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2010 | 51 | 3 |

Tytuł artykułu

Chromosomal assignment of R-spondin genes in the donkey (Equus asinus, 2n equals 62)

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
R-spondins constitute a recently discovered small family of growth factors, and the evidence of their role in several developmental pathways is growing fast. In this work we describe the chromosomal location of the four RSPO genes in the donkey. Using horse BACs, we localized RSIPO1 on EAS 5q23, RSPO2 on EAS 12q13, RSPO3 on EAS 24q26, and RSPO4 on EAS 15p13. Moreover, RSPO2, RSPO3, and RSPO4 are the first genes mapped on donkey chromosomes 12, 24, and 15, respectively.

Wydawca

-

Rocznik

Tom

51

Numer

3

Opis fizyczny

p.319-321,fig.,ref.

Twórcy

  • Universitta di Milano, Dipartimento di Scienze Animali, Sezione di Zootecnica Agraria, Via Celoria 2, 20133 Milano, Italy
autor
  • National Research Council (CNR), ISPAAM, Laboratory of Animal Cytogenetics and Gene Mapping, Naples, Italy
  • Department of Animal Production, Faculty of Agricultural Science, University of Bari, Bari, Italy
autor
  • National Research Council (CNR), ISPAAM, Laboratory of Animal Cytogenetics and Gene Mapping, Naples, Italy
  • National Research Council (CNR), ISPAAM, Laboratory of Animal Cytogenetics and Gene Mapping, Naples, Italy
autor
  • Universitta di Milano, Dipartimento di Scienze Animali, Sezione di Zootecnica Agraria, Via Celoria 2, 20133 Milano, Italy
autor
  • National Research Council (CNR), ISPAAM, Laboratory of Animal Cytogenetics and Gene Mapping, Naples, Italy
autor
  • Universitta di Milano, Dipartimento di Scienze Animali, Sezione di Zootecnica Agraria, Via Celoria 2, 20133 Milano, Italy

Bibliografia

  • Aoki M, Mieda M. Ikeda T, Hamada Y, Nakamura H, Okamoto H, 2007. R-spondin3 is required for mouse placental development. Dev Biol 301: 218-226.
  • Blaydon DC, Ishii Y, O'Toole EA, Unsworth HC, Teh MT, Rüschendorf F, et al. 2006. The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia. Nat Genet 38: 1245-1247.
  • Bugno M, Klukowka-Rötzler J, Slota E, Witarski W, Gerber V, Leeb T, 2007. Fluorescent in situ hybridization mapping of the epidermal growth factor receptor gene in donkey. J Anim Breed Genet 124: 172-174.
  • Bugno M, Slota E, Witarski W, Gerber V, Klukowska-Roetzler J, 2009. Interleukin 4 receptor alpha (IL4R) and calcium-activated chloride channel 1 (CLCA1) genes map to donkey chromosome. Hereditas 146: 118-121.
  • Chassot AA, Ranc F, Gregoire EP, Roepers-Gajadien HL, Taketo MM, Camerino G, et al. 2008. Activation of beta-catenin signaling by Rspo 1 controls differentiation of the mammalian ovaiy. Hum Mol Genet 17: 1264-1277.
  • De Lorenzi L, Lear TL, Molteni L, Parma P, 2007. The RSPO genes: chromosomal assignment in horse by FISH. Anim Genet 39: 86-87.
  • Di Meo GP, Perucatti A, Peretti V, Incarnato V, Ciotola F, Liotta L, et al. 2009. The 450-band resolution G- and R-banded standard karyotype of the donkey (Equus asinus, 2n=62). Cytogenet Genome Res 125: 266-271.
  • Iannuzzi L, Di Berardino D, 2008. Tools of the trade: diagnostics and research in domestic animal cytogenetics. J Appl Genet 49: 357-356.
  • Kim KA, Zhao J, Andarmani S, Kakitani M, Oshima T, Binnerts ME, et al. 2006. R-Spondin proteins: a novel link to beta-catenin activation. Cell Cycle 5: 23-26.
  • Parma P, Radi O, Vidal V, Chaboissier MC, Dellambra E, Valentini S, et al. 2006. R-spondinl is essential in sex determination, skin differentiation and malignancy. Nat Genet 38: 1304-1309.
  • Raudsepp T, Kijas J, Godard S, Guérin G, Andersson L, Chowdhary BP, 1999. Comparison of horse chromosome 3 with donkey and human chromosomes by cross-species painting and heterologous FISH mapping. Mamm Genome 10: 277-282.
  • Raudsepp T, Mariat D, Guérin G, Chowdhary BP, 2001. Comparative FISH mapping of 32 loci reveals new homologous regions between donkey and horse karyotypes. Cytogenet Cell Genet 94: 180-185.
  • Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, et al. 2009. Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun 381: 453-458.
  • Zabek T, Bugno M, Klukowska-Rötzler J, Gerber V, Słota E, 2009. Chromosomal assignment of equine genes involved in the development of skeletal, gastrointestinal, cardiovascular and nervous system. Hereditas 146: 177-179.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.dl-catalog-19428b12-cdad-404e-ae12-e13b52560202
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