The effects of a highly chlorinated biphenyl—Delor 106—on the in vivo and in vitro luteinizing hormone secretion in female Prussian carp, Carassius gibelio (Actinopterygii: Cypriniformes: Cyprinidae)

• Autorzy: Socha M. , Sokolowska-Mikolajczyk M. , Szczerbik P. , Chyb J. , Gosiewski G.
• Języki publikacji: EN

Abstrakty

EN

Background. Endocrine disrupting chemicals (EDCs), among them polychlorinated biphenyls (PCBs), are able to change the hormonal regulation of reproduction at the hypothalamo-pituitary-gonadal (HPG) axis in many vertebrates. The aim of the presently reported study was to determine the effects of highly chlorinated PCBs mixture—Delor 106—on the in vivo and in vitro luteinizing hormone (LH) secretion from the pituitary gland of female Prussian carp, Carassius gibelio (Bloch, 1782), at the time of natural spawning. Materials and Methods. In the in vivo experiment we tested exposure to Delor 106: acute (one week at the concentration of 700 ng · L–1) and chronic (5 weeks at increasing weekly concentrations, from 140 through 700 ng · L–1). Blood samples from all females were taken before intoxication (0 week) and subsequently every week (week 1 through 5) till the end of the experiment. In the in vitro experiment enzymatically dispersed pituitary cells obtained from sexually mature Prussian carp females were incubated for 5 or 24 h in the presence of Delor 106 at the concentrations of: 1, 5, 10, 50, or 100 ng · mL–1 of medium. LH levels in the incubation medium as well as in blood plasma were measured using ELISA method. Results. Long-term (3 and 4 weeks) exposure to the Delor 106, gradually added to the water, caused a significant elevation of spontaneous LH secretion. Pituitary cells incubation with Delor 106 at the concentration range from 10 through 100 ng · mL–1 of medium resulted in the significant increase of spontaneous LH secretion after 5 and 24 h. Conclusion. The results obtained in this study show that highly chlorinated biphenyl—Delor 106—changes the secretion of luteinizing hormone in Prussian carp in the spawning season, acting, at least in part, directly at the pituitary level.

• Wydawca: -
• Czasopismo: Acta Ichthyologica et Piscatoria
• Rocznik: 2013
• Tom: 43
• Numer: 3
• Opis fizyczny: p.195-200,fig.,ref.

Twórcy

autor

Socha M.

• Agricultural University in Krakow, Prof. T. Spiczakowa 6, 30-199 Krakow, Poland

autor

Sokolowska-Mikolajczyk M.

• Department of Ichthyobiology and Fisheries, University of Agriculture, Krakow, Poland

autor

Szczerbik P.

• Department of Ichthyobiology and Fisheries, University of Agriculture, Krakow, Poland

autor

Chyb J.

• Department of Ichthyobiology and Fisheries, University of Agriculture, Krakow, Poland

autor

Gosiewski G.

• Department of Ichthyobiology and Fisheries, University of Agriculture, Krakow, Poland

