., Taché Y.: Stress-related alterations of acyl and desacyl ghrelin circulating levels: mechanisms and functional implications. Peptides 2011, 32, 2208-2217.
  • 24. Tschöp M., Weyer C., Tataranni P.A., Devanarayan V., Ravussin E., Heiman M.L.: Circulating ghrelin levels are decreased in human obesity. Diabetes 2001, 50, 707-709.
  • 25. Vestergaard E.T., Dali R., Lange K.H., Kjaer M., Christiansen J.S., Jorgensen J.O.: The ghrelin response to exercise before and after GH administration. J Clin Endocrinol Metab 2007, 92, 297- 303.
  • 26. Yang J., Brown M.S., Liang G., Grishin N.V., Goldstein J.L.: Identification of the acyltransferase that octanoylates ghrelin, an appetite-timulating peptide hormone. Cell 2008, 132, 387-396.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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