Effect of in owo injection of aroclor 1254 on embryonic development, time of hatching and blood thyroid hormone levels in one-day-old chicken

• Autorzy: Lis M.W. , Glodek, K. , Sechman, A. , Wator, D. , Pawlak, K. , Niedziolka, J. W.
• Języki publikacji: EN

Abstrakty

EN

The effect of Aroclor 1254 (mixture of several polychlorinated biphenyls, PCBs) on chicken embryogenesis and hatching process was investigated. Aroclor 1254 was injected in ovo at the 4th d of embryogenesis at doses of 0 (control), 10, 100, 1,000 ng/egg (n=120 eggs/group). The incubation was carried out under standard conditions. Course of hatching was recorded for each group. Blood samples were collected from ten one-day-old chickens, which were randomly chosen from each group. Following blood sampling, the chicks were decapitated, and their livers and hearts were weighed. Thyroxine (T₄) and triiodothyronine (T₃) concentrations in blood plasma were determined by RIA method. In ovo injection of Aroclor 1254 did not affect the final rate of hatching. There was no influence of the PCB mixture on body weight and weight of the liver and heart. The compound injected at doses of 10 and 100 ng/egg did not affect T₄ concentrations; however, the highest dose of the PCB mixture decreased its level by 37% (P≤0.05). Aroclor 1254 at a dose of 10 ng/egg decreased by 20% T₃ concentration while at a dose of 1,000 ng/egg elevated the concentration of this hormone by 17% (P≤0.05). The data presented suggest that injection of PCBs mixture in ovo at the early stages of embryogenesis affects embryonic development and influences thyroid hormone concentration in blood plasma in one-day-old chickens.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2011
• Tom: 55
• Numer: 2
• Opis fizyczny: p.293-298, fig.,ref.

Twórcy

autor

Lis M.W.

• Department of Animal Physiology and Endocrinology, University of Agriculture in Krakow, 30-059 Krakow, Poland

autor

Glodek, K.

autor

Sechman, A.

autor

Wator, D.

autor

Pawlak, K.

autor

Niedziolka, J. W.

