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2013 | 20 | 3 |

Tytuł artykułu

The effect of vigorous aerobic and standard anaerobic exercise testing on GH-IGF-1 secretion in adult females

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Introduction. Exercise-associated effects on the GH→IGF-1 axis were studied, mainly following aerobic exercise. Material and Methods. The effects of laboratory vigorous aerobic (10-min treadmill run at 85% of peak VO2 ) and standard all-out anaerobic (30 s Wingate anaerobic test- WAnT) tests on the GH→IGF-1 axis were determined in 12 healthy active females (24-34 years). The tests were performed in random order. Blood samples for GH and IGF-1 were collected before and 20, 30, 40 and 60 minutes after the beginning of each exercise test. Both tests were associated with significant increases in GH. Results. Peak GH was higher following the WAnT (11.0 ± 8.3 vs. 7.5 ± 7.3 ng/ml, respectively) but this difference was not statistically significant. However, the GH area under the curve (AUC) was signifi cantly greater in the anaerobic test as compared with the aerobic test. Only the WAnT was associated with a significant increase in IGF-1 levels (from 177.8 ± 47.2 to 198.8 ± 56.2, p < 0.02). However, no significant differences were found in peak IGF-1 and IGF-1 AUC following both tests. Vigorous aerobic and standard allout anaerobic laboratory tests led to significant GH increases in the same female individuals. GH and IGF-1 responses were greater following the WAnT. Conclusions. GH-IGF-1 changes may be used to gauge exercise intensity, not only following aerobic but also anaerobic exercise.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

20

Numer

3

Opis fizyczny

p.141-146,fig.,ref

Twórcy

autor
  • Child Health and Sports Center, Pediatric Department, Meir Medical Center, Sackler School of Medicine, Tel-Aviv University, Israel
autor
  • Child Health and Sports Center, Pediatric Department, Meir Medical Center, Sackler School of Medicine, Tel-Aviv University, Israel
autor
  • Wingate Institute, The Zinman College of Physical Education and Sport Sciences, Netanya, Israel
  • Child Health and Sports Center, Pediatric Department, Meir Medical Center, Sackler School of Medicine, Tel-Aviv University, Israel
autor
  • Wingate Institute, The Zinman College of Physical Education and Sport Sciences, Netanya, Israel
autor
  • Child Health and Sports Center, Pediatric Department, Meir Medical Center, Sackler School of Medicine, Tel-Aviv University, Israel

Bibliografia

  • 1. Eliakim A, Nemet D, Zaldivar F, McMurray RG, Culler FL, Galassetti P, Cooper DM. Reduced exercise-associated response of the GH-IGF-1 axis and catecholamines in obese children and adolescents. J Appl Physiol. 2006; 100: 1630-1637.
  • 2. Nemet D, Oh Y, Kim HS, Hill MA, Cooper DM. The effect of intense exercise on inflammatory cyotkines and growth mediators in adolescent boys. Pediatrics. 2002; 110: 681-689.
  • 3. Nemet D, Eliakim A. Growth hormone-insulin-like growth factor-1 and inflammatory response to single exercise bout in children and adolescents. Med Sport Sci. 2010; 55: 141-155.
  • 4. Schwarz AJ, Brasel JA, Hintz RL, Mohan S, Cooper DM. Acute effect of brief low- and high-intensity exercise on circulating IGF-1, 2 and IGF binding protein-3 and its proteolysis in young healthy men. J Clin Endocrinol Metab. 1996; 81: 3492-3497.
  • 5. Stokes K, Nevill M, Frystyk J, Lakomy H, Hall G. Human growth hormone response to repeated bouts of sprint exercise with different recovery periods between bouts. J Appl Physiol. 2005; 99: 1254-1261.
  • 6. Meckel Y, Eliakim A, Seraev M, Zaldivar F, Cooper DM, Sagiv M, Nemet D. The effect of a brief sprint interval exercise on growth factors and inflammatory mediators. J Strength Cond Res. 2009; 23: 225-230.
  • 7. Meckel Y, Nemet D, Bar-Sela S, Radom-Aizik S, Cooper DM, Sagiv M, Eliakim A. Hormonal and inflammatory responses to different types of sprint interval training. J Strength Cond Res. 2011; 25: 2161-2169.
  • 8. Adams GR. Autocrine/paracrine IGF-1 and skeletal muscle adaptation. J Appl Physiol. 2002; 93: 1159¬1167.
  • 9. Bar-Or O. The Wingate anaerobic test: An update on methodology, reliability and validity. Sports Med. 1987; 4: 381-394.
  • 10. Felsing NE, Brasel JA, Cooper DM. Effect of low and high intensity exercise on circulating growth hormone in men. J Clin Endocrinol Metab. 1992; 75: 157-162.
  • 11. Pritzlaff CJ, Wideman L, Weltman JY, Abbott RD, Gutgesell ME, Hartman ML, Veldhuis JD, Weltman A. Impact of acute exercise intensity on pulsatile growth hormone release in men. J Appl Physiol. 1999; 87: 498¬504.
  • 12. Sauro, LM Kanaley JA. The effect of exercise duration and mode on the growth hormone responses in young women on oral contraceptives. Eur J Appl Physiol. 2003; 90: 69-75.
  • 13. Eliakim A, Nemet D. Exercise provocation test for growth hormone secretion. Pediatr Exerc Sci. 2008; 20: 370-378.
  • 14. Wideman L, Weltman JY, Shah N, Story S, Veldhuis JD, Weltman A. Effects of gender on exercise-induced growth hormone release. J Appl Physiol. 1999; 87: 1154¬1162.
  • 15. Adams GR. Autocrine/paracrine IGF-1 and skeletal muscle adaptation. J Appl Physiol. 2002; 93: 1159-1167.
  • 16. Frasier SD. A preview of growth hormone stimulation tests in children. Pediatrics. 1974; 53: 929-937.
  • 17. Rosenfeld RG, Albertsson-Wikland K, Cassorla F, Frasier SD, Hasegawa Y, Hintz RL, Lafranchi S, Lippe B, Loriaux L, Melmed S. Diagnostic controversy: the diagnosis of childhood growth hormone deficiency revisited. J Clin Endocrinol Metab. 1995; 80: 1532¬1540.
  • 18. Eliakim A, Nemet D. Exercise training, physical fitness and the growth hormone-insulin-like growth factor-1 axis and cytokine balance. Med Sport Sci. 2010; 55: 128¬140.
  • 19. Vettor R, Macor C, Rossi E, Piemonte G, Federspil G. Impaired counterregulatory hormonal and metabolic response to exhaustive exercise in obese subjects. Acta Diabetol. 1997; 34: 61-66.
  • 20. Kanaley JA, Weatherup-Dentes MM, Jaynes EB, Hartman ML. Obesity attenuates the growth hormone response to exercise. J Clin Endocrinol Metab. 1999; 84(9): 3156-3161.

Typ dokumentu

Bibliografia

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