PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2010 | 54 | 4 |

Tytuł artykułu

Assessment of pruritus using pruritus score test in dogs with atopic dermatitis treated with cyclosporine or prednisone

Autorzy

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The purpose of this study was to evaluate the suitability of pruritus score test in pruritus diagnosis in dogs. The test was used to assess the frequency and severity of pruritus in dogs between 1 and 3 years of age, suffering from atopic dermatitis. Skin pruritus was assessed: during the first visit (examination 0), after elimination of secondary dermatosis (examination 1), 2 weeks after the treatment with prednisone - group I-E or cyclosporine - group II-C (examination 2) as well as 6 weeks after treatment (examination 3). In examination 0, the skin pruritus in all dogs was scored at 26.75%. Reduction of pruritus was observed during the treatment in examination 3 in dogs of group I-E (by 80.46%) and in dogs of group II-C (by 86.12%) in comparison with examination 0. Localisation of pruritus in particular body parts was also examined, resulting in observation that in examination 0 it was mostly found in interdigital space of front paws, facial part of the muzzle, chin, ears but not always with the same intensity in symmetrically placed body parts. Mean values of the measurement were statistically significant (P≤0.005) after 2, 4, and 6 weeks of the treatment in I-E and II-C groups. No statistically significant differences were observed between I-E and II-C groups in consecutive measurements.

Wydawca

-

Rocznik

Tom

54

Numer

4

Opis fizyczny

p.687-692,ref.

Twórcy

autor
  • Sub-department of Clinical Diagnostics and Veterinary Dermatology, Department and Clinic of Internal Medicine, Faculty of Veterinary Medicine, Uniersity of Life Sciences in Lublin, 20-62 Lublin, Poland

