Plants as potential active components in treatment of androgenetic alopecia

• Autorzy: Dawid-Pac R. , Urbanska M. , Debosz I. , Nowak G.

Warianty tytułu

PL

Surowce roślinne jako potencjalne składniki aktywne w terapii łysienia androgenowego

• Języki publikacji: EN

Abstrakty

EN

Androgenetic alopecia is caused by the influence of sex hormones on hair follicles and by hereditary factors. Characteristic for that type of alopecia is shortening of the hair growth phase and elongation of the rest phase caused by disturbance of the process of transformation of testosterone into dihydrotestosterone. Treatment of that type of alopecia involves 5α-reductase inhibitors, antagonists of the androgenic receptor or stimulating proliferation of cells to induce the hair growth. A number of plant raw materials work that way, thus they can be used in treatment of this type of alopecia.

PL

Łysienie androgenowe spowodowane jest wpływem hormonów płciowych na mieszki włosowe oraz czynnikami dziedzicznymi. W przebiegu tego typu łysienia charakterystyczne jest skrócenie fazy wzrostu włosa i wydłużenie fazy spoczynku, spowodowane zaburzeniem procesu przekształcania testosteronu w dihydrotestosteron. W terapii tego typu łysienia stosuje się inhibitory 5α-reduktazy, antagonistów receptora androgenowego lub stymuluje proliferację komórek, w celu przyśpieszenia wzrostu włosa. Wiele surowców roślinnych działa według powyższych mechanizmów, dlatego mogą być wykorzystane w terapii tego typu łysienia.

• Wydawca: -
• Czasopismo: Herba Polonica
• Rocznik: 2014
• Tom: 60
• Numer: 1
• Opis fizyczny: p.49-56,ref.

Twórcy

autor

Dawid-Pac R.

• Department of Medicinal and Cosmetic Natural Products, Poznan University of Medical Sciences, Mazowiecka 33, 60-623 Poznan, Poland

autor

Urbanska M.

• Department of Medicinal and Cosmetic Natural Products, Poznan University of Medical Sciences, Mazowiecka 33, 60-623 Poznan, Poland

autor

Debosz I.

• Department of Medicinal and Cosmetic Natural Products, Poznan University of Medical Sciences, Mazowiecka 33, 60-623 Poznan, Poland

autor

Nowak G.

• Department of Medicinal and Cosmetic Natural Products, Poznan University of Medical Sciences, Mazowiecka 33, 60-623 Poznan, Poland

