PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2018 | 74 | 03 |

Tytuł artykułu

Comparison of adiponectin levels and some metabolic parameters in dairy cows with subclinical and clinical ketosis

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The aim of the presented study was to evaluate the relationship between adiponectin and the non-esterified fatty acids (NEFA), β-hydroxybutyric acid (BHBA), glucose, albumin, gamma-glutamyl transferase (GGT), calcium, phosphorus and blood urea nitrogen (BUN) levels in healthy cows and cows suffering clinical or subclinical ketosis in the early postpartum period. A total of 45 Holstein-Friesian dairy cows, consisting of 15 with clinical ketosis, 15 with subclinical ketosis and 15 healthy controls, was used in the study. The selection of animals was based on blood BHBA levels and urine ketone strip results on day 7 after parturition. Blood adiponectin, NEFA, glucose, albumin, GGT, calcium, phosphorus and BUN were also measured on day 7 postpartum. Adiponectin levels were significantly lower in both clinical ketosis and subclinical ketosis groups compared to the control group. NEFA levels were higher and glucose and calcium levels were lower in both ketosis groups when compared to the control animals. On the other hand, blood albumin, GGT, phosphorus and BUN levels did not differ among study groups. Based on the results of the study, it can be stated that adiponectin may play a role in the pathogenesis of ketosis. This role could be a lower milk yield and better energy balance in early postpartum dairy cows with high adiponectin levels due to increased whole body tissue insulin sensitivity.

Wydawca

-

Rocznik

Tom

74

Numer

03

Opis fizyczny

p.182-186,ref.

Twórcy

autor
  • Deparment of Internal Medicine, Faculty of Veterinary Medicine, Siirt University, Siirt, Turkey
autor
  • Deparment of Internal Medicine, Faculty of Veterinary Medicine, Uludag University, Bursa, Turkey
  • Deparment of Biochemistry, Faculty of Veterinary Medicine, Uludag University, Bursa, Turkey
autor
  • Deparment of Internal Medicine, Faculty of Veterinary Medicine, Uludag University, Bursa, Turkey

