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2013 | 73 | 3 |

Tytuł artykułu

Distinct neural signatures of cognitive subtypes of dyslexia: Effects of lexicality during phonological processing

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The present study investigates the neurobiological basis of two subtypes of dyslexia with either a double deficit (concerning phonological awareness and rapid naming) or a single rapid naming deficit. We compared such groups of German dyslexic primary school children to each other and with good reading children in a phoneme deletion task performed during fMRI scanning. Children heard German words or pseudowords and repeated the remainder of the stimulus while deleting the initial phoneme (e.g. tear - _ear). In four conditions, the input stimulus (word or pseudoword) could either become another word or pseudoword as output. The word-word condition stuck out against all other conditions involving pseudowords: Dyslexics with a double deficit showed a strong response in left areas 44 and 45 in Boca's region, whereas dyslexics with rapid naming difficulties revealed a contralateral effect in right areas 44 and 45. These findings, which were obtained without presenting written or pictorial stimuli, reveal that a double deficit in dyslexia is not the sum of single deficits, but rather involves the interaction of lexical and phonological processing, making strong demands on the left inferior frontal cortex. In general, the results stress the importance of considering subtypes of dyslexia differentially in order to obtain better insights in the neurocognitive mechanisms of impaired and successful reading.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

73

Numer

3

Opis fizyczny

p.404-416,fig.,ref.

Twórcy

  • Department of Psychiatry, Psychotherapy and Psychosomatics, Medical School, Section Structural-Functional Brain Mapping, RWTH Aachen University, Aachen, Germany
  • JARA-Translation Brain Medicine, Julich and Aachen, Germany
  • Department of Neurology, Medical School, Section Neurological Cognition Research, RWTH Aachen University, Aachen, Germany
autor
  • JARA-Translation Brain Medicine, Julich and Aachen, Germany
  • Department of Neurology, Medical School, Section Neurological Cognition Research, RWTH Aachen University, Aachen, Germany
autor
  • Department of Psychophysiology, Nencki Institute of Experimental Biology, PAS, Warsaw, Poland
  • Warsaw School of Social Psychology and Humanities, Warsaw, Poland
autor
  • Department of Psychiatry, Psychotherapy and Psychosomatics, Medical School, Section Structural-Functional Brain Mapping, RWTH Aachen University, Aachen, Germany
  • JARA-Translation Brain Medicine, Julich and Aachen, Germany
  • Department of Neurology, Medical School, Section Neurological Cognition Research, RWTH Aachen University, Aachen, Germany
  • Institute of Neuroscience and Medicine (INM-1), Research Centre Julich, Julich, Germany

