Stress - induced changes of interleukin - 1beta within the limbic system in the rat

• Autorzy: Badowska-Szalewska E. , Klejbor I. , Sidor-Kaczmarek J. , Cecot T. , Lietzau G. , Spodnik J. H. , Morys J.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to investigate the influence of two periods of life, namely P28 and P360, on the changes in interleukin-1beta (IL-1β) immunoreactivity (-ir) in the hippocampus (CA1, CA3, DG) and amygdala (central-CeA, medial-MeA) caused by acute and repeated open field (OF), or by forced swim (FS) exposition. Rats were divided into groups: non-stressed, exposed to acute (one-time for 15 min) and chronic stressors (21 days for 15 min daily). We found IL-1β-ir in the control group to be higher in P360 than in P28. In P28, under OF and FS exposure, IL-1β-ir in the CeA remained unaltered but increased in the MeA and in the hippocampus after acute and chronic stress. In P360 no changes were observed in the IL-1β-ir level after acute and chronic stimulation. These data demonstrate that only the levels of IL-1β-ir in juvenile rat brains are affected by FS and OF. Additionally, there was no significant difference between FS and OF stimulation in IL-1β-ir. (Folia Morphol 2009; 68, 3: 119–128)

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2009
• Tom: 68
• Numer: 3
• Opis fizyczny: p.119-128,fig.,ref.

Twórcy

autor

Badowska-Szalewska E.

• Department of Anatomy and Neurobiology, Medical University of Gdansk, Debinki 1, 80–211 Gdansk, Poland

autor

Klejbor I.

• Department of Anatomy and Neurobiology, Medical University of Gdansk, Debinki 1, 80–211 Gdansk, Poland

autor

Sidor-Kaczmarek J.

• Department of Anatomy and Neurobiology, Medical University of Gdansk, Debinki 1, 80–211 Gdansk, Poland

autor

Cecot T.

• Department of Anatomy and Neurobiology, Medical University of Gdansk, Debinki 1, 80–211 Gdansk, Poland

autor

Lietzau G.

• Department of Anatomy and Neurobiology, Medical University of Gdansk, Debinki 1, 80–211 Gdansk, Poland

autor

Spodnik J. H.

• Department of Anatomy and Neurobiology, Medical University of Gdansk, Debinki 1, 80–211 Gdansk, Poland

autor

Morys J.

• Department of Anatomy and Neurobiology, Medical University of Gdansk, Debinki 1, 80–211 Gdansk, Poland

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