Ultrasound vocalisation (USV) alterations in Purkinje cell specific TSC1 knockout mice

• Autorzy: Wiaderkiewicz J. , Barski J. J.
• Języki publikacji: EN

Abstrakty

EN

Tuberous sclerosis (TSC) is a genetic disorder, characterized by the emergence of multi-system benign tumors. Symptoms related to central nervous system disruptions include seizures, developmental delay and a varying range of behavioral disorders. Behavioral disorders can be identified by analyzing various parameters, many of which can be observed during social interactions where different types of communication come into play. One of the more universal methods of communication in mammals is vocalization, which in mice is realized both in the audible and ultrasonic range. We recorded and analyzed mouse vocalizations during a mousepup isolation test, where newborn mice emit the largest amount of USV’s. A range of sound parameters were analyzed including the rate of vocalization and numerous physical characteristics of sound, as well as single calls which were identified and classified.

• Wydawca: -
• Czasopismo: Acta Neurobiologiae Experimentalis
• Rocznik: 2013
• Tom: 73
• Numer: Suppl.1
• Opis fizyczny: p.51

Twórcy

autor

Wiaderkiewicz J.

• Center for Experimental Medicine, Medical University of Silesia, Katowice, Poland
• Department of Physiology, Medical University of Silesia, Katowice, Poland

autor

Barski J. J.

• Center for Experimental Medicine, Medical University of Silesia, Katowice, Poland
• Department of Physiology, Medical University of Silesia, Katowice, Poland