Importance for experiments in human medicine of imaging modalities for macroanatomical and histological study of rabbit suprarenal glands

• Autorzy: Dilek O.G. , Dimitrov R.S. , Stamatova-Yovcheva K.D. , Yovchen D.G. , Mihaylov R.
• Języki publikacji: EN

Abstrakty

EN

The morphological characteristics of the rabbit adrenal glands are currently investigated using routine imaging modalities. The aim of the study was to collect and interpret major findings and information in the literature on the rabbit as an animal model for investigations in humans. The suprarenal glands of thirty-four mature, clinically healthy New Zealand rabbits were studied using anatomical, routine histology, radiology, computed tomography, ultrasonography, and magnetic resonance imaging methods. The results demonstrated that the rabbit suprarenal glands are paired ellipsoid organs. The right gland was close to the right kidney, whereas the left gland was located at a distance from the left kidney. The capsule was composed of dense connective tissue. The parenchyma consisted of three zones: zona glomerulosa, zona fasciculate, and zona reticularis. The medulla was in the center of the glandular parenchyma. The glands’ radiological and CT features defined their position relative to the right and left kidneys. The right suprarenal gland was with normal attenuation. The left suprarenal gland was located at a distance from the left kidney. The US features of the glands demonstrated variability in darkness and contrast, revealing specific histological features. The MRI peculiarities of the glands defined them as well visible findings.

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2019
• Tom: 75
• Numer: 11
• Opis fizyczny: p.684-692,fig.,ref.

Twórcy

autor

Dilek O.G.

• Department of Anatomy, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University, Burdur, Turkey

autor

Dimitrov R.S.

• Department of Veterinary Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria

autor

Stamatova-Yovcheva K.D.

• Department of Veterinary Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria

autor

Yovchen D.G.

• Department of Veterinary Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria

autor

Mihaylov R.

• Department of Animal Morphology, Physiology and Nutrition, Faculty of Agriculture, Trakia University, 6000 Stara Zagora, Bulgaria

