Wewnątrzkomórkowa ekspresja wybranych białek wiążących wapń w neuronach hipokampa u szynszyli

• Autorzy: Szalak R. , Jaworska-Adamu J.

Warianty tytułu

EN

Intracellular expression of selected calcium-binding proteins in the neurons of a chinchilla’s hippocampus

• Języki publikacji: PL

Abstrakty

EN

The main aim of the study was to investigate the intracellular localization of the following calcium-binding proteins: parvalbumin, calbindin and calretinin. 15 sexually mature chinchilla males (about 1.5 years old) were used in the examination. The hippocampus was collected from each immediately after the slaughter, fixed and properly prepared for immunohistochemical examinations. Peroxidase-anti-peroxidase (PAP) reaction was carried out using specific antibodies against parvalbumin and calbindin D28k, as well as calretinin. Our own examination results have shown cytoplasmic as well as nuclear reactions in the examined regions of the hippocampal areas (CA1-CA4) and dentate gyrus. Only in the CA2 area was no nuclear reaction observed for the examined proteins, as well as in the CA1 area for calretinin. Intracellular localization of calcium-binding proteins proves that regulatory functions of parvalbumin, calbindin and calretinin lead to neuronal plasticity, i.e. to a change of their activity. Therefore, calcium-binding proteins may be indirectly involved in the regulation of metabolic processes affecting basic vital functions of neurons.

Słowa kluczowe

PL

szynszyle; hipokamp; neurony; bialka wiazace wapn; parwalbumina; kalbindyna D28K; kalretynina; ekspresja bialek

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2011
• Tom: 67
• Numer: 10
• Opis fizyczny: s.695-699,fot.,tab.,bibliogr.

Twórcy

autor

Szalak R.

• Katedra Anatomii i Histologii Zwierząt, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy w Lublinie, ul.Akademicka 12, 20-033 Lublin

autor

Jaworska-Adamu J.

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