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Wydawca
-
Czasopismo
Cellular and Molecular Biology Letters
Rocznik
2001
Tom
06
Numer
2B
Identyfikatory
Okładka
Zawartość wolumenu
2B
artykuł:
p38 MAP kinase inhibitors: from biochemical tools to clinical trials
(
Adams J. L.
,
Bower M. J.
,
Boehm J. C.
,
Gallagher T. F.
,
Hall R.
,
Zhao B.
,
Lee J. C.
), s. 450-451
artykuł:
Protein kinase inhibitors and antibiotic resistance
(
Berghuis A. M.
), s. 452
artykuł:
Structural aspects of protein kinase control
(
Engh R. A.
,
Bossemeyer D.
), s. 453
artykuł:
How to cure diabetes without causing cancer
(
Cohen P.
), s. 454-455
artykuł:
Chemical approaches to protein phosphorylation
(
Cole P. A.
), s. 456
artykuł:
Small molecule irreversible inhibitors of the erbB family of transmembrane receptors
(
Danny W. A.
), s. 457
artykuł:
Highly specific and membrane permeant peptide inhibitors of cGMP-dependent protein kinase Ialpha
(
Dostmann W. R. G.
,
Nickl C. K.
,
Taylor M. S.
,
Brayden J. E.
,
Frank R.
,
Tegge W. J.
), s. 458
artykuł:
Protein kinases as targets for anticancer agents: from inhibitors to useful drugs
(
Fabbro D.
), s. 459-461
artykuł:
EGFR kinase inhibitors: it's role in diverse diseases
(
Frost P.
), s. 462
artykuł:
Inhibition and activation of c-Src: the head and tail of a coin
(
Fukami Y.
), s. 463-464
artykuł:
Use of protein kinase inhibitors to dissect the regulation of protein kinase B [PKB-Akt] by upstream kinases
(
Hill M. M.
,
Andjelkovic M.
,
Brazil D. P.
,
Ferrari S.
,
Fabbro D.
,
Hemmings B. A.
), s. 465
artykuł:
Molecular recognition and active site structure in phosphorelay signal transduction
(
Hoch J. A.
), s. 466
artykuł:
Establishment of binding assay for protein kinase C [PKC] isozymes using synthetic C1 peptides and development of new medicinal leads with PKC isozyme and C1 domain selectivity
(
Irie K.
), s. 467-469
artykuł:
Structure based design of a potent inhibitor of CDK2
(
Davies T. G.
,
Endicott J. A.
,
Johnson L. N.
,
Noble M. E. M.
,
Arris C. E.
,
Bentley J.
,
Calvert A. H.
,
Curtin N. J.
,
Golding B. T.
,
Griffin R. J.
,
Hardcastle I. H.
,
Mesguiche V.
,
Newell H.
,
Parsons R. J.
,
Whitfield H. J.
,
Boyle T.
,
Jewsbury P.
), s. 470
artykuł:
Genome wide screening for inhibitors of protein kinases
(
McCraith S. M.
,
Kahn M.
), s. 471
artykuł:
From consensus sequence to high affinity ligands: acquisition of signaling protein modulators
(
Lawrence D.
), s. 472
artykuł:
Pathological angiogenesis: molecular aspects and therapeutic inhibition of endothelial receptor tyrosine kinases
(
Marme D.
), s. 473-475
artykuł:
Pharmacological manipulation of Rho-associated kinase, ROCK
(
Narumiya S.
), s. 476
artykuł:
Docking interactions in the map kinase cascades
(
Tanoue T.
,
Nishida E.
), s. 477
artykuł:
Cyclin dependent kinases as potential therapeutic target for stroke
(
Park D. S.
), s. 478
artykuł:
Structural basis for the activity of pp60 c-src protein tyrosite kinase inhibitors
(
Pettitt M.
), s. 479
artykuł:
Structural basis for selective inhibitors of protein kinase CK2 by ATP site-directed ligands
(
Sarno S.
,
Battistutta R.
,
de Moliner E.
,
Meggio F.
,
Zanotti G.
,
Pinna L. A.
), s. 480-481
artykuł:
GSK-3: A common target of extracellular stimuli and selective small molecule inhibitors that modulate glycogen metabolism and neuronal death
(
Reith A. D.
), s. 482
artykuł:
Novel and specific Rho-kinase inhibitor, H1152P, directed against the Rho-kinase involved pathway
(
Sasaki Y.
,
Ikenoya M.
,
Yamamoto N.
,
Suzuki M.
,
Hidaka H.
), s. 483
artykuł:
Discovery of substrates and small molecule inhibitors for a death associated protein kinase
(
Valentza A. V.
,
Schumacher A. M.
,
Weiss C.
,
Sawkar A.
,
Zasadzki M.
,
Haiech J.
,
Egli M.
,
Watterson D. M.
), s. 484-485
artykuł:
Designing specific protein kinase inhibitors: insights from computer simulations and comparative sequence-structure analysis
(
Wong C. F.
), s. 486
artykuł:
Modulation of protein kinase signaling by protein phosphatases inhibitors
(
Zhang Z.-Y.