Bibliografia

• Andric N.L., Kostic T.S., Zoric S.N., Stanic B.D., Andric S.A.,Kovacevic R.Z. 2006. Effect of a PCB-based transformer oil on testicular steroidogenesis and xenobiotic-metabolizing enzymes. Reproductive Toxicology 22 (1): 102–110.DOI: 10.1016/j.reprotox.2005.12.002
• Benninghoff A.D., Thomas P. 2005. Involvement of calcium and calmodulin in the regulation of ovarian steroidogenesis in Atlantic croaker (Micropogonias undulatus) and modulation by Aroclor 1254. General and Comparative Endocrinology 144 (3): 211–223. DOI: 10.1016/j.ygcen.2005.06.005
• Buchanan D.L., Sato T., Peterson R.E., Cooke P.S. 2000.Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse uterus: Critical role of the aryl hydrocarbon receptor in stromal tissue. Toxicological Sciences 57 (2):302–311. DOI: 10.1093/toxsci/57.2.302
• Coimbra A.M., Reis-Henriques M.A. 2007. Tilapia larvae Aroclor 1254 exposure: Effects on gonads and circulating thyroid hormones during adulthood. Bulletin of Environmental Contamination and Toxicology 79 (5):488–493. DOI: 10.1007/s00128-007-9288-2
• Coimbra A.M., Reis-Henriques M.A., Darras V.M. 2005.Circulating thyroid hormone levels and iodothyronine deiodinase activities in Nile tilapia (Oreochromis niloticus) following dietary exposure to Endosulfan and Aroclor 1254.Comparative Biochemistry and Physiology Part C:Toxicology and Pharmacology 141 (1): 8–14. DOI:10.1016/j.cca.2005.04.006
• Daouk T., Larcher T., Roupsard F., Lyphout L., Rigaud C.,Ledevin M., Loizeau V., Cousin X. 2011. Long-term foodexposure of zebrafish to PCB mixtures mimicking some environmental situations induces ovary pathology and impairs reproduction ability. Aquatic Toxicology 105 (3–4):270–278. DOI: 10.1016/j.aquatox.2011.06.021
• Desaulniers D., Leingartner K., Wade M., Fintelman E.,Yagminas A., Foster W.G. 1999. Effects of acute exposure to PCBs 126 and 153 on anterior pituitary and thyroid hormonem and FSH isoforms in adult Sprague Dawley male rats. Toxicology Sciences 47 (2): 158–169. DOI:10.1093/toxsci/47.2.158
• Desotelle J., Splett C., Scheffen J. 2005. PCB exposure alters anterior pituitary sensitivity to gonadotropin-releasing hormone (GnRH) in adult female rats. Bios 76 (2): 68–76. DOI:10.1893/0005-3155(2005)076[0068:RAPEAA]2.0.CO;2
• Dickerson S.M., Gore A.C. 2007. Estrogenic environmental endocrine-disrupting chemical effects on reproductive neuroendocrine function and dysfunction across the life cycle.Reviews in Endocrine and Metabolic Disorders 8 (2):143–159. DOI: 10.1007/s11154-007-9048-y
• Gore A.C., Wu T.J., Oung T., Lee J.B., Woller M.J. 2002.A novel mechanism for endocrine-disrupting effects of polychlorinated biphenyls: Direct effects on gonadotropinreleasing hormone neurones. Journal of Neuroendocrinology 14 (10): 814–823. DOI: 10.1046/j.1365-2826.2002.00845.x
• Grabic R.,Hansen L.G., Ptak A.,Crhova S.,Gregoraszczuk E.Ł.2006. Differential accumulation of low-chlorinated (Delor 103) and high-chlorinated (Delor 106) biphenyls in human placental tissue and opposite effects on conversion of DHEA to E2. Chemosphere 62 (4): 573–580. DOI: 10.1016/j.chemosphere.2005.06.027
• Gregoraszczuk E.L., Ptak A., Karniewska M., Ropstad E. 2008. Action of defined mixtures of PCBs, p,p′-DDT and its metabolite p,p′-DDE, on co-culture of porcine theca and granulosa cells: Steroid secretion, cell proliferation and apoptosis. Reproductive Toxicology 26 (2): 170–174. DOI:10.1016/j.reprotox.2008.07.003
• Gregoraszczuk E., Zemla M., Ptak A., Grabic R. 2005. The action of low- and high-chlorinated biphenyl mixture on the prepubertal porcine ovary: Steroid secretion and cell apoptosis.Endocrine Regulation 39 (2): 33–41.
• Jablonska O., Piasecka J., Petroff B.K., Nynca A., Siawrys G.,Wąsowska B., Zmijewska A., Lewczuk B., Ciereszko R.E.2011. In vitro effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on ovarian, pituitary, and pineal function in pigs.Theriogenology 76 (5): 921–932. DOI: 10.1016/j.theriogenology.2011.04.023
• Jansen H.T., Cooke P.S., Porcelli J., Liu T.-C., Hansen L.G.1993. Estrogenic and antiestrogenic actions of PCBs in the female rat: In vitro and in vivo studies. Reproductive Toxicology 7 (3): 237–248. DOI: 10.1016/0890-6238 (93)90230-5
