PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2010 | 54 | 4 |

Tytuł artykułu

Evaluation of selected indicators of immune response (IL-1B, IL-4, IL-6, SAA and HP) in pigs fed diets containing deoxynivalenol, T-2 toxin, and zearalenone

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The objective of this study was to examine the clinical significance of selected indicators of immune response (IL-lß, 1L-4, IL-6. SAA, and Hp) in short-term combined intoxication exposure of pigs to low doses of deoxynivalenol, T-2 toxin, and zearalenone present in naturally contaminated feedstuffs during grain growth. Statistically significant differences were not noted after 14 d of feeding diets contaminated with the above mycotoxins. The mycotoxins did not induce inflammatory processes. The subclinical form of combined mycotoxicosis could be due to incorrect immunological response. The identification of the underlying cause would support the development of new methods for the prevention of combined mycotoxicosis.

Wydawca

-

Rocznik

Tom

54

Numer

4

Opis fizyczny

p.631-635,fig.,ref.

Twórcy

autor
  • Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-718 Olsztyn, Poland
autor
autor
autor
autor

Bibliografia

  • 1. Bondy G.S., Pestka J.J.: Immunomodulation by fungal toxins. J Toxicol Environ Health B 2000, 2, 109-143.
  • 2. Bouhet S., Oswald I.P.: The effects of mycotoxins, fungal food contaminants, on the intestinal epithelial cell-derived innate immune response. Vet Immunol Immunopathol 2005, 108, 199-209.
  • 3. Cetin Y., Bullerman L.B.: Cytotoxicity of Fusarium mycotoxins to mammalian cell cultures as determined by the MTT bioassay. Food Chem Toxicol 2005, 43, 755- 764.
  • 4. Gajęcka M., Jakimiuk E., Zielonka Ł., Gajęcki, M.: The biotransformation of chosen the mycotoxins. Pol J Vet Sci 2009, 12, 293-303.
  • 5. Gajęcki M., Zielonka Ł., Obremski K., Jakimiuk E., Gajęcka M.: Multi-mycotoxicosis. Environ Biotechnol 2007, 1, 25-29.
  • 6. Hardin B.D., Robbins C.A., Payam F., Kelman B.J.: The concentration of no toxicological concern (CoNTC) and airborne mycotoxins. J Toxicol Environ Health A 2009, 72, 585-598.
  • 7. Inadera H.: The immune system as a target for environmental chemicals: Xenoestrogens and other compounds. Toxicol Lett 2006, 164, 191-206.
  • 8. Kinser S., Jia Q., Li M., Laughter A., Cornwell P.D., Corton J.C., Pestka J.J.: Gene expression profiling in spleens of deoxynivalenol-exposed mice: Immediate early genes as primary targets. J Toxicol Environ Health A 2004, 67, 1423-1441.
  • 9. Kostro K., Gliński Z., Wojcicka-Lorenowicz K., Krakowski L.: Acute-phase proteins as indicators of diseases in animals. Medycyna Wet 2001, 57, 539-544.
  • 10. Nowicki M., Ostalska-Nowicka D., Miskowiak B.: In vitro substance P-dependent induction of bone marrow cells in common (CD10) acute lymphoblastic leukemia. Leukemia Res 2008, 32, 97-102.
  • 11. Obremski K., Zielonka Ł., Gajęcka M., Jakimiuk E., Bakuła T., Baranowski M., Gajęcki M.: Histological estimation of gilts small intestine wall after administration of feed containing deoxynivalenole, T-2 toxin and zearalenone. Pol J Vet Sci 2008, 11, 339-345.
  • 12. Pallarés F.J., Martínez-Subiela S., Seva J., Ramis G., Fuentes P., Bernabé A., Muñoz A., Cerón J.J.: Relationship between serum acute phase protein concentrations and lesions in finishing pigs. Vet J 2008, 177, 369-373.
  • 13. Piñeiro C., Piñeiro M., Morales J., Andrés M., Lorenzo E., del Pozo M., Alava M.A., Lampreave F.: Pig-MAP and haptoglobin concentration reference values in swine from commercial farms. Vet J 2009, 179, 78-84.
  • 14. Pinton P., Accensi F., Beauchamp E., Cossalter A.M., Callu P., Grosjean F., Oswald I.P.: Ingestion of deoxynivalenol (DON) contaminated feed alters the pig vaccinal immune response. Toxicol Lett 2008, 177, 215- 222.
  • 15. Swamy H.V., Smith T.K., MacDonald E.J.: Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on brain regional neurochemistry of starter pigs and broiler chickens. J Anim Sci 2004, 82, 2131-2139.
  • 16. Tiemann U., Brüssow K.P., Dannenberger D., Jonas L., Pöhland R., Jäger K., Dänicke S., Hagemann E.: The effect of feeding a diet naturally contaminated with deoxynivalenol (DON) and zearalenone (ZON) on the spleen and liver of sow and fetus from day 35 to 70 of gestation. Toxicol Lett 2008, 179, 113-117.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.dl-catalog-18250e1b-6b33-4c80-b7b3-4ca2fa7837e7
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.