Bibliografia

• Abidu-Figueiredo M., Xavier-Silva B., Cardinot T., Babinski M., Chagas A.: Celiac artery in New Zealand rabbit: anatomical study of its origin and arrangement for experimental research and surgical practice. Pesqui. Vet. Bras. 2008, 28, 237-240.
• Ahmadpanahi J.: Anatomical and Histological Studies of Accessory Adrenal Nodules in Caspian Miniature Horses. Turk. J. Vet. Anim. Sci. 2007, 31, 275-278.
• Banzato T., Bellini L., Contiero B., Selleri P., Zotti A.: Abdominal ultrasound features and reference values in 21 healthy rabbits. Vet. Rec. 2015, 176, 101. doi: 10.1136/vr.102657.
• Barone R., Simoens P.: Glandes surrénales, [in:] Anatomie Comparée des Mammifères Domestiques, tome 7: neurologie, II: système nerveux périphérique; glandes endocrines; esthésiologie. Edition Vigot, Paris 2010.
• Besso J. G., Tidwell A. S., Gliatto J. M.: Retrospective review of the ultrasonographic features of adrenal lesions in 21 ferrets. Vet. Radiol. Ultrasound 2005, 41, 345-352.
• Dimitrov R.: Morphofunctional and imaging features of the male accessories glands and pelvic part of the urethra in the tomcat. PhD Thesis, Trakia University, Stara Zagora, Bulgaria 2009.
• Dimitrov R., Chaprazov T.: An anatomic and contrast enhanced radiographic investigation of the rabbit kidneys, ureters and urinary bladder. Rev. Med. Vet. 2012, 163, 469-474.
• Dimitrov R., Kostov D., Stamatova K., Yordanova V.: Anatomotopographical and morphological analysis of normal kidneys of rabbit (Oryctolagus cuniculus). Trakia J. Sci. 2012, 10, 79-84.
• Dimitrov R. S.: Ultrasound features of kidneys in the rabbit (Oryctolagus cuniculus). Vet. World 2012, 5, 274-278.
• Dimova T.: Histological features of goat adrenal gland during puberty. C. R. Acad. Bulg. Sci. 2003, 56, 91-96.
• Dorotea S. B., Banzato T., Bellini L., Contiero B., Zotti A.: Radiographic anatomy of dwarf rabbit abdomen with normal measurements. BJVM 2016, 19, 96-107.
• Eken E., Çorumluoglu Ö., Paksoy Y., Beşoluk K., Kalaycı İ.: A study on evaluation of 3D virtual rabbit kidney models by multidetector computed tomography images. Anatomy 2009, 3, 40-44, doi:10.2399/ana.09.009.
• Harrison R. G.: A comparative study of the vascularization of the adrenal gland in the rabbit, rat and cat. J. Anat. 1951, 85, 12-23.
• Henninger W., Frame M., William M.: CT features of alveolotis and sinusitis in horses. Vet. Radiol. Ultrasound 2003, 44, 269-276.
• Hussein A. A., Abass T. A.: Comparative anatomical and histological study of the rabbit (Oryctolagus cuniculus). DASJ 2015, 7, (2), 1-11.
• Hynynen K., Damianou C., Colucci V., Unger E.: MR monitoring of focused ultrasonic surgery of renal cortex: experimental and simulation studies. J. Magn. Reson. Imaging 2005, 5, 259-266.
• Karakurum E., Özgel Ö., Dursun N.: Morphology and Arterial Vasculature of Donkey (Equus asinus L.) Adrenal Gland. Turk. J. Vet. Anim. Sci. 2008, 32, 469-473.
• Kastler B., Vetter D., Patay Z., Germain P. eds.: Comprendre l’IRM: manuel d’auto-apprentissage, 4th ed. Paris: Masson Bulgarian translation by Prof. Vassil Hadjidekov, Physical Principles of MRI. Medi. Phys. Education Sofia 2005, p. 23.
• Krause W., Schönborn A., Rupp K.: CT imaging with iopromide liposomes in a rabbit model. J. Liposome Res. 2011, 21, 229-236.
• Kressl M., Becker K., Schloegl S., Schlotter H., Kaiser F., Reiners C., Lassmann M.: Multimodal small animal imaging: Combination of 3D-ultrasound and small animal Pet/Spect. J. Nucl. Med. 2009, 50, 295.
• Lauridsen H., Hansen K., Wang T., Agger P., Andersen J., Knudsen P., Rasmussen A., Uhrenholt L., Pedersen M.: Inside out: Modern Imaging Techniques to Reveal Animal Anatomy. Plos One 2011, 6, (3), e17879, doi: 10.1371/journal.pone.0017879.
• Leander P., Mansson S., Ege T., Besjakov J.: CT and MR imaging of the liver using liver-specific contrast media. A comparative study in a tumour model. Acta Radiol. 1996, 37, 242-249.
• Lenard Z.: New Advances In Small Animal Imaging – CT. Small Animal Medicine Chapter, [in:] ACVSc College Science Week. Murdoch University 2008, p. 70-73.
• Lennox M. A., Chitty J.: Adrenal neoplasia and hyperplasia as a cause of hypertestosteronism in two rabbits. Journal Exot. Pet Med. 2006, 15, 56-58.
• Mapara M., Thomas B. S., Bhat K. M.: Rabbit as an animal model for experimental research. Dent. Res. J. 2012, 9, 111-118.
• O’Brien R. T., Paul-Murphy J., Dubielzig R. R.: Ultrasonography of adrenal glands in normal ferrets. Vet. Radiol. Ultrasound 1996, 37, 445-448.
• Okada M., Isoda T., Kumano S., Kagawa Y., Araki T., Onishi H., Hori M., Kim T., Motokui Y., Wada T., Murakami T.: Serine- and mannose-modified liposomal contrast agent for computed tomography: evaluation of the enhancement in rabbit liver VX-2 tumor model. Contrast Media Mol. I. 2010, 5, 140-146.
• Rabie F. O.: Morphological study of adrenal gland in prenatal and postnatal periods of domestic rabbit (Oryctolagus cuniculus). Bas. J. Vet. Res. 2013, 12, 253-264.
• Soler M., Murciano J., Latorre R., Belda E., Rodrıguez M., Agut A.: Ultrasonographic, computed tomographic and magnetic resonance imaging anatomy of the normal canine stifle joint. Vet. J. 2007, 174, 351-361.
• Stamatova-Yovcheva K.: The application of some imaging anatomical methods for investigation of the liver of the New Zealand white rabbit (Oryctolagus cuniculus). PhD thesis. Stara Zagora, Bulgaria 2016.
• StatSoft® Statistica 7: Descriptive statistic. Dell Software, USA 2013.
• Toru K., Brown M. S., Watanabe Y., Goldstein J. L.: Deficiency of low density lipoprotein receptors in liver and adrenal gland of the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc. Natl. Acad. Sci. 1981, 78, 2268-2272.
• Vitanov S., Dimitrov D., Bochukov A.: Methods for investigation in Cytology and Histology, [in:] Popova M. (ed.). Zemizdat EOOD, Sofia 1995, p. 3-22.
• Zatelli A., D’Ippolito P., Fiore I., Zini E.: Ultrasonographic evaluation of the size of the adrenal glands of 24 diseased cats without endocrinopathies. Vet. Rec. 2007, 160, 658-660.
• Zhang L., Duan Y., Yin J., Cui J., Zhang Y., Cao T.: Gray scale enhancement by a new self-made contrast agent in early cirrhotic stage of rabbit liver. BMC Gastroenterol. 2007, 7, 32.

Identyfikatory

DOI

10.21521/mw.6286