Role of insulin during the development of oligofructose (OF)-induced equine laminitis

• Autorzy: Jiang R. , Gao L. , Wang G. , Li X. , Li Y. , Fan X. , Liu X. , Wang J. , Zhang Y. , Kong X. , Xiao J.
• Języki publikacji: EN

Abstrakty

EN

Horses (n = 20) were divided into 2 groups: oligofructose (OF)-induced equine laminitis group (group OF; n = 11) which received 10 g/kg b.w. of OF dissolved in 4 L water via nasogastric intubation, and control group (NS; n = 9) which received 4 L of saline. Blood was collected at 4 h intervals over 72 h study period and analysed by ELISA, kinetic limulus amoebocvte lysate assay, and glucose-oxidase methods. The level of insulin changed significantly in horses which received OF (P < 0.01); there was a significant negative correlation between the level of adiponectin and insulin over time. The results suggested that insulin may play an important role in the development of OF-induced equine laminitis by altering the level of endothelin-1 and nitric oxide.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2015
• Tom: 59
• Numer: 2
• Opis fizyczny: p.303-309,fig.,ref.

Twórcy

autor

Jiang R.

• Department of Hygiene of Food of Animal Origin, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China

autor

Gao L.

• Department of Hygiene of Food of Animal Origin, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China

autor

Wang G.

• Department of Hygiene of Food of Animal Origin, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China

autor

Li X.

• Department of Hygiene of Food of Animal Origin, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China

autor

Li Y.

• Department of Hygiene of Food of Animal Origin, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China

autor

Fan X.

• Department of Hygiene of Food of Animal Origin, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China

autor

Liu X.

• Department of Hygiene of Food of Animal Origin, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China

autor

Wang J.

• Department of Hygiene of Food of Animal Origin, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China

autor

Zhang Y.

• Department of Hygiene of Food of Animal Origin, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China

autor

Kong X.

• Department of Hygiene of Food of Animal Origin, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China

autor

Xiao J.

• Department of Hygiene of Food of Animal Origin, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China

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Identyfikatory

DOI

10.1515/bvip-2015-0044