Bibliografia

  • Amunts K, Schleicher A, Bürgel U, Mohlberg H, Uylings HB, Zilles K (1999) Broca's region revisited: cytoarchitecture and intersubject variability. J Comp Neurology 412: 319-341.
  • Amunts K, Weiss PH, Mohlberg H, Pieperhoff P, Eickhoff S, Gurd JM, Marshall JC, Shah NJ, Fink GR, Zilles K (2004) Analysis of neural mechanisms underlying verbal fluency in cytoarchitectonically defined stereotaxic space- -the roles of Brodmann areas 44 and 45. Neuroimage 22: 42-56.
  • Bitan T, Burman DD, Lu D, Cone NE, Gitelman DR, Mesulam MM, Booth JR (2006) Weaker top-down modu¬lation from the left inferior frontal gyrus in children. Neuroimage 33: 991-998.
  • Burton MW, Small SL, Blumstein SE (2000) The role of segmentation in phonological processing: an fMRI inves¬tigation. J Cogn Neurosci 12: 679-690.
  • Bosse ML, Tainturier MJ, Valdois S (2007) Developmental dyslexia: the visual attention span deficit hypothesis. Cognition 104: 198-230.
  • Cao F, Bitan T, Chou TL, Burman DD, Booth JR (2006) Deficient orthographic and phonological representations in children with dyslexia revealed by brain activation pat¬terns. J Child Psychol Psychiatry 47: 1041-1050.
  • Critchley M (1970) The Dyslexic Child (2nd ed.). Heinemann Medical Books, London, UK.
  • Eickhoff SB, Stephan KE, Mohlberg H, Grefkes C, Fink GR, Amunts K, Zilles K (2005) A new SPM toolbox for combining probabilistic cytoarchitectonic maps and func¬tional imaging data. Neuroimage 25: 1325-1335.
  • Fiebach CJ, Friedend AD, Müller K, von Cramon DY (2002) fMRI evidence for dual routes to the mental rec¬ognition. J Cogn Neurosci 14: 11-23.
  • Francis DJ, Shaywitz SE, Stuebing KK, Shaywitz BA, Fletcher JM (1994) The measurement of change: Assessing behavior over time and within a developmental context. In: Frames of Reference for the Assessment of Learning Disabilities: New Views on Measurement Issues (Lyon R, Ed.). Paul H Brookes Publishing, Baltimore, MD, p. 29-58.
  • Georgiewa P, Rzanny R, Hopf JM, Knab R, Glauche V, Kaiser WA, Blanz B (1999) fMRI during word processing in dyslexic and good reading children. Neuroreport 10: 3459-3465.
  • Georgiewa P, Rzanny R, Gaser C, Gerhard UJ, Vieweg U, Freesmeyer D, Mentzel HJ, Kaiser WA, Blanz B (2002) Phonological processing in dyslexic children: a study combining functional imaging and event related poten¬tials. Neurosci Lett 318: 5-8.
  • Grande M, Meffert E, Huber W, Amunts K, Heim S (2011) Word frequency effects in the left IFG in dyslexic and good reading children during picture naming and reading. Neuroimage 57: 1212-1220.
  • Häussler T, Sturm W (2009) Construct validation of a novel test battery for perception and attention (in German). Z Neuropsychol 20: 324-339.
  • Heim S, Alter K, Ischebeck AK, Amunts K, Eickhoff SB, Mohlberg H, Zilles K, von Cramon DY, Friederici AD (2005) The role of the left Brodmann's areas 44 and 45 in reading words and pseudowords. Brain Res Cogn Brain Res 25: 982-993.
  • Heim S, Eickhoff S, Opitz B, Friederici AD (2006) BA 44 in Broca's area supports grammatical gender decisions in language production. Neuroreport 17: 1097-1101.
  • Heim S, Tschierse J, Amunts K, Wilms M, Vossel S, Willmes K, Grabowska A, Huber W (2008) Cognitive subtypes of dyslexia. Acta Neurobiol Exp (Wars) 68: 73-82.
  • Heim S, Eickhoff SB, Friederici AD, Amunts K (2009a) Left cytoarchitectonic area 44 supports selection in the mental lexicon during language production. Brain Struct Func 213: 441-456.
  • Heim S, Eickhoff SB, Ischebeck AK, Friederici AD, Stephan KE, Amunts K (2009b) Effective connectivity of the left BA 44, BA 45, and inferior temporal gyrus during lexical and phonological decisions identified with DCM. Hum Brain Mapp 30: 392-402.
  • Heim S, Grande M, Pape-Neumann J, van Ermingen M, Meffert E, Grabowska A, Huber W, Amunts K (2010a) Interaction of phonological awareness and ,magnocellu- lar' processing during normal and dyslexic reading: behavioural and fMRI investigations. Dyslexia 16: 258¬282.
