PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2014 | 70 | 08 |

Tytuł artykułu

Diagnosis, tests and difficulties in canine and feline inflammatory bowel disease

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Canine and feline inflammatory bowel disease (IBD) is a group of idiopathic alimentary tract disorders diagnosed by the differential diagnosis method. Similarly to humans, the etiopathogenesis of IBD in small animals remains unknown. Blood tests, fecal examinations, intestinal permeability tests, medical imaging, and histopathological screening should be performed to eliminate other diseases and confirm IBD. The required tests prolong the time to diagnosis and increase costs. This article reviews numerous studies and findings relating to IBD in small animals during the diagnostic procedure. Unfortunately, despite a wide range of medical tests, no single diagnostic procedure can confirm the diagnosis. Thus, a clinical analysis should encompass the results of all tests, including the clinical exam, additional tests, histopathological screening, and responses to treatment. Novel biomarkers have been studied, but none of them is useful when applied alone. It seems that the key to finding a specific test or marker lies in the understanding of the etiopathogenesis of IBD.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

70

Numer

08

Opis fizyczny

p.460-467,ref.

Twórcy

autor
  • Department of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-719 Olsztyn, Poland
autor
  • Department of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-719 Olsztyn, Poland
autor
  • Department of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-719 Olsztyn, Poland
autor
  • Department of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-719 Olsztyn, Poland
autor
  • Department of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-719 Olsztyn, Poland
autor
  • Department of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-719 Olsztyn, Poland
autor
  • Department of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-719 Olsztyn, Poland

