Increased AST/ALT ratio in azotaemic dogs infected with Babesia canis

• Autorzy: Zygner W. , Gojska-Zygner O. , Norbury L. J. , Wedrychowicz H.
• Języki publikacji: EN

Abstrakty

EN

The AST/ALT ratio was estimated in 182 dogs infected with Babesia canis. Among these dogs 65 had anaemia and 68 were azotaemic. Student’s t test was used to compare means of the AST/ALT ratio in anaemic and non-anaemic dogs, and in azotaemic and non-azotaemic dogs (p < 0.05). The differences in AST/ALT ratio between anaemic (1.52 ± 1.15) and non-anaemic (1.76 ± 1.34) dogs were statistically insignificant (p = 0.23), however, the comparison of AST/ALT ratio between azotaemic (2.68 ± 1.52) and non-azotaemic (1.08 ± 0.53) dogs revealed a significantly higher value of this index in azotaemic dogs (p = 0.00). The present results suggest that kidney injury contributed to increased AST activity in these dogs.

Słowa kluczowe

EN

dog; animal disease; infection; Babesia canis; azotemia; canine babesiosis; babesiosis; kidney injury; protozoan parasite

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2012
• Tom: 15
• Numer: 3
• Opis fizyczny: p.483-486,fig.,ref.

Twórcy

autor

Zygner W.

• Division of Parasitology and Parasitic Diseases, Department of Preclinical Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences – SGGW, Ciszewskiego 8, 02-786 Warsaw, Poland

autor

Gojska-Zygner O.

autor

Norbury L. J.

autor

Wedrychowicz H.

Bibliografia

• Abramowicz B (2008) Contribution of haemolysis to kidney and liver disturbances in dogs with babesiosis. Med Weter 64: 213-218.
• Adaszek L, Winiarczyk S (2008) Molecular characterization of Babesia canis canis isolates from naturally infected dogs in Poland. Vet Parasitol 152: 235-241.
• De Scally MP, Lobetti RG, Reyers F, Humphris D (2004) Are urea and creatinine values reliable indicators of azotaemia in canine babesiosis? J S Afr Vet Assoc 75: 121-124.
• Furlanello T, Fiorio F, Caldin M, Lubas G, Solano-Gallego L (2005) Clinicopathological findings in naturally occurring cases of babesiosis caused by large form Babesia from dogs of northeastern Italy. Vet Parasitol 134: 77-85.
• Irwin PJ (2009) Canine babesiosis: from molecular taxonomy to control. Parasit Vectors 2: S4.
• Jacobson LS (2006) The South African form of severe and complicated canine babesiosis: Clinical advances 1994-2004. Vet Parasitol 138: 126-139.
• Jurado R, Mattix H (1998) The decreased serum urea nitrogen-creatinine ratio. Arch Intern Med 158: 2509-2511.
• Kjemtrup AM, Wainwright K, Miller M, Penzhorn BL, Carreno RA (2006) Babesia conradae, sp. Nov., a small canine Babesia identified in California. Vet Parasitol 138: 103-111.
• Máthé Á, Dobos-Kovács M, Vörös K (2007) Histological and ultrastructural studies of renal lesions in Babesia canis infected dogs treated with imidocarb. Acta Vet Hung 55: 511-523.
• Máthé Á, Vörös K, Papp L, Reiczigel J (2006) Clinical manifestations of canine babesiosis in Hungary (63 cases). Acta Vet Hung 54: 367-385.
• Welc-Falęciak R, Rodo A, Siński E, Bajer A (2009) Babesia canis and other tick-borne infections in dogs in Central Poland. Vet Parasitol 166: 191-198.
• Zygner W, Gójska-Zygner O, Długosz E, Wędrychowicz H (2011) Liver enzyme activity in dogs infected with Babesia canis. Bull Vet Inst Pulawy 55: 423-427.
• Zygner W, Gójska O, Rapacka G, Jaros D, Wędrychowicz H (2007a) Hematological changes during the course of canine babesiosis caused by large Babesia in domestic dogs in Warsaw (Poland). Vet Parasitol 145: 146-151.
• Zygner W, Górski P, Wędrychowicz H (2009) Detection of the DNA of Borrelia afzelii, Anaplasma phagocytophilum and Babesia canis in blood samples from dogs in Warsaw. Vet Rec 164: 465-467.
• Zygner W, Jaros S, Wędrychowicz H (2008) Prevalence of Babesia canis, Borrelia afzelii, and Anaplasma phagocytophilum infection in hard ticks removed from dogs in Warsaw (central Poland). Vet Parasitol 153: 139-142.
• Zygner W, Rapacka G, Gójska-Zygner O, Długosz E, Wędrychowicz H (2007b) Biochemical abnormalities observed