  • Heim S, Grande M, Meffert E, Eickhoff SB, Schreiber H, Kukolja J, Shah NJ, Huber W, Amunts K (2010b) Cognitive levels of performance account for hemispheric lateralisation effects in dyslexic and good reading chil¬dren. Neuroimage 53: 1346-1358.
  • Heim S, Wehnelt A, Grande M, Huber W, Amunts K (2013) Effects of lexicality and word frequency on brain activation in dyslexic readers. Brain Lang 125:194-202.
  • Hoeft F, Hernandez A, McMillon G, Taylor-Hill H, Martindale JL, Meyler A, Keller TA, Siok WT, Deutsch GK, Just MA, Whitfield-Gabrieli S, Gabrieli JDE (2006) Neural basis of dyslexia: a comparison between dyslexic and nondyslexic children equated for reading ability. J Neurosci 26: 10700-10708.
  • Hoeft F, Melyer A, Hernadez A, Juel C, Taylor-Hill H (2007) Functional and morphometric brain dissociation between dyslexia and reading ability. Proc Natl Acad Sci U S A 104: 4234-4239.
  • Kronbichler M, Hutzler F, Wimmer H, Mair A, Staffen W, Ladurner G (2004) The visual word form area and the frequency with which words are encountered: evidence from a parametric fMRI study. Neuroimage 21: 946-953.
  • Liberman, IY (1973) Segmentation of the spoken word and reading aquisition. Ann Dyslexia 28: 1238-1250.
  • Lymberis J, Christodoulou JA, O'Loughlin P, Del Tufo S, Gabrieli JDE (2009) Neural correlates of rapid automa¬tized naming. 39th Annual Meeting of the Society for Neuroscience, Chicago IL. [http://web.mit.edu/tkp/www/ Lymberis_etal_SfN-2009.pdf]
  • Lyon GR, Shaywitz SE, Shaywitz BA (2003) A definition of dyslexia. Ann Dyslexia 53: 1-14.
  • Mayer A (2008) Phonological Awareness, Naming Speed, and Automatised Reading Processes (in German). Shaker, Aachen DE.
  • Mayringer H, Wimmer H (2003) Salzburg Reading Screening for Grades 1-4 (in German). Hans Huber, Bern, CH.
  • Mechelli A, Crinion JT, Long S, Friston KJ, Lambon R, Patterson K, McClelland JL, Price CJ (2005) Dissociating reading processes on the basis of neuronal interactions. J Cogn Neurosci 17: 1753-1765.
  • Misra M, Katzir T, Wolf M, Poldrack RA (2004). Neural systems for rapid automatized naming in skilled readers: unraveling the RAN-reading relationship. Sci Studies Read 8: 241-256.
  • Poldrack RA, Wagner AD, Prull MW, Desmond JE, Glover GH, Gabrieli JD (1999) Functional specialization for semantic and phonological processing in the left inferior prefrontal cortex. Neuroimage 10: 15-35.
  • Ramus F (2003) Developmental dyslexia: specific phono¬logical deficit or general sensorimotor dysfunction? Curr Opin Neurobiol 13: 212-218.
  • Ramus F (2004) Neurobiology of dyslexia: a reinterpretation of the data. Trends Neurosci 27: 720-726.
  • Ramus F, Ramus F, Rosen S, Dakin SC, Day BL, Castellote JM, White S, Frith U (2003) Theories of developmental dyslexia: insights from a multiple case study of dyslexic adults. Brain 126: 841-865.
  • Richlan F (2012) Developmental dyslexia: dysfunction of a left hemisphere reading network. Front Hum Neurosci 6: 120
  • Richlan F, Kronbichler M, Wimmer H (2009) Functional abnormalities in the dyslexic brain: A quantitative meta- analysis of neuroimaging studies. Hum Brain Mapp 30: 3299-3308.
  • Richlan F, Kronbichler M, Wimmer H (2011) Meta-analyzing brain dysfunctions in dyslexic children and adults. Neuroimage 56: 1735-1742.
  • Rumsey JM, Nace K, Donohue B, Wise D, Maisog M, Andreason P (1997) A positron emission tomographic study of impaired word recognition and phonological processing in dyslexic men. Arch Neurol 54: 562-573.
  • Schleicher A, Palomero-Gallagher N, Morosan P, Eickhoff SB, Kowalski T, Vos K de, Amunts K, Zilles, K (2005) Quantitative architectural analysis: a new approach to cortical mapping. Anat Embryol 210: 373-386.
  • Shaywitz S (1998) Dyslexia. New Engl J Med 338: 307¬312.
  • Shaywitz S (2005) Overcoming Dyslexia a New and Complete Science-Based Program for Reading Problems at Any Level. Vintage Books, New York, NY.
  • Shaywitz B, Holford T, Holahan J, Fletcher J, Stuebing K, Francis D, Shaywitz SE (1995) A Matthew effect for IQ but not for reading: results from a longitudinal study. Read Res Quart 4: 894-906.