), s. 487-488
artykuł:
Biochemical and functional analysis of STK during head regeneration in hydra
(
Cardenas M. M.
,
Fabila Y.
,
Salgado L. M.
), s. 490
artykuł:
Extracellular signal-regulated kinase 1-2 is defense mechanism for neutrons exposed to DNA-damage
(
Gozdz A.
,
Chlystun M.
,
Hetman M.
), s. 491
artykuł:
Natural versus synthetic genistein in a drug development perspective
(
Grynkiewicz G.
), s. 492-493
artykuł:
Glycogen synthase kinase-3beta as a target for anti-apoptotic signals
(
Hetman M.
,
Kaleta A.
,
Chlystun M.
,
Higgins M.
,
Cavanaugh J.
,
Xia Z.
), s. 494
artykuł:
Inibition of Lyn kinase potentiates BCR-mediated signaling and proliferation
(
Jakies S.
,
Lukas S.
,
Castle B.
,
Snow R.
,
Moss N.
,
Kehry M.
), s. 495
artykuł:
Phosphorylation of calcyclin binding protein [CacyBP]
(
Jastrzebska B.
,
Filipek A.
,
Kuznicki J.
), s. 496
artykuł:
Effect of inhibitors of polypeptide growth factor receptor tyrosine kinase on ATP synthesis in plasma membranes of human malignant tumors
(
Demidova V. S.
,
Globa A. G.
,
Karelin A. A.
), s. 497
artykuł:
Effect of fibrates on branched chain alpha-ketoacid dehydrogenase [BCKDH] kinase activity
(
Knapik-Czajka M.
,
Cyganek I.
,
Wolkow P.
,
Jaskiewicz J.
), s. 498-499
artykuł:
Solvent behavior in the molecular dynamics simulations of free Cdk2 and its complexes with inhibitors
(
Kriz Z.
,
Otyepka M.
,
Koca J.
), s. 500-501
artykuł:
Effect of inhibitors against the MAPK and PI3K pathways on head regeneration of hydra
(
Manuel G. C.
,
Aguilera A.
,
Salgado L. M.
), s. 502
artykuł:
Molecular features of selective polyphenolic inhibitors of protein kinase CK2
(
Meggio F.
,
Moro S.
,
Deana A. D.
,
Ben D. D.
,
Sarno S.
,
Zagotto G.
,
Pinna L. A.
), s. 503-505
artykuł:
Tumor-promoting phorbol esters bind directly to the regulatory domain of diacylglicerol kinase gamma
(
Shindo M.
,
Irie K.
,
Ohigashi H.
,
Kuriyama M.
,
Saito N.
), s. 507-508
artykuł:
Interaction of palmitoylcarnitine with protein kinase C in neurobalstoma NB-2a cells
(
Sobiesiak-Mirska J.
,
Nalecz M. J.
,
Nalecz K.
), s. 509
artykuł:
Phosphorylation of RAF-1 by kinase suppressor of RAS [KSR-1] is inhibited by 'MEK-specific' inhibitors PD 098059 and U0126 in differentiating HL60 cells
(
Wang X.
,
Studzinski G. P.
), s. 510
artykuł:
The kinetic mechanism of the phosphorylation of a model for a transcription factor substrate by ERK2
(
Waas W. F.
,
Dalby K. N.
), s. 511
artykuł:
Enzyme-linked immunosorbent assay for determination of P21-activated kinase activity
(
Yu J.-S.
,
Chang S.-H.
,
Chan W.-H.
,
Chen H.-C.
), s. 512
artykuł:
Structural and thermodynamic validation of inactive CDK2 as a template for structure-based drug design
(
Davies T. G.
,
Endicot J. A.
,
Noble M. E. M.
,
Johnson L. N.
,
Arris C. E.
,
Bentley J.
,
Boyle T.
,
Calvert A. H.
,
Curtin N. J.
,
Jewsbury P. J.
,
Gibson A. E.
,
Golding B. T.
,
Griffin R. J.
,
Hardcastle I.
,
Mesguiche V.
,
Parsons R.
,
Whitfield H.
,
Newell D. R.
), s. 514-515
artykuł:
Towards a PKB inhibitor
(
Klein S.
,
Geiger T.
,
Reuveni H.
,
Livnach N.
,
Levitzki A.
), s. 516
artykuł:
A new class of p38 map kinase inhibitors that exploit a novel binding site
(
Moss N.
,
Breitfelder S.
,
Cirillo P.
,
Gilmore T.
,
Graham A.
,
Hickey E.
,
Madwed J.
,
Moriak M.
,
Pargellis C.
,
Proto A.
,
Regan J.
,
Swinamer A.
,
Tong L.
,
Torcellini C.
), s. 517
artykuł:
Identification of the autoinhibitory domain of PKN: construction of a selective inhibitor of the PKN family
(
Mukai H.
,
Ono Y.
), s. 518
artykuł:
Molecular dynamics study on tree cdk2 and its complexes with purine-like inhibitors
(
Otyepka M.
,
Kriz Z.
,
Koca J.
), s. 519-521
artykuł:
Integrin-linked kinase 1 [ILK1]: a 'hot' therapeutic target
(
Costello P. C.