• Kah O.,Anglade I.,Linard B.,Pakdel F., Salbert G.,Bailhache T.,Ducouret B., Saligaut C., Le Goff P., Valotaire Y., Jégo P.1997. Estrogen receptors in the brain-pituitary complex and the neuroendocrine regulation of gonadotropin release in rainbow trout. Fish Physiology and Biochemistry 17 (1–6): 53–62.DOI: 10.1023/A:1007749715473
• Kah O., Ponent A., Rodriguez J.N., Calas A., Breton B. 1989.Development of enzyme-linked immunosorbent assay for goldfish gonadotropin. Biology of Reproduction 40: 68–73.DOI: 10.1095/biolreprod41.1.68
• Kazuń K., Siwicki A.K. 2012. Propiscin – a safe new anaesthetic for fish. Archives of Polish Fisheries 20 (173–177). DOI:10.2478/v10086-012-0021-3
• Kester M.H.A., Bulduk S., Tibboel D., Meinl W., Glatt H.,Falany C.N., Coughtrie M.W.H., Bergman A., Safe S.H.,Kuiper G.G.J.M., Schuur A.G., Brouwer A., Visser T.J.2000. Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: A novel pathway explaining the estrogenic activity of PCBs. Endocrinology 141 (5):1897–1900. DOI: 10.1210/en.141.5.1897
• Khan I.A.,Mathews S., Okuzawa K., Kagawa H., Thomas P.2001. Alterations in the GnRH-LH system in relation to gonadal stage and Aroclor 1254 exposure in Atlantic croaker.Comparative Biochemistry and Physiology Part B:Biochemistry and Molecular Biology 129 (2–3): 251–259.DOI: 10.1016/S1096-4959(01)00318-9
• Khan I.A., Thomas P. 2001. Disruption of neuroendocrine control of luteinizing hormone secretion by Aroclor 1254 involves inhibition of hypothalamic tryptophan hydroxylase activity. Biology of Reproduction 64 (3): 955–964. DOI:10.1095/biolreprod64.3.955
• Khan I.A., Thomas P. 2006. PCB congener-specific distribution of reproductive neuroendocrine function in Atlantic croaker. Marine Environmental Research 62 (Suppl. 1):S25–S28. DOI: 10.1016/j.marenvres.2006.04.029
• Kotwica J.,Wróbel M.,Młynarczuk J. 2006. The influence of polychlorinated biphenyls (PCBs) and phytoestrogens In vitro on functioning of reproductive tract in cow. Reproductive Biology 6 (Suppl. 1): 189–94.
• KraugerudM., AleksandersenM., Nyengaard J.R.,OstbyG.C.,Gutleb A.C., Dahl E., Berg V., Farstad W., Schweder T., Skaare J.U., Ropstad E. 2012a. In utero and lactational exposure to PCB 118 and PCB 153 alter ovarian follicular dynamics and GnRH-induced luteinizing hormone secretion in female lambs. Environmental Toxicology 27 (11):623–634. DOI: 10.1002/tox.20679
• Kraugerud M., Doughty R.W., Lyche J.L., Berg V.,Tremoen N.H., AlestromP., Aleksandersen M., Ropstad E.2012b. Natural mixtures of persistent organic pollutants (POPs) suppress ovarian follicle development, liver vitellogenin immunostaining and hepatocyte proliferation In female zebrafish (Danio rerio). Aquatic Toxicology 116–117: 16–23. DOI: 10.1016/j.aquatox.2012.02.031
• Lambooij B., Pilarczyk M., Białowas H., Reimert H., André G.,Van De Vis H. 2009. Anaesthetic properties of Propiscin (Etomidaat) and 2-phenoxyethanol in the common carp (Cyprinus carpio L.), neural and behavioural measures.Aquaculture Research 40 (11): 1328–1333. DOI:10.1111/j.1365-2109.2009.02233.x
• Li X., Johnson D.C., Rozman K.K. 1997. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) increases release of luteinizing hormone and follicle-stimulating hormone from the pituitary of immature female rats in vivo and in vitro.Toxicology and Applied Pharmacology 142 (2): 264–269.DOI: 10.1006/taap.1996.8044
• Mikolajczyk T., Weil C., Epler P., Breton B. 1990.Involvement of voltage-dependent calcium channels (VDCC) in the action of GnRH on GtH release in common carp (Cyprinus carpio L): comparison with K+ action.Reproduction Nutrition Development 30 (5): 619–628. DOI:10.1051/rnd:19900507
• Młynarczuk J., Kotwica J. 2006. Influence of polychlorinated biphenyls on LH-stimulated secretion of progesterone and oxytocin from bovine luteal cells. Polish Journal of Veterinary Sciences 9 (2): 101–108.
• Muriach B., Carrillo M., Zanuy S., Cerdá-Reverter J.M.2008. Distribution of estrogen receptor 2 mRNAs (Esr2a
• and Esr2b) in the brain and pituitary of the sea bass (Dicentrarchus labrax). Brain Research 1210: 126–141.DOI: 10.1016/j.brainres.2008.02.053
