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2011 | 55 | 3 |
Tytuł artykułu

Analysis of expression of AIF and PARP-1 in cancerogenesis of HPV-positive cervix

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Języki publikacji
The mRNA expression of AIF and PARP-1 in HPV negative non-tumour epithelial cells and HPV-positive cervical cancer cells using the real-time PCR method was examined. An increased level of AIF and PARP-1 mRNA in cervical cancer cells in comparison to normal epithelial cells was demonstrated. These results suggest that changes in the mRNA expression level of AIF and PARP-1 might be involved in cervical cancer development. The analysis of these two factors may represent a new molecular tool for cervical cancer prevention in women with HPV persistent infection.
Opis fizyczny
  • Department of Molecular Virology, Adam Mickiewicz University, 61-614 Poznan, Poland
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