Association between body mass index and gastric cancer in Pomeranian men and women

• Autorzy: Adamowicz K.

Warianty tytułu

PL

Związek pomiędzy wskaźnikiem masy ciała i występowaniem gruczołowego raka żołądka wśród mężczyzn i kobiet w województwie pomorskim

• Języki publikacji: EN

Abstrakty

EN

Background. Within the last few decades, the prevalence of obesity has increased rapidly throughout the world. Epidemiological studies indicate a relationship of several types of cancer with obesity. The study aimed was to analyse the relation between body mass index (BMI) and the risk of developing gastric cancer. Material and methods. A multicenter case-control study was conducted between 2010 and 2015 in Poland. The study included 152 patients with gastric cancer and 152 patients with normal results of esophagogastroduodenoscopy performed in the same period and matched for age, education and sex. BMI was calculated by using patients’ height and weight. An analysis of environmental factors associated with the risk of gastric cancer was performed. Results. The group with the diagnosis of gastric cancer was characterised by significantly higher regular consumption of alcohol and was found to include a higher percentage of smokers compared to the control group. In a subgroup analysis, it was found that there was a significantly higher body mass index among both men and women diagnosed with gastric cancer. A relation between gastric cancer and both overweight (BMI 25.0-29.9 kg / m²) and obesity (BMI≥30 kg / m²) was established. In a multivariate analysis, this was an independent risk factor for gastric cancer. Conclusions. We suggest that BMI should be considered as an independent risk factor for developing gastric adenocarcinoma, which should lead to further research leading to the development of recommendations for the prevention of gastric cancer for people with high BMI.

PL

Wprowadzenie. W ciągu ostatnich kilku dekad występowanie nadwagi i otyłości wzrasta gwałtownie. Badania epidemiologiczne wskazują na związek kilku typów nowotworów złośliwych z nadwagą i otyłością. Celem naszej pracy była analiza relacji pomiędzy wskaźnikiem masy ciała (BMI) a ryzykiem zachorowania na gruczołowego raka żołądka. Materiał i metody. Wieloośrodkowe badanie kliniczno-kontrolne zostało przeprowadzone w latach 2010 do 2015 w województwie pomorskim w Polsce. Do badania włączono 152 pacjentów z rakiem żołądka i 152 pacjentów z prawidłowymi wynikami ezofagoduodendoskopii wykonywanymi w tym samym okresie. Przypadki zostały dopasowane pod względem wieku, wykształcenia i płci. BMI obliczano na podstawie wzrostu i wagi pacjenta. Dodatkowo przeprowadzono analizę czynników środowiskowych mogących mieć związek z ryzykiem zachorowania na gruczołowego raka żołądka. Wyniki. W grupie z rozpoznaniem raka żołądka stwierdzano wyraźnie wyższą częstość regularnego spożywania alkoholu i wyższy odsetek osób palących w porównaniu do grupy kontrolnej. W analizie podgrup stwierdzono znacznie podwyższony wskaźnik masy ciała zarówno wśród mężczyzn jak i kobiet, u których zdiagnozowano raka żołądka w stosunku do grupy kontrolnej. Relacja pomiędzy występowaniem raka żołądka i nadwagi (BMI 25.0-29.9 kg/ m²) lub otyłości (BMI≥30 kg / m²) była istotna statystycznie. W analizie wieloczynnikowej podwyższony BMI był niezależnym czynnikiem ryzyka rozwoju gruczołowego raka żołądka. Wnioski. Sugerujemy, że BMI należy traktować jako niezależny czynnik ryzyka rozwoju gruczolakoraka żołądka, co powinno prowadzić do dalszych badań prowadzących do opracowania zaleceń dotyczących zapobieganiu i wczesnemu wykrywaniu raka żołądka u osób z wysokim BMI.

Słowa kluczowe

EN

body mass index; man; woman; gastric cancer; human disease; public health; overweight; Pomeranian voivodship

• Wydawca: -
• Czasopismo: Health Problems of Civilization
• Rocznik: 2018
• Tom: 12
• Numer: 4
• Opis fizyczny: p.231-237,fig.,ref.

Twórcy

autor

Adamowicz K.

• F.Ceynova Specialist Hospital in Wejherowo, Wejherowo, Poland
• Provincial Center of Oncology in Gdansk Copernicus, Gdansk, Poland

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Identyfikatory

DOI

10.5114/hpc.2018.76517