Bibliografia

  • 1. Burton G., Burrows A., Walker R., Robson D., Basset R., Bryden S., Hill S.: Efficacy of cyclosporine in the treatment of atopic dermatitis in dogs- combined results from two veterinary dermatology referral centers. Austr Vet J 2004, 82, 681-685.
  • 2. Carlotti D., Madiot G., Ducret J., Jasmin P., Gardey L.: Use of recombinant omega interferon therapy in canine atopic dermatitis: a pilot study. Vet Dermatol 2004, 15 (Suppl. 1), 32.
  • 3. Duo L.J.: Electrical needle therapy of uremic pruritus. Nephron 1987, 47, 179-183.
  • 4. Elman S., Hynan L.S., Gabriel V., Mayo M.J.: The 5-D itch scale: a new measure of pruritus. Brit J Dermatol 2009, 10, 1-7.
  • 5. Favrot C., Linek M., Mueller R., Zini E.: For the international task force on canine atopic dermatitis: development of a questionnaire to a assess the impact of atopic dermatitis on health-related quality of life of affected dogs and their owners. Vet Dermatol 2010, 21, 64-70.
  • 6. Favrot C., Steffan J., Seewald W., Picco F.: A prospective study on the clinical features of chronic canine atopic dermatitis and its diagnosis. Vet Dermatol 2010, 21, 23-31.
  • 7. Germain P.A., Prelaud P., Bensignor E.: CADESI (canine atopic dermatitis extent and severity index) reproducibility. Revue Med Vet 2005, 156, 382-385.
  • 8. Hill P.B., Lau P., Rybnicek J.: Development of an owner assessed scale to measure the severity of pruritus in dogs. Vet Dermatol 2007, 18, 301-308.
  • 9. Ikoma A., Steinhoff M., Stander S., Yosipovitch G., Schmelz M.: The neurobiology of itch. Nat Rev Neurosci 2006, 7, 535-547.
  • 10. Krajnik M., Żylisz Z.: Pruritus in advanced internal diseases. Pathogenesis and treatment. Pol Med Paliatyw 2002, 12, 71-82.
  • 11. Miller W.H., Scott D.W, Wellington J.R.: Investigations on the antipruritic effects of ascorbic acid given alone and in combination with a fatty acid supplement to dogs with allergic skin disease. Canine Pract 1992, 17, 11-13.
  • 12. Nuttal T., McEwan N.: Objective measurement of pruritus in dogs: a preliminary study using activity monitors. Vet Dermatol 2006, 17, 348-351.
  • 13. Olivry T., Guaguere E., Heripret D.: Treatment of canine atopic dermatitis with misoprostol, a prostaglandin E1 analogue: an open study. J Dermatol Treat 1997, 8, 243- 247.
  • 14. Olivry T.: The American College of Veterinary Dermatology Task Force on canine atopic dermatitis. Elsevier Science B.V., Amsterdam, 2001, pp. 143-276.
  • 15. Olivry T., Sousa C.A.: The ACVD task force on canine atopic dermatitis (XIX): general principles of therapy. Vet Immunol Immunopathol 2001, 81, 311-316.
  • 16. Olivry T., Rivierre C., Jackson H.A., Murphy K.M., Davidson G., Sousa A:. Cyclosporine decreases skin lesions and pruritus in dogs with atopic dermatitis: a blinded randomized prednisolone-controlled trial. Vet Dermatol 2002, 13, 77-87.
  • 17. Olivry T., Mueller R.S.: Evidence-based veterinary dermatology: a systematic review of pharmacotherapy of canine atopic dermatitis. Vet Dermatol 2003, 14, 121-146.
  • 18. Olivry T., Foster A. P., Mueller R. S., McEwan N., Chesney C., Williams H.C.: Interventions for atopic dermatitis in dogs: a systemic review of randomized controlled trials. Vet Dermatol 2010, 21, 4-22.
  • 19. Prelaud P., Guaguere E., Alhaidari Z.: Re-evaluation of diagnostic criteria of canine atopic dermatitis. Rev Med Vet 1998, 149, 1057-1064.
  • 20. Rybnicek J., Lau-Gillard P.J., Harvey R., Hill P.B.: Further validation of pruritus severity scale for use in dogs. Vet Dermatol 2008, 20, 115-122.
  • 21. Scott D., Miller W., Griffin C.: Muller & Kirk's Small Animal Dermatology. W.B. Saunders Comp., Philadelphia, USA, 2001, pp. 574-601.
  • 22. Stander S., Weisshaar E., Mettang T., Szepietowski J., Carstein E., Ikoma A., Bergasa N., Gieler U., Misety L., Wallengren J.: Clinical classification of itch: a position paper of International Forum for the Study of Itch. Acta Dermatol Venereol 2007, 87, 291-294.
  • 23. Steffan J., Alexander D., Brovedani F., Fisch R.: Comparison of cyclosporine with methylprednisolone for treatment of canine atopic dermatitis: a blinded randomized trial. Vet Dermatol 2003, 14, 34-46.
  • 24. Steffan J., Horn J., Gruet P., Strehlau G., Fondati A., Ferrer L., Noli C.: Remission of the clinical signs of atopic dermatitis in dogs after cessation of treatment with cyclosporine A or methylprednisolone. Vet Rec 2004, 154, 681-684.
  • 25. Steffan J., Favrot C., Mueller R. A.: Systematic review and meta-analysis of the efficacy and safety of cyclosporine for the treatment of atopic dermatitis in dogs. Vet Dermatol 2006, 17, 3-16.
  • 26. Teresiak-Mikołajczak E., Czarnecka-Operacz M., Silny W.: Updated knowledge on aetiopathogenesis and therapy of pruritus in chronic inflammatory dermatoses. Postępy Dermatolog Alergolog XXVI, 2009, 1, 56-64.
  • 27. Teresiak-Mikołajczak E., Czarnecka-Operacz M.: Substance P, vasoactive intestinal peptide and nerve growth factor involvement in the pathogenesis of few dermatoses. Postępy Dermatol Alergol XXII, 2005, 4, 183-188.
  • 28. Toyoda M., Nakamura M., Makino T.: Nerve growth factor and substance P are useful plasma marker of disease activity in atopic dermatitis. Br J Dermatol 2002, 147, 71-79.
  • 29. Twycross R., Greaves M.W., Handwerker H.: Itch: scratching more than the surface. QJM Inter J Med 2003, 96, 7-26.
  • 30. Willemse T.: Investigation of symptomatology and the significance of immediate skin test reactivity in canine atopic dermatitis. Res Vet Sci 1984, 34, 261-266.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.dl-catalog-239799a3-74ee-497a-ade7-3c655157b859
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.