Changes in gut microbiota in children with atopic dermatitis administered the bacteria Lactobacillus casei DN – 114001

• Autorzy: Klewicka E. , Cukrowska B. , Libudzisz Z. , Slizewska K. , Motyl I.
• Języki publikacji: EN

Abstrakty

EN

Gut microbiota was analyzed in children, aged 6–18 months and su$ering from atopic dermatitis before and after 3 month supplementation of their diet with Lactobacillus casei DN – 114001 in a dose of 10⁹ cells daily. On completion of this period the total number of fecal Lactobacillus sp. cells decreased from 7.86 Log₁₀ CFU/g to 6.40 Log₁₀ CFU/g. After the next 5 months (without dietary supplementation with the probiotic bacteria) the level of Lactobacillus sp. cells was maintained at the latter value. During the dietary supplementation with the probiotic strain, the level of Bifidobacterium cells was maintained at 6.15–6.89 Log₁₀ CFU/g while after 5 months it decreased to 5.57 Log₁₀ CFU/g. The population of Clostridium sp. was reduced after 3 months of dietary supplementation from 6.49 to 5.83 Log₁₀ CFU/g and was maintained at the latter level during the next 5 months. The dietary supplementation had no effect on populations of Bacteroides sp., Enterococcus sp. and Enterobacteriaceae. Supplementation of children who developed atopic dermatitis with the preparation of Lactobacillus casei DN – 114001 positively affected their gut microbiota in terms of bifidobacteria and clostridia populations.

Słowa kluczowe

EN

gut; child; atopic dermatitis; dermatitis; bacteria; Lactobacillus casei; human disease; allergic disease; diet supplementation; prevalence; microorganism; gastrointestinal tract; microflora change

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2011
• Tom: 60
• Numer: 4
• Opis fizyczny: p.329-333,ref.

Twórcy

autor

Klewicka E.

• Institute of Fermentation Technology and Microbiology, Technical University of Lodz, 171/173 Wilczanska St., 90-924 Lodz, Poland

autor

Cukrowska B.

autor

Libudzisz Z.

autor

Slizewska K.

autor

Motyl I.

Bibliografia

• Adlerberth I., D.P. Strachan, P.M. Matricardi, S. Ahrne, L. Orfei, N. Aberg, M.R. Perkin, S. Tripodi, B. Hesselmar, R. Saalman and others. 2007. Gut microbiota and development of atopic eczema in 3 European birth cohorts. J. Allergy Clin. Immun. August: 343–350.
• De Meer G., N.A. Janssen and B. Brunekreef. 2005. Early childhood environment related to microbial exposure and the occurrence of atopic disease at school age. Allergy 60: 619–625.
• Cukrowska B. 2008. Microbiotic theory of developing allergies – the role of probiotics in the activation of anti-allergic processes. (in Polish). Zakażenia 5: 245–253.
• Favier C., E.E. Vaughan, W.M. De Vos and A. Akkermans. 2002. Molecular monitoring of succession of bacterial communities in human neonates. Appl. Environ. Microb. 68: 219–226.
• Garrido D., A. Suau, P. Pochart, S. Cruchet and M. Gotteland. 2005. Modulation of the fecal microbiota by the intake of the Lactobacillus johnsonii La1 – containing product in human volunteers. FEMS Microbiol. Lett. 284: 249–256.
• Harmsen H.J., A.C. Wildeboer-Veloo, G.C. Raangs, A.A. Wagendrop, N. Klijn, J.G. Bindels and G.W. Welling. 2000. Analysis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection methods. J. Pediatr. Gastr. Nutr. 30: 61–67.
• Hartemink R., B.J. Kok, G.H. Weenk and F.M. Rombous. 1996. Raffinose – Bifidobacterium (RB) agar, a new selective medium for bifidobacteria. J. Microbiol. Meth. 27: 33–43.
• Kalliomaki M., P. Kirjavainen, E. Eerola, P. Kero, S. Salminen and E. Isolauri. 2001. Distinct patterns of neonatal gut microflora in infants developing or not developing atopy. J. Allergy Clin. Immun. 107: 129–134.
• Kelly D., T. King and R. Aminov. 2007. Importance of microbial colonization of the gut in early life to the development of immunity. Mut. Res. 622: 58–69.
• Kirjavainen P., E. Apostolou, T. Arvola, S.J. Salminen, G.R. Gibson and E. Isolauri. 2001. Characterizing the composition of intestinal microflora as a prospective treatment target in infant allergic disease. FEMS Immunol. Med. Micr. 32: 1–7.
• Klewicka E., Z. Zduńczyk and J. Juśkiewicz. 2009. Effect of lactobacillus fermented beetroot juice on composition and activity of cecal microflora of rats. Eur. Food Res. Technol. 229: 153–157.
• Leung A.K.C., K.L.E. Hon and L.M. Robson. 2007. Atopic dermatitis. Adv. Pediat. 54: 241–273.
• Ouwehand A., E. Isolauri and S. Salminen. 2002. The role of the intestinal microflora for the development of the immune system in early childhood. Eur. J. Nutr. 41 [Suppl 1]: I32–I37.
• Remes S.T., K. Tivanainen, H. Koskela and J. Pekkanen. 2003. Which factors explain the lower prevalence of atopy amongst farmers’ children? Clin. Exp. Allergy 33: 427–434.
• Rinne M., M. Kalliomaki, H. Arvilommi, S. Salminen and E. Isolauri. 2005. Effect of probiotics and breastfeeding on the Bifidobacterium and Lactobacillus/Enterococcus microbiota and humoral immune responses. J. Pediat. 186–191.
• Rocha F.C.A. 2006. Protective role of helminthiasis in the development of autoimmune diseases. Clin. Dev. Immunol. 13(2–4): 159–162.
• Salminen S., C. Bouley, M.C. Bourton-Ruault, J.H. Cummings, A. Franck, G.R. Gibson, E. Isolauri, M.C. Moreau, M. Roberfroid, and I. Rowland. 1998. Functional food science and gastrointestinal physiology and function. Brit. J. Nutr. 80: 147–171.
• Schell M.A., M. Karmirantzou, D. Vilanova, B. Berger, G. Pessi, M.C. Zwahlen, F. Desiere, P. Brok, M. Delley, R.D. Pridmore and others. 2002. The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract. Proc. Natl. Acad. Sci. USA 99: 14422–14427.
• Strachan D.P. 1989. Hay, fever, hygiene and household size. Brit. Med. J. 299: 1259–1260.