Bibliografia

  • Banga A., Bodles A. M., Rasouli N., Ranganathan G., Kern P. A., Owens R. J.: Calcium IS Involved in Formation of High Molecular Weight Adiponectin. Metab. Syndr. Relat. D. 2008, 6, 103-111.
  • Cebra C. K., Garry F. B., Getzy D. M., Fettman M. J.: Hepatic Lipidosis in Anorectic, Lactating Holstein Cattle: A Retrospective Study of Serum Biochemical Abnormalities. J. Vet. Intern. Med. 1997, 11, 231-237.
  • Delfinia E., Petramalaa L., Caliumia C., Cotestaa D., Tomab G., Cavallarob G., Panzironib G., Diacintia D., Minisolaa S., D’Erasmoa E., Mazzuolia G. F., Letiziaa C.: Circulating leptin and adiponectin levels in patients with primary hyperparathyroidism. Metabolism 2007, 56, 30-36.
  • Drackley J. K.: Biology of dairy cows during the transition period: the final frontier? J. Dairy. Sci. 1999, 82, 2259-2273.
  • Duffield T.: Subclinical ketosis in lactating dairy cattle. Vet. Clin. N. Am. Food. A. 2000, 16, 231-253.
  • Eicher R., Liesegang A., Bouchard E., Tremblay A.: Influence of concentrate feeding frequency and intrinsic factors on diurnal variations of blood metabolites in dairy cows. Proc. Am. Assoc. Bov. Pract. Rome 1998, p. 198-202.
  • Grummer R. R.: Impact of changes in organic nutrient metabolism on feeding the transition dairy cow. J. Anim. Sci. 1995, 73, 2820-2833.
  • Hayirli A.: The Role of Exogenous Insulin in the Complex of Hepatic Lipidosis and Ketosis Associated with Insulin Resistance Phenomenon in Postpartum Dairy Cattle. Vet. Res. Commun. 2006, 30, 749-774.
  • Iwabu M., Yamauchi T., Okada-Iwabu M., Sato K., Nakagawa T., Funata M., Yamaguchi M., Namiki S., Nakayama R., Tabata M., Ogata H., Kubota N., Takamoto I., Hayashi Y. K., Yamauchi N., Waki H., Fukayama M., Nishino I., Tokuyama K., Ueki K., Oike Y., Ishii S., Hirose K., Shimizu T., Touhara K.: Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca²⁺ and AMPK/SIRT1. Nature 2010, 464, 1313-1319.
  • Jorritsma R., Balde E. S. J. C., Schukken Y. H., Wensing T. H., Wentink G. H.: Evaluation of a milk test for detection of subclincal ketosis. Vet. Quart. 1998, 20, 108-110.
  • Jorritsma R., Wensing T., Kruip T. A. M., Plam V., Noordhuizen J. P. T. M.: Metabolic changes in early lactation and impaired reproductive performance in dairy cows.Vet. Res. 2003, 34, 11-26.
  • Kabara E., Sordillo L. M., Holcombe S., Contreras G. A.: Adiponectin links adipose tissue function and monocyte inflamatory response during bovine metabolic stress. Comp. Immunol. Microb. 2013, 37, 49-58.
  • Konstantinos K.: The role of adiponectin in regulation of metabolism in dairy cows. PhD thesis, University of Nottingham 2012.
  • Leroy J. L. M. R., Vanholder T., Van Knegsel A. T. M., Garcia-Ispierto I., Bols P. E. J.: Nutrient Prioritization in dairy cows early postpartum: mismatch between metabolism and fertility? Reprod. Domest. Anim. 2008, 43, 96-103.
  • Mecitoglu Z., Senturk S., Akgul G., Udum D., Uzabaci E., Kasap S., Catik S.: Changes in circulating adiponectin and tumour necrosis factor-α and their relationship with insulin resistance in periparturient dairy cows. Vet. Res. 2016, 60, 163-167.
  • NRC.: Nutrient Requirements of Beef Cattle. Seventh Edition. National Academy Press, Washington, DC 2000.
  • Ohtani Y., Takahashi T., Sato K., Ardiyanti A., Song A. H., Sato R., Onda K., Wada Y., Obara Y., Suzuki K., Hagino A., Roh S. G., Katoh K.: Changes in circulating adiponectin and metabolic hormone concantration during periparturiant and lactation periods in holstein dariy cows. Anim. Sci. J. 2012, 83, 788-793.
  • Ospina P. A., Nydam D. V., Stokol T., Overton T. R.: Evelution of nonesterified fatty acids and beta-hydroxybutirate in transition dairy cattle in the northeastern United States: Critical thresholds for prediction of clinical diseases. J. Dairy. Sci. 2010, 93, 546-554.
  • Ropstad E., Halse K., Refsdal A. O.: Variations in parameters of liver function and plasma progesterone related to underfeeding and ketosis in a dairy herd. Acta. Vet. Scand. 1999, 30, 185-197.
  • Senturk S., Cihan H., Mecitoglu Z., Catik S., Akgul G. D., Kasap S., Topal O.: Prevalence of ketosis in dairy herds in Marmara, Aegean and Mediterranean regions of Turkey. Ankara. Unıv. Vet. Fak. Derg. 2016, 63, 283-288.
  • Sevinc M., Basoglu A., Oztok I., Sandikci M., Birdane F.: The clinical-chemical parameters, serum lipoproteins and fatty infiltration of the liver in ketotic cows. Turk. J. Vet. Anim. Sci. 1998, 22, 443-447.
  • Simenson E., Halse K., Gillund P., Lutnaes B.: Ketosis treatment and milk yield in dairy cows related to milk acetoacetate levels. Acta. Vet. Scand. 1990, 31, 433-440.
  • Singh S. P., Haussler S., Heinz J. F., Saremi B., Mielenz B., Rehage J., Danicke S., Mielenz M., Sauerwein H.: Supplementation with conjugated linoleic acids extends the adiponectin deficit during early lactation in dairy cows. Gen. Comp. Endocrinol. 2014, 198, 13-21.
  • Sun X., Michael B.: Zemel Calcium and 1,25-Dihydroxyvitamin D3 Regulation of Adipokine Expression. Obesity. 2007, 15, 340-348.
  • Strang B. D., Bertics S. J., Grummer R. R., Armentano L. E.: Effect of Long-Chain Fatty Acids on Triglyceride Accumulation, Gluconeogenesis, and Ureagenesis in Bovine Hepatocytes. J. Dairy. Sci. 1998, 81, 728-739.
  • Veenhuizen J. J., Drackley J. K., Richard M. J., Sanderson T. P., Miller L. D.: Young Metabolic Changes in Blood and Liver During Development and Early Treatment of Experimental Fatty Liver and Ketosis in Cows. J. Dairy. Sci. 1991, 74, 4238-4253.
  • Walsh R. B. J. S., Walton J. S., Kelton D. F., Leblanc S. J., Leslie K. E., Duffield T. F.: The effect of subclinical ketosis in early lactation on reproductive performance of postpartum dairy cows. J. Dairy. Sci. 2007, 90, 2788-2796.
  • Yamaguchi T., Kanazawa I., Takaoka S., Sugimoto T.: Serum calcium is positively correlated with fasting plasma glucose and insulin resistance, independent of parathyroid hormone, in male patients with type 2 diabetes mellitus. Metabolism 2011, 60, 1334-1339.
  • Yamauchi T., Kamon J., Minokoshi Y., Ito Y., Waki H., Uchida S., Yamashita S., Noda M., Kita S., Ueki K., Eto K., Akanuma Y., Froguel P., Foufelle F., Ferre P., Carling D., Kimura S., Nagai R., Kahn B. B., Kadowaki T.: Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nature. Med. 2002, 8, 1288-1295.
  • Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., Mori Y., Ide T., Murakami K., Tsuboyama-Kasaoka N., Ezaki O., Akanuma Y., Gavrilova O., Vinson C., Reitman M. L., Kagechika H., Shudo K., Yoda M., Nakano Y., Tobe K., Nagai R., Kimura S., Tomita M., Froguel P., Kadowaki T.: The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nature. Med. 2001, 7, 941-946.
  • Yameogo N., Oudraogo G. A., Kanyandek W. E. C., Sawadako G. J.: Relationship between ketosis and dairy cows’ blood metabolites in intensive production farms of the periurban area of Dakar. Trop. Anım. Health. Pro. 2008, 40, 483-490.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-f268f104-b1dd-4745-bf90-52122e6a0986
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.