Inhibition of lactophage activity by quinolinilporphyrin and its zinc complex

• Autorzy: Vodzinska N. , Galkin B. , Ishkov Y. , Kirichenko A. , Kondratyuk A. , Filipova T.
• Języki publikacji: EN

Abstrakty

EN

The influence of free base of quinolinilporphyrin and its Zn complex on infectivity of lactophages E3, E5 and E17 has been studied. The results of our investigations show that inhibition of lactophage activity by Zn complex of quinolinilporphyrin at concentration 10 μM and 20 μM was in the range 53–62% and 65–85%, respectively. The presence of this porphyrin in nutrient medium prevents the propagation of bacteriophage infection in Lactococcus lactis, but does not affect the phage adsorption process. The free base of quinolinilporphyrin slightly inhibits the activity of lactophages.

Słowa kluczowe

EN

inhibition; lactophage activity; quinolinilporphyrin; zinc complex; Lactococcus lactis; lactophage

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2011
• Tom: 60
• Numer: 3
• Opis fizyczny: p.229-232,fig.,ref.

Twórcy

autor

Vodzinska N.

• Biotechnological Scientific-Educational Centre, I.I. Mechnikov Odessa National University, str.Dovzhenko 7a, 65-58 Odessa, Ukraine

autor

Galkin B.

autor

Ishkov Y.

autor

Kirichenko A.

autor

Kondratyuk A.

autor

Filipova T.

Bibliografia

• Coffey A. and R.P. Ross. 2002. Bacteriophage-resistance systems in dairy starter strains: molecular analysis to application. Antonie van Leeuwenhoek 82: 303–321.
• Cowsert L.M. 1994. Treatment of papillomavirus infections: recent practice and future approaches. Intervirology 37: 226–230.
• Duwat P., S. Sourice, B. Cesselin, G. Lamberet, K. Vido, P. Gaudu, Y. Le Loir, F. Violet, P. Loubière and A. Gruss. 2001. Respiration capacity of the fermenting bacterium Lactococcus lactis and its positive effects on growth and survival. Journal of Bacteriology. 183: 4509–4516.
• Grandadam M., D. Ingrand and J.M. Huraux. 1995. Photodynamic inactivation of cell-free HIV strains by a red absorbing chlorin-type photosensitizer. Journal of Photochemistry and Photobiology B: Biology 31: 171–177.
• Krulko I.V., A.V. Kharina, N.S. Vodzinska, T.O. Filipova and V.P. Polischuk. 2008. Antifitoviral activity of synthetic porphyrins in system in vivo. Ukrainian journal of agroecology. Spec. issue: 138–139.
• Krulko I.V., S.A. Zaika, A.V. Kharina, N.S. Vodzinska and V.P. Polischuk. 2009. Porphyrins as the inhibitors of viral infection in plant tissue culture. Microbiology & Biotechnology 2: 47–52.
• Kutter Elizabeth and Alexander Sulakvelidze (eds). 2005. Bacteriophages : biology and applications. CRC Press, Boca Raton – London – New York – Washington.
• Nitzan Y., H.M. Wexler and S.M. Finegold. 1994. Inactivation of anaerobic bacteria by various photosensitized porphyrins or by hemin. Current Microbiology 29: 125–131.
• North J., H. Neyndorff and J.G. Levy. 1993. Photosensitizers as virucidal agents. Journal of Photochemistry and Photobiology B: Biology. 17: 99–108.
• Pasternack R.F., E.J. Gibbs and J.J. Villafranca. 1983. Interactions of porphyrins with nucleic acids. Biochemistry 22: 2406–2414.
• Philippova T.O., B.N. Galkin, O.Yu. Zinchenko, M.Yu. Rusakova, V.A. Ivanitsa, Z.I. Zhilina, S.V. Vodzinskij and Yu.V. Ishkov. 2003. The antimicrobial properties of new synthetic porphyrins. Journal of Porphyrins and Phthalocyanines 11–12: 737–742.
• Ramezani M., J. Behravan, M. Arab and S. Amel Farzad. 2008. Antiviral activity of Euphorbia helioscopia extract. Journal of Biological Sciences 8: 809–813.
• Terzaghi, B.E. and W.E. Sandine. 1975. Improved medium for lactic streptococci and their bacteriophages. Applied Microbiology 29: 807–813.
• Vodzinska N.S., T.O. Filipova, B.M. Galkin, Yu.V. Ishkov and G.M. Kirichenko. 2008. Staphylococcal bacteriophage inactivation in the presence of synthetic porphyrins. Microbiology & Biotechnology 3: 82–88.
• Zupan K., L. Herenyi, K. Toth, Z. Majer and G.G. Csık. 2004. Binding of cationic porphyrin to isolated and encapsidated viral DNA analyzed by comprehensive spectroscopic methods. Biochemistry 43: 9151–9159.