Bibliografia

  • 1. Allenspach K., Luchschander N., Styner M., Seibold F., Doherr M., Aeschbach D., Gaschen F.: Evaluation of assays for perinuclear antineutrophilic cytoplasmic antibodies and antibodies to Saccharomyces cerevisiae in dogs with inflammatory bowel disease. Am. J. Vet. Res. 2004, 65, 1279-1283.
  • 2. Allenspach K., Steiner J. M., Shah B. N., Berghoff N., Ruaux C., Williams D. A., Blum J. W., Gaschen F.: Evaluation of gastrointestinal permeability and mucosal absorptive capacity in dogs with chronic enteropathy. Am. J. Vet. Res. 2006, 67, 479-483.
  • 3. Allenspach K., Wieland B., Gröne A., Gaschen F.: Chronic enteropathies in dogs: Evaluation of risk factors for negative outcome. J. Vet. Intern. Med. 2007, 21, 700-708.
  • 4. Armstrong P. J., Williams D. A.: Pancreatitis in cats. Top. Companion Anim. Med. 2012, 27, 140-147.
  • 5. Baez J. L., Hendrick M. J., Walker L. M., Washabau R. J.: Radiographic, ultrasonographic and endoscopic findings in cats with inflammatory bowel disease of the stomach and small intestine: 33 cases (1990-1997). J. Am. Vet. Med. Assoc. 1999, 215, 349-354.
  • 6. Bailey S., Benigni L., Eastwood J., Garden O. A., McMahon L., Smith K., Steiner J. M., Suchodolski J. S., Allenspach K.: Comparisons between cats with normal and increased fPLI concentrations in cats diagnosed with inflammatory bowel disease. J. Small Anim. Pract. 2012, 51, 484-489.
  • 7. Barrs V., Beatty J.: Feline alimentary lymphoma: 1. Classification, risk factors, clinical signs and non-invasive diagnostics. J. Feline Med. Surg. 2012, 14, 182-190.
  • 8. Battersby I. A., Peters I. R., Day M. J., German A. J., Hall E. J.: Effect of intestinal inflammation on fecal elastase concentration in dogs. Vet. Clin. Path. 2005, 34, 49-51.
  • 9. Berghoff N., Steiner J. M.: Laboratory tests for the diagnosis and management of chronic canine and feline enteropathies. Vet. Clin. North Am. Small Anim. Pract. 2011, 41, 311-328.
  • 10. Cerón J. J., Eckersall P. D., Martinez-Subiela S.: Acute phase proteins in dogs and cats: current knowledge and future perspectives. Vet. Clin. Path. 2005, 34, 85-99.
  • 11. Citi S., Chimenti T., Marchetti V., Millanta F., Mannucci T.: Micronodular ultrasound lesions in the colonic submucosa of 42 dogs and 14 cats. Vet. Radiol. Ultrasound 2013, doi: 10.1111/vru.12077.
  • 12. Craven M., Simpson W., Ridyard A. E., Chandler M. L.: Canine inflammatory bowel disease: retrospective analysis of diagnosis and outcome in 80 cases (1995-2002). J. Small Anim. Pract. 2004, 45, 336-342.
  • 13. Delaney F., O’Brien R. T., Waller K.: Ultrasound evaluation of small bowel thickness compared to weight in normal dogs. Vet. Radiol. Ultrasoun. 2003, 5, 577-580.
  • 14. Dennis J. S., Kruger J. M., Mullaney T. P.: Lymphocytic/plasmacytic gastroenteritis in cats: 14 cases (1985-1990). J. Am. Vet. Med. Assoc. 1992, 200, 1712-1718.
  • 15. Frias R., Strube K., Ternes W., Collado M. C., Spillman T., Sankari S., Westermarck E.: Comparison of 51Chromium-labeled ethylenediamine tetraacetic acid and iohexol as blood markers for intestinal permeability testing in Beagle dogs. Vet. J. 2012, 192, 123-125.
  • 16. García-Sancho M., Rodríquez-Franco F., Sainz A., Rodríguez A., Silván G., Illera J. C.: Serum gastrin in canine chronic lymphocytic-plasmacytic enteritis. Can. Vet. J. 2005, 46, 630-634.
  • 17. Gaschen L.: Ultrasonography of small intestinal inflammatory and neoplastic diseases in dogs and cats. Vet. Clin. North Am. Small. Anim. Pract. 2011, 41, 329-344.
  • 18. Gaschen L., Kircher P.: Two-dimensional grayscale ultrasound and spectral Doppler waveform evaluation of dogs with chronic enteropathies. Clin. Tech. Small. Anim. Pract. 2007, 22, 122-127.
  • 19. German A. J., Hall E. J., Day M. J.: Chronic intestinal inflammation and intestinal disease in dogs. J. Vet. Intern. Med. 2003, 17, 8-20.
  • 20. German A. J., Hall E. J., Day M. J.: Relative deficiency in IgA production by duodenal explants from German Shepherd dogs with small intestinal disease. Vet. Immunol. Immunopathol. 2000, 76, 25-43.
  • 21. Gow A. G., Else R., Evans H., Berry J. L., Herrtage M. E., Mellanby R. J.: Hypovitaminosis D in dogs with inflammatory bowel disease and hypoalbuminaemia. J. Small. Anim. Pract. 2011, 52, 411-418.
  • 22. Guilford W. G., Center S. A., Strombeck D. R., Williams D. A., Meyer D. J.: Strombeck’s small animal gastroenterology. Saunders W. B. company, USA 1996, pp. 469.
  • 23. Gunawardana S. C., Jergens A. E., Ahrens F. A., Niyo Y.: Colonic nitrite and immunoglobulin G concentrations in dogs with inflammatory bowel disease. Am. Vet. Med. Assoc. 1997, 211, 318-321.