• Oskam I.C., Lyche J.L., Krogenas A., Thomassen R.,Skaare J.U., Wiger R., Dahl E., Sweeney T., Stien A.,
• Ropstad E. 2005. Effects of long-term maternal exposure to low doses of PCB126 and PCB153 on the reproductive system and related hormones of young male goats.Reproduction 130 (5): 731–742. DOI: 10.1530/rep.1.00690
• Petroff B.K., Croutch C.R., Hunter D.M., Wierman M.E.,Gao X. 2003. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) stimulates gonadotropin secretion in the immature female Sprague-Dawley rat through a pentobarbital- and estradiolsensitive mechanism but does not alter gonadotropin-releasing hormone (GnRH) secretion by immortalized GnRH neurons in vitro. Biology of Reproduction 68 (6): 2100–2106.DOI: 10.1095/biolreprod.102.010439
• Plíšková M., Vondráček J., Canton R.F., Nera J., Kočan A.,Petrík J., Trnovec T., Sanderson T., van den Berg M.,Machala M. 2005. Impact of polychlorinated biphenyls contamination on estrogenic activity in human male serum.Environmental Health Perspectives 113 (10): 1277–1284.DOI: 10.1289/ehp.7745
• Socha M., Sokołowska-Mikołajczyk M., Szczerbik P., Chyb J.,Mikołajczyk T., Epler P. 2012. The effect of polychlorinated biphenyls mixture (Aroclor 1254) on the embryonic development and hatching of Prussian carp, Carassius gibelio, and common carp, Cyprinus carpio (Actinopterygii:Cypriniformes: Cyprinidae). Acta Ichthyologica et Piscatoria 42 (1): 31–35. DOI: 10.3750/AIP2011.42.1.04
• Socha M., Sokolowska-Mikolajczyk M., Szczerbik P., Chyb J.,Dietrich G., Kowalski R., Grabic R., Epler P. 2008a. The influence of polychlorinated biphenyls (PCBs) on komputer analysed spermmotility of common carp (Cyprinus carpio L.)in vitro. Cybium 32 (Suppl. 2): 197.
• Socha M., Sokołowska-Mikołajczyk M., Szczerbik P.,Mikołajczyk T., Chyb J., Duc M., Epler P. 2008b. Effect of Aroclor 1254 (PCB) on spontaneous and sGnRHa- stimulated LH secretion from male and female carp (Cyprinus carpio L.) pituitary gland. p. 142. In: Proceeding 6th International Symposium of Fish Endocrinology, 22–27 June 2008, Calgary, Canada.
• Taniyasu S., Kannan K., Holoubek I., Ansorgova A., Horii Y.,Hanari N., Yamashita N., Aldous K.M. 2003. Isomer-specific analysis of chlorinated biphenyls, naphthalenes and dibenzofurans in Delor: polychlorinated biphenyl preparations from the former Czechoslovakia. Environmental Pollution 126 (2): 169–178. DOI: 10.1016/S0269-7491(03)00207-0
• Thomas P., Doughty K. 2004. Disruption of rapid, nongenomic steroid actions by environmental chemicals: Interferencje with progestin stimulation of sperm motility in Atlantic croaker. Environmental Science and Technology 38 (23):6328–6332. DOI: 10.1021/es0403662
• Van Geest J.L., Mackay D., Poirier D.G., Sibley P.K.,Solomon K.R. 2011. Accumulation and depuration of polychlorinated biphenyls from field-collected sediment in three freshwater organisms. Environmental Science and Technology 45 (16): 7011–7018. DOI: 10.1021/es1043744
• Wójtowicz A.K., Goch M., Gregoraszczuk E.L. 2005.Polychlorinated biphenyls (PCB 153 and PCB 126) action on conversion of 20-hydroxylated cholesterol to progesterone,androstenedione to testosterone, and testosterone to estradiol 17beta. Experimental and Clinical Endocrinology and Diabetes 113 (8): 464–470. DOI: 10.1055/s-2005-865776
• Wójtowicz A.K., Gregoraszczuk E.L., Lyche J.L., Ropstad E.2000. Time dependent and cell-specific action of polychlorinated biphenyls (PCB 153 and PCB 126) on steroid secretion by porcine theca and granulosa cells in mono- and coculture.Journal of Physiology and Pharmacology 51 (3): 555–568.
• Yamamoto M., Narita A., Kagohata M., Shirai M., Akahori F.,Aroshima K. 2005. Effects of maternal exposure to 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) or 3,3′,4,4′,5,5′-hexachlorobiphenyl (PCB169) on testicular steroidogenesis and spermatogenesis in male offspring rats. Journal of Andrology 26 (2): 205–214. DOI: 10.1002/j.1939-4640.2005.tb01087.x
• Yano T., Matsuyama H. 1986. Stimulatory effect of PCB on the metabolism of sex hormones in carp hepatopancreas.Bulletin of the Japanese Society of Scientific Fisheries 52 (10): 1847–1852.

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