Bibliografia

• 1. Beck V., Roelens S.A, Maervoet J., Schepens P., Darras V.M.: Interaction of PCBs with thyroid hormone levels and time of hatching in chicken embryos. Ann NY Acad Sci 2005, 1040, 224-226.
• 2. Beck V., Roelens S.A., Darras V.M.: Exposure to PCB 77 induces tissue-dependent changes in iodothyronine deiodinase activity patterns in the embryonic chicken. Gen Comp Endocrinol 2006, 148, 327-335.
• 3. Blankenship A., Hilscherova K., Nie M., Coady K., Villalobos S., Coady K., Villalobos S., Kannan K., Powell D., Bursian S., Giesy J.: Mechanisms of TCDD- induced abnormalities and embryo lethality in white leghorn chickens. Comp Biochem Physiol C Toxicol Pharmacol 2003, 136, 47-62.
• 4. Brouwer A., Longnecker M., Birnbaum L., Cogliano J., Kostyniak P., Moore J., Schantz S., Winneke G.: Characterization of potential endocrine-related health effects at low-dose levels of exposure to PCBs. Environ Health Perspect 1999, 107, Suppl 4, 639-649.
• 5. Brouwer A., Morse D.C., Lans M.C., Schuu A.G., Murk A.J., Klasson-Wehler E., Bergman A., Visser T.J.: Interactions of persistent environmental organohalogens with the thyroid hormone system: mechanisms and possible consequence for animal and human health. Toxicol Ind Health 1998, 14, 59-84.
• 6. Bruggeman V., Swennen Q., De Ketelaere B., Onagbesan O., Tona K., Decuypere E.: Embryonic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in chickens: effects of dose and embryonic stage on hatchability and growth. Comp Biochem C Toxicol Pharmacol 2003, 136, 17-28.
• 7. Crofton K.M., Elena S., Craft E.S., Hedge J.M., Gennings C., Simmons J.E., Carchman R.A., Carter Jr W.H., DeVito M.J.: Thyroid-hormone-disrupting chemicals: evidence for dose-dependent additivity or synergism. Environ Health Perspect 2005, 113, 1549- 1554.
• 8. Darras V.M., Visser T.J., Berghman L.R., Kühn E.R.: Ontogeny of type I and type III deiodinase activities in embryonic and posthatch chicks: relationship with changes in plasma triiodothyronine and growth hormone. Comp Biochem Physiol 1992, 103A, 131-136.
• 9. Darras V.M., Van Herck S.L.J., Geysens S., Reyns G.E.: Involvement of thyroid hormones in chicken embryonic brain development. Gen Comp Endocrinol 2009, 163, 58-62.
• 10. Decuypere E., Kuhn E.: Thyroid hormone physiology in Galliformes: Age and stain related changes in physiological control. Am Zoolog 1988, 28, 401 -415.
• 11. Gould J., Cooper K., Scanes C.: Effects of polychlorinated biphenyl mixtures and three specific congeners on growth and circulating growth-related hormones. Gen Comp Endocrinol 1997, 106, 221-230.
• 12. Gould J., Cooper K., Scanes C.: Effects of polychlorinated biphenyls on thyroid hormones and liver type I monodeiodinase in the chick embryo. Ecotoxicol Environ Saf 1999, 43, 195-203.
• 13. Gregoraszczuk E.L., Ptak A., Karniewska M., Ropstadb E.: Action of defined mixtures of PCBs, p,p'-DDT and its metabolite p,p'-DDE, on co-culture of porcine theca and granulosa cells: Steroid secretion, cell proliferation and apoptosis. Reprod Toxicol 2008, 26, 170-174.
• 14. Kania-Korwel I., Hornbuckle K.C., Peck A., Ludewig G., Robertson L.W., Sulkowski W.W., Espandiari P., Gairola C.G., Lehmler H.J.: Congener-specific tissue distribution of Aroclor 1254 and a highly chlorinated environmental PCB mixture in rats. Environ. Sci Technol 2005, 39, 3513-3520.
• 15. Kirkegaard M., Sonne C., Dietz R., Letcher R.J., Jensen A.L., Hansen S.S., Jenssen B.M., Grandjean P.: Alterations in thyroid hormone status in Greenland sledge dogs exposed to whale blubber contaminated with organohalogen compounds. Ecotoxicol Environ Saf 2011, 74, 157-163.
• 16. Lis. M.W., Sechman A., Niedziółka J.W., Rząsa J.: Effect of paracetamol injection in ovo on course of hatching and thyroid hormone levels in chicken embryo. Bull Vet Inst Pulawy 2006, 50, 537-542.
• 17. Powell D., Aulerich R., Meadows J., Tillitt D., Giesy J., Stromberg K., Bursian S.: Effects of 3,3',4,4',5- pentachlorobiphenyl (PCB126) and 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) injected into the yolk of chicken (Gallus domesticus) eggs prior to incubation. Arch Environ Contam Toxicol 1996, 31, 404- 409.
• 18. Roelens S.A., Beck V., Maervoet J., Aerts G., Reyns G.E., Schepens P., Darras V.M.: The dioxin-like PCB 77 but not the ortho-substituted PCB 153 interferes with chicken embryo thyroid hormone homeostasis and delays hatching. Gen Comp Endocrinol 2005, 143, 1-9.
• 19. Romanoff A.L., Romanoff A.J.: Spontagenous malformations. In: Pathogenesis of the avian embryo. Wiley-Interscience. New York - London - Sydney - Toronto, 1972, pp. 15-34.
• 20. Rushneck D., Beliveau A., Fowler B., Hamilton C., Hoover D., Kaye K., Berg M., Smith T., Telliard W., Roman H., Ruder E., Ryan L.: Concentrations of dioxin- like PCB congeners in unweathered Aroclors by HRGC/HRMS using EPA method 1668A. Chemosphere 2004, 54, 79-87.
• 21. Salay E., Garabrant D.: Polychlorinated biphenyls and thyroid hormones in adults: A systematic review appraisal of epidemiological studies. Chemosphere 2009, 74, 1413-1419.
• 22. Sechman A., Lis M.W., Hrabia A., Niedziółka J.W., Rząsa J.: Dioxin (TCDD) injected in ovo changes thyroid hormones level in blood of one-day-old chicks. Abstracts of XXXV ESNA Annual Meeting Amiens, France, 2005, p. 24.
• 23. Sechman A., Niedziółka J., Lis M., Rząsa J.: Changes in thyroid hormone levels in chicken embryo exposed to extremely low frequency electromagnetic field. Arch Geflugelk 2006, 70, 41-47.
• 24. Sechman A., Rząsa J., Paczoska-Eliasiewicz H.: Effect of non-steroidal aromatase inhibitor on blood plasma ovarian steroid and thyroid hormones in laying hen (Gallus domesticus). J Vet Med A 2003, 50, 333-338.
• 25. Shiraishi F., Okumura M., Nomachi T., Serizawa S., Nishikawa J., Edmonds J.S., Shiraishi H., Morita M.: Estrogenic and thyroid hormone activity of a series of hydroxy-polychlorinated biphenyls. Chemosphere 2003, 52, 33-42.
• 26. Summer C., Giesy J., Bursian S., Render J., Kubiak T., Jones P., Verbrugge D., Aulerich R.: Effects induced by feeding organochlorine-contaminated carp from Saginaw Bay, Lake Huron, to laying White Leghorn hens. II. Embryotoxic and teratogenic effects. J Toxicol Environ Health 1996, 49, 409-438.
• 27. Van den Berg M., Birnbaum L., Bosveld A., Brunström B., Cook P., Feeley M., Giesy J., Hanberg A., Hasegawa R., Kennedy S., Kubiak T., Larsen J., Van Leeuwen F., Liem A., Nolt C., Peterson R., Poellinger L., Safe S., Schrenk D., Tillitt D., Tysklind M., Younes M„ Waern F., Zacharewski T.: Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ Health Perspect 1998, 106, 775-792.
• 28. Van der Geyten S., Sanders J.P., Kaptein E., Darras V.M., Kühn E.R., Leonard J.L., Visser T.J.: Expression of chicken hepatic type I and type III iodothyronine deiodinases during embryonic development. Endocrinology 1997, 13, 5144-5152.
• 29. Van Der Geyten S., Van Der Rynde I., Segers I.B., Kuhn E.R., Darras V.M.: Differential expression of iodothyronine deiodinases in chicken tissues during the last week of embryonic development. Gen Comp Endocrinol 2002, 128, 65-73.
• 30. Yang J.M., Salmon A.G., Marty M.A.: Development of TEFs for PCB congeners by using an alternative biomarker -Thyroid hormone levels. Regulat Toxicol Pharmacol 2010, 56, 225-236.
• 31. Zoeller R.T.: Environmental chemicals targeting thyroid. Hormones 2010, 9, 28-40.

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