  • 24. Hall E. J., Rutgers H. C., Scholes S. F. E., Middleton D. J., Tennant B. J., King N. M., Kelly D. F.: Histiocytic ulcerative colitis in Boxer dogs in the UK. J. Small Anim. Pract. 1994, 35, 509-515.
  • 25. Heilmann R. M., Jergens A. E., Ackermann M. R., Barr J. W., Suchodolski J. S., Steiner J. M.: Serum calprotectin concentrations in dogs with idiopathic inflammatory bowel disease. Am. J. Vet. Res. 2012, 73, 1900-1907.
  • 26. Im Hof M., Schnyder M., Hartnack S., Stanke-Labesque F., Luckschander N., Burgener I. A.: Urinary leukotriene E4 concentrations as a potential marker of inflammation in dogs with inflammatory bowel disease. J. Vet. Intern. Med. 2012, 26, 269-274.
  • 27. Janeczko S., Atwater D., Bogel E., Greiter-Wilke A., Gerold A., Baumgart M., Bender H., McDonough P. L., McDonough S. P., Goldstein R. E., Simpson K. W.: The relationship of mucosal bacteria to duodenal histopathology, cytokine mRNA, and clinical disease activity in cats with inflammatory bowel disease. Vet. Microbiol. 2008, 128, 178-193.
  • 28. Jergens A. E.: Feline idiopathic inflammatory bowel disease: what we know and what remains to be unraveled. J. Feline Med. Surg. 2012, 14, 445-458.
  • 29. Jergens A. E., Crandell J. M., Evans R., Ackermann M., Miles K. G., Wang C.: A clinical index for disease activity in cats with chronic enteropathy. J. Vet. Intern. Med. 2010, 24, 1027-1033.
  • 30. Jergens A. E., Moore F. M., Haynes J. S., Miles K. G.: Idiopathic inflammatory bowel disease in dogs and cats. 84 cases (1987-1990). J. Am. Vet. Med. Assoc. 1992, 201, 1603-1612.
  • 31. Jergens A. E., Schreiner C. A., Frank D. E.: A scoring index for disease activity in canine inflammatory bowel disease. J. Vet. Intern. Med. 2003, 17, 291-297.
  • 32. Johnston K. L., Ballèvre O. P., Batt R. M.: Use of an orally administered combined sugar solution to evaluate intestinal absorption and permeability in cats. Am. J. Vet. Res. 2001, 62, 111-118.
  • 33. Joossens S., Reinisch W., Vermeire S., Sendid B., Poulain D., Peeters M., Geboes K., Bossuyt X., Vandewalle P., Oberhuber G., Vogelsang H., Rutgeerts P., Colombel J. F.: The value of serologic markers in indeterminate colitis: a prospective follow-up study. Gastroenterology 2002, 122, 1242-1247.
  • 34. Kathrani A., House A., Catchpole B., Murphy A., German A., Werling D., Allenspach K.: Polymorphism in the Tlr4 and Tlr5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs. PLoS One 2010, 5: e15740.
  • 35. Kiupel M., Smedley R. C., Pfent C., Xie Y., Xue Y., Wise A. G., DeVaul J. M., Maes R. K.: Diagnostic Algorithm to Differentiate Lymphoma From Inflammation in Feline Small Intestinal Biopsy Samples. Vet. Pathol. 2011, 48, 212-222.
  • 36. Kobayashi S., Ohno K., Uetsuka K., Nakashima K., Setoguchi A., Fujino Y., Tsujimoto H.: Measurement of intestinal mucosal permeability in dogs with lymphocytic-plasmacytic enteritis. J. Vet. Med. Sci. 2007, 69, 745-749.
  • 37. Lecoindre P.: Chronic inflammatory bowel diseases, etiopathogeny, diagnosis. Bull. Acad. Vét. France 2006, 159, 333-342.
  • 38. Luckschander N., Allenspach K., Hall J., Seibold F., Gröne A., Doherr M. G., Gaschen F.: Perinuclear antineutrophilic cytoplasmic antibody and response to treatment in diarrheic dogs with food responsive disease or inflammatory bowel disease. J. Vet. Intern. Med. 2006, 20, 221-227.
  • 39. Maeda S., Ohno K., Uchida K., Nakashima K., Fukushima K., Tsukamoto A., Nakajima M., Fujino Y., Tsujimoto H.: Decresed immunoglobulin A concentrations in feces, duodenum, and peripheral blood mononuclear cells of dogs with inflammatory bowel disease. J. Vet. Intern. Med. 2013, 27, 47-55.
  • 40. Manolakis A. C., Kapsoritakis A. N., Georqoulias P., Tzavara C., Valotassiou V., Kapsoritaki A., Potamianos S. P.: Moderate performance of serum S100A12, in distinguishing inflammatory bowel disease from irritable bowel syndrome. BMC Gastroenterol. 2010, 10, 188.
  • 41. McCann T. M., Ridyard A. E., Else R. W., Simpson J. W.: Evaluation of disease activity markers in dogs with idiopathic inflammatory bowel disease. J. Small Anim. Pract. 2007, 48, 620-625.
  • 42. Melgarajo T., Williams D. W., Asem E. K.: Enzyme-linked immunosorbent assay for canine α1-protease inhibitor. Am. J. Vet. Res. 1998, 59, 127-130.
  • 43. Naganuma M., Hosoe N., Ogata H.: Inflammatory bowel disease and novel endoscopic technologies. Dig. Endosc. 2013, 26, doi: 10.1111/den.12161.
  • 44. Neumann H., Neurath M. F., Mudter J.: New endoscopic approaches in IBD. World J. Gastroenterol. 2011, 17, 63-68.
  • 45. Newell S. M., Graham J. P., Roberts G. R., Ginn P. E., Harrison J. M.: Sonography of the normal feline gastrointestinal tract. Vet. Radiol. Ultrasound 1999, 40, 40-43.