  • Shaywitz BA, Shaywitz SE, Pugh KR, Mencl WE, Fulbright RK, Skudlarski P, Constable RT, Marchione KE, Fletcher JM, Lyon GR, Gore JC (2002) Disruption of posterior brain systems for reading in children with developmental dyslexia. Biol Psychiatry 52: 101-110.
  • Snowling MJ (1995) Phonological processing and develop¬mental dyslexia. J Res Readi 18: 132-138.
  • Snowling MJ (2000) Dyslexia (2 ed.). Blackwell Publishers, Oxford, UK.
  • Steinbrink C, Ackermann H, Lachmann T, Riecker A (2009) Contribution of the anterior insula to temporal auditory processing deficits in developmental dyslexia. Hum Brain Mapp 30: 2401-2411.
  • Steinbrink C, Groth K, Lachmann T, Riecker A (2012) Neural correlates of temporal auditory processing in developmental dyslexia during German vowel length discrimination: An fMRI study. Brain Lang 121: 1-11.
  • Stock C, Marx P, Schneider W (2003) Basic Competences for Reading and Writing. An Assessment for Phonological Awareness in Grades 1-4 (in German). Hogrefe, Göttingen, DE.
  • Temple E, Poldrack RA, Salidis J, Deutsch G, Tallal P, Merzenich MM, Gabrieli JD (2001) Disrupted neural responses to phonological and orthographic processing in dyslexic children: an fMRI study. Neuroreport 12: 299¬307.
  • Tholen N, Weidner R, Grande M, Amunts K, Heim S (2011) Eliciting dyslexic symptoms in proficient readers by simulating deficits in grapheme-to-phoneme conversion and visuo-magnocellular processing. Dyslexia 17: 268¬281.
  • van Ermingen-Marbach M, Grande M, Pape-Neumann J, Sass K, Heim S (2013) Distinct neural signatures of cog¬nitive subtypes of dyslexia with and without phonological deficits. Neuroimage Clin 2: 477-490.
  • Valdois S, Bosse ML, Ans B, Carbonnel S, Zorman M, David D, Pellat J (2003) Phonological and visual process¬ing deficit can dissociate in developmental dyslexia: Evidence from two case studies. Read Writ 16: 541-572.
  • Vellutino FR, Fletcher JM, Snowling M J, Scanlon DM (2004) Specific reading disability (dyslexia): what have we learned in the past four decades? J Child Psychol Psychiatry 45: 2-40.
  • Verhalen N (2011) "Rapid automatised naming" in normally reading children in grade 4 (in German) (Master thesis). RWTH Aachen University, Aachen, DE.
  • Wagner AD, Desmond JE, Demb JB, Glover GH, Gabrieli JDE (1997) Semantic repetition priming for verbal and pictorial knowledge: A functional mri study of left infe¬rior prefrontal cortex. J Cogn Neurosci 9: 714-726.
  • Wagner RK, Torgesen, JK (1987) The nature of phonologi¬cal processing and its causal role in the acquisition of reading skills. Psychol Bull 101: 192-212.
  • Wagner RK, Torgesen JK, Rashotte CA, Hecht SA, Barker TA, Burgess SR, Donahue J, Garon T (1997) Changing relations between phonological processing abilities and word-level reading as children develop from beginning to skilled readers: A 5-year longitudinal study. Dev Psychol 33: 468-479.
  • Weiss RH (1998) Basic Intelligence Scale 2 with Tests for Vocabulary and Number Order: Manual (in German). Westermann, Gottingen, DE.
  • Wimmer H, Schurz M, Sturm D, Richlan F, Klackl J, Kronbichler M, Ladurner G (2010) A dual-route perspec¬tive on poor reading in a regular orthography: An fMRI study. Cortex 46: 1284-1298.
  • Wolf M, Bowers PG (1999) The double-deficit hypothesis for the developmental dyslexias. ournal of Educational Psychology 91: 415-438.
  • Zatorre RJ, Evans AC, Meyer E, Gjedde A (1992) Lateralization of phonetic and pitch discrimination in speech processing. Science 256: 846-849.
  • Zatorre RJ, Meyer E, Gjedde A, Evans AC (1996) PET Studies of Phonetic Processing of Speech: Review, Replication, and Reanalysis. Cereb Cortex 6: 21-30.
  • Zilles K, Schleicher A, Palomero-Gallaher N, Amunts K (2002) Quantitative analysis of cyto- and receptor archi¬tecture of the human brain. In Brain Mapping: The Methods (Mazziotta JC, Toga AW, Eds). Elsevier, Amsterdam, NL, p. 573-602.

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