Bibliografia

• 1. Brzezińska-Wcisło L, Lis A, Kamińska G, Wcisło-Dziadecka D. [Physiology and pathology of growth and loss of human scalp hair]. Post Dermatol Alergol 2003; 20(5):260-266.
• 2. Özcan D, Özen Ö, and Seçkin D. Vertical vs. transverse sections of scalp biopsy specimens: a pilot study on the comparison of the diagnostic value of two techniques in alopecia. Clin Exp Dermatol 2011; 36:855-863.
• 3. Socha K, Markiewicz R, Borawska MH. [The treatment of hair loss and dandruff]. Dermatol Estet 2007; 2(49):105-109.
• 4. Kruś S, Arct J, Pytkowska K, Majewski S. [Regulation of human hair growth by cosmetics – facts and myths]. Dermatol Estet 2007; 6(53):367-377.
• 5. Blume-Peytavi U, Blumeyer A, Tosti A Finner A, Marmol V, Trakatelli M. S1 guideline for diagnostic evaluation in androgenetic alopecia in men, women and adolescents. Br J Dermatol 2010; 164:5-15.
• 6. Aburjai T, Natsheh F. Plants used in cosmetics. Phytother Res 2003; 17(9):987-1000.
• 7. Messenger A. Male Androgenetic Alopecia. In: Blume-Peytavi U, Tosti A, Whiting DA, Trűeb RM (eds). Hair Growth and Disorders. Berlin, Springer-Verlag, 2008:166-168.
• 8. Park WS, Lee CH, Lee BG, Chang IS. The extract of Thujae occidentalis semen inhibited 5alpha-reductase and androchronogenetic alopecia of B6CBAF1/j hybrid mouse. J Dermatol Sci 2003; 31(2):91-98.
• 9. Roh SS, Kim CD, Lee MH, Hwang SL, Rang MJ, Yoon YK. The hair growth promoting effect of Sophora flavescens extract and its molecular regulation. J Dermatol Sci 2002; 30(1):43-49.
• 10. Matsuda H, Yamazaki M, Matsuo K, Asanuma Y, Kubo M. Anti-androgenic activity of Myricae Cortexisolation of active constituents from bark of Myrica rubra. Biol Pharm Bull 2001; 24 (3):259-263.
• 11. Hirata N, Tokunaga M, Naruto S, Iinuma M, Matsuda H. Testosterone 5alpha-reductase inhibitory active constituents of Piper nigrum leaf. Biol Pharm Bull 2007; 30(12):2402-2405.
• 12. Murugusundram S. Serenoa Repens: Does it have any role in the management of androgenetic alopecia? J Cutan Aesthet Surg 2009; 2(1):31–32.
• 13. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002; 8(2):143-152.
• 14. Rho SS, Park SJ, Hwang SL Lee MH, Kim CD, Lee IH et al. The hair growth promoting effect of Asiasari radix extract and its molecular regulation. J Dermatol Sci 2005; 38(2):89-97.
• 15. Sakaguchi I, Ishimoto H, Matsuo M, Ikeda N, Minamino M, Kato Y. The water-soluble extract of Illicium anisatum stimulates mouse vibrissae follicles in organ culture. Exp Dermatol 2004; 13(8):499-504.
• 16. Datta K, Singh AT, Mukherjee A, Bhat B, Ramesh B, Burman AC. Eclipta alba extract with potential for hair growth promoting activity. J Ethnopharmacol 2009; 124(3):450-456.
• 17. Adhirajan N, Ravi Kumar T, Shanmugasundaram N, Babu M. In vivo and in vitro evaluation of hair growth potential of Hibiscus rosa-sinensis Linn. J Ethnopharmacol 2003; 88(2-3):235-239.
• 18. Matsuda H, Yamazaki M, Asanuma Y, Kubo M. Promotion of hair growth by Ginseng radix on cultured mouse vibrissal hair follicles. Phytother Res 2003; 17(7):797-800.
• 19. Murata K, Takeshita F, Samukawa K, Tani T, Matsuda H. Effects of ginseng rhizome and ginsenoside Ro on testosterone 5α-reductase and hair re-growth in testosterone-treated mice. Phytother Res 2012; 26(1):48-53.
• 20. Murata K, Noguchi K, Kondo M, Onishi M, Watanabe N, Okamura K et al. Inhibitory activities of Puerariae flos against testosterone 5α-reductase and its hair growth promotion activities. J Nat Med 2012; 66: 158-165.
• 21. Kang JI, Kim SC, Kim MK, Boo HJ, Jeon YJ, Koh YS et al. Effect of Dieckol, a Component of Ecklonia cava, on the Promotion of Hair Growth. Int J Mol Sci 2012; 13(5): 6407-23.
• 22. Kang JI, Kim EJ, Kim MK, Jeon YJ, Kang SM, Koh YS et al. The promoting effect of Ishige sinicola on hair growth. Mar Drugs. 2013; 24;11(6):1783-99.
• 23. Borowiecka J., Sienna M.: [Cosmetic use of Rosmarinus officinalis] Wykorzystanie rozmarynu lekarskiego w kosmetyce. Pol J Cosm 2005; 8(3): 183-190.
• 24. Murata K, Noguchi K, Kondo M, Onishi M, Watanabe N, Okamura K et al. Promotion of hair growth by Rosmarinus officinalis leaf extract. Phytother Res 2013; 27(2): 212-7.

Identyfikatory

DOI

10.2478/hepo-2014-0005