  • 46. Penninck D., Smyers B., Webster C. R. L., Rand W., Moore A. S.: Diagnostic value of ultrasonography in differentiating enteritis from intestinal neoplasia in dogs. Vet. Radiol. Ultrasound 2003, 44, 570-575.
  • 47. Randell S. C., Hill R. C., Scott K. C., Omori M., Burrows C. F.: Intestinal permeability testing using lactulose and rhamnose: a comparison between clinically normal cats and dogs and between dogs of different breeds. Res. Vet. Sci. 2001, 71, 45-49.
  • 48. Ridgway J., Jergens A. E., Niyo Y.: Possible causal association of idiopathic inflammatory bowel disease with thrombocytopenia in the dog. J. Am. Hosp. Assoc. 2001, 37, 65-74.
  • 49. Rudorf H., van Shaik G., O’Brien R. T., Brown P. J., Barr F. J., Hall E. J.: Ultrasonographic evaluation of the small intestinal wall in dogs with inflammatory bowel disease. J. Small Anim. Pract. 2005, 46, 322-326.
  • 50. Rutgers H. C., Batt R. M., Proud F. J.: Intestinal permeability and function in dogs with small intestinal bacterial overgrowth. J. Small. Anim. Pract. 1996, 37, 428-434.
  • 51. Rychlik A., Nieradka R., Kander M., Depta A., Nowicki M., Sarti K.: Usefulness of endoscopic examination for the diagnosis of inflammatory bowel disease in the dog. A case report. Pol. J. Vet. Sci. 2007, 10, 113-118.
  • 52. Rychlik A., Nieradka R., Kander M., Nowicki M., Wdowiak M., Kołodziejska-Sawerska A.: A correlation between the Canine Inflammatory Bowel Disease Activity Index score and the histopathological evaluation of the small intestinal mucosa in canine inflammatory bowel disease. Pol. J. Vet. Sci. 2012, 15, 315-321.
  • 53. Scott K. D., Zoran D. L., Mansell J., Norby B., Willard M. D.: Utility of endoscopic biopsies of the duodenum and ileum for diagnosis of inflammatory bowel disease and small cell lymphoma in cats. J. Vet. Intern. Med. 2011, 25, 1253-1257.
  • 54. Simpson K. W., Fyfe J., Cornetta A., Sachs A., Strauss-Ayali D., Lamb S. V., Reimers T. J.: Subnormal Concentrations of Serum Cobalamin (Vitamin B12) in Cats with Gastrointestinal Disease. J. Vet. Intern. Med. 2001, 15, 26-32.
  • 55. Sørensen S. H., Proud F. J., Rutgers H. C.: A blood test for intestinal permeability and function: a new tool for the diagnosis of chronic intestinal disease. Clin. Chim. Acta. 1997, 262, 103-115.
  • 56. Swanson C. M., Smedley R. C., Saavedra P. V., Kiupel M., Kitchell B. E.: Expression of the Bcl-2 apoptotic marker in cats diagnosed with inflammatory bowel disease and gastrointestinal lymphoma. J. Feline Med. Surg. 2012, 14, 741-745.
  • 57. Tamboli C. P., Neut C., Desreumaux P., Colombel J. F.: Dysbiosis in inflammatory bowel disease. Gut 2004, 53, 1-4.
  • 58. Vieira A., Fang C. B., Rolim E. G., Klug W. A., Steinwurz F., Rossini L. G., Candelária P. A.: Inflammatory bowel disease activity assessed by fecal calprotectin and lactoferrin: correlation with laboratory parameters, clinical, endoscopic and histopathological indexes. BMC Res Notes. 2009, 2, 221.
  • 59. Weiss D. J., Gagne J. M., Armstrong P. J.: Relationship between inflammatory hepatic disease and inflammatory bowel disease, pancreatitis and nephritis in cats. J. Am. Vet. Med. Assoc. 1996, 209, 1114-1116.
  • 60. Willard M. D., Jergens A. E., Duncan R. B., Leis M. S., McCracken M. D., DeNovo R. C., Heilmann R. C., Slater M. R., Harbison J. L.: Intraobserver variation among histopathologist evaluation of intestinal tissue from dogs and cats. J. Am. Vet. Med. Assoc. 2002, 220, 1172-1182.
  • 61. Willard M. D., Lovering S. L., Cohen N. D.: Quality of tissue specimens obtained endoscopically from duodenum of dogs and cats. J. Am. Vet. Med. Assoc. 2001, 219, 474-479.
  • 62. Willard M. D., Moore G. E., Denton B. D., Day M. J., Mansell J., Bilzer T., Wilcock B., Gualtieri M., Olivero D., Lecoindre P., Twedt D. C., Collett M. G., Hall E. J., Jergens A. E., Simpson J. W., Else R. W., Washabau R. J.: Effect of tissue processing on assessment of endoscopic intestinal biopsies in dogs and cats. J. Vet. Intern. Med. 2012, 24, 84-88.
  • 63. Winterkamp S., Weidenhiller M., Otte P., Stolper J., Schwab D., Hahn E. G., Raithel M.: Urinary excretion of N-methylhistamine as a marker of disease activity in inflammatory bowel disease. Am. J. Gastroenterol. 2002, 97, 3071-3077.
  • 64. Yamagami H., Watanabe K., Kamata N., Sogawa M., Arakawa T.: Small bowel endoscopy in inflammatory bowel disease. Clin. Endosc. 2013, 46, 321-326.
  • 65. Zwingenberger A. L., Marks S. L., Baker T. W., Moore P. F.: Ultrasonographic evaluation of the muscularis propria in cats with diffuse small intestinal lymphoma or inflammatory bowel disease. J. Vet. Intern. Med. 2010, 24, 289-292.

Uwagi

Rekord w opracowaniu

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-f20d8deb-6cb6-4df8-8037-1c19c63556a7
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.