,
Kojic D. L.
,
Jabali M.
,
Zhang Z.
,
Azli L.
,
Yoganathan N.
,
Leung D.
,
Yan J.
,
Yee A.
,
Dadhar S.
,
Sanghera J.
), s. 522
artykuł:
A novel chemical genetic approach for V-SRC substrates reveals ordered assembly of retrograde signalling pathway
(
Shah K.
), s. 523
artykuł:
The discovery of 2-phentylamino-imidazo[4,5-h]Iso-quinolin-9-ones, a new class of inhibitors of Lck kinase with in vitro activity
(
Snow R. J.
,
Butz T.
,
Cardozo Z. G.
,
Eckner R. J.
,
Goldberg D. R.
,
Hammach A.
,
Jakes S.
,
Kapadia S.
,
Lukas S.
,
Morwick T. M.
,
Moss N.
,
Panzenbeck M.
,
Patel U. R.
,
Peet G. W.
,
Peterson J. D.
,
Prokopowicz III.A.S.
,
Takahashi H.
,
Tan J. D.
,
Tschantz M. A.
,
Wang X.-J.Zinter R.
), s. 524
artykuł:
BIBX 1382, a selective EGFR tyrosine kinase inhibitor, inhibits cell proliferation, induces cell differentation and displays anti-tumor activity against a variety of xenograft models
(
Solca F. F.
,
Adolf G.
,
Ahorn H.
,
Baum A.
,
Dohmann G.
,
Hilberg F.
,
Himmelsbach F.
,
Metz T.
,
van Meel J.
), s. 525-526
artykuł:
Synthesis and structure -activity relationships for soluble 6-substituted 4-anilinoquinoline-3-carbonitriles. Orally active, irreversible inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor [EGFR]
(
Tsou H.-R.
,
Overbeek E.
,
Reich M. F.
,
Floyd M. B.
,
Johnson B. D.
,
Gruber B. C.
,
Ye F.
,
Hallett W. A.
,
Nilakatan R.
,
Shen R.
,
Wang Y.-F.
,
Greenberger L. M.
,
Wissner A.
), s. 527
artykuł:
Protein ionization state prediction using a poisson-boltzmann method
(
Briggs J. M.
), s. 531-532
artykuł:
Prediction of rates of encounter of a small molecule with a protein using a Brownian dynamics method in a continuum solvent environment
(
Briggs J. M.
), s. 533-534
artykuł:
New leads for drug development from virtual screening
(
Klebe G.
), s. 535
artykuł:
Docking strategies: binding of substrate and inhibitors to S-adenoslyhomocysteine hydrolase - a case study
(
Kuczera K.
,
Hu Y.
,
Yin D.
,
Borchardt R. T.
), s. 536-537
artykuł:
Free energy simulations applied to biochemical problems
(
Kuczera K.
), s. 538-539
artykuł:
Simple model for ligand-macromolecule interactions
(
Rudnicki W. R.
,
Ginalski K.
), s. 540
artykuł:
Docking and scoring, exploring the limitations of understanding molecular recognition
(
Veith M.
), s. 541
artykuł:
Modelling drug-receptor interactions starting from the sequence of a receptor
(
Wong C. F.
), s. 542
artykuł:
Homology-derived three-dimensional strukture prediction of feruloyl esterase from Aspergillus niger
(
Aliwan F. O.
,
Pickersgill R.
,
Williamson G.
), s. 544
artykuł:
Dynamic pharmacophore model development and testing
(
Briggs J. M.
,
Barraca M. L.
,
Deng J.
,
Lee M.
,
Lee K. W.
,
Adesokan A.
), s. 545-546
artykuł:
Molecular dynamics studies and structural analyses of alanine racemase - as a drug design target
(
Briggs J. M.
,
Mustata G. I.
,
Huang H.-C.
,
Soares T. A.
), s. 547
artykuł:
Modelling the 3D structure of protein kinase C gamma and its interaction with specific inhibitor, chelerythrine
(
Brodacki P.
,
Ginalski K.
,
Lesyng B.
), s. 548
artykuł:
Quantum-mechanical calculations of the potential energy function for the phosphate transfer in model systems
(
Ginalski K.
,
Grochowski P.
,
Lesyng B.
), s. 549
artykuł:
Onkogenic activation caused by poitn mutations in the kinase domain of the met proto-oncogene: molecular modeling studies
(
Miller M.
,
Ginalski K.
,
Lesyng B.
,
Nakaigawa N.
,
Schmidt L.
,
Zbar B.
), s. 550
artykuł:
Molecular recognition in kinases through computational chemistry
(
Veith M.
), s. 551
artykuł:
Prediction of protonation states of phosphotyrosine in short peptides and proteins
(
Wojciechowski M.
,
Grycuk T.
,
Antosiewicz J.
,
Lesyng B.
), s. 552-553
artykuł:
Ser-Thr protein phosphatase-1 and -2A catalytic units: simulation of their interactions with selected substate and inhibitor sequences
(
Wozniak-Celmer E.
,
Oldziej S.
,
Ciarkowski J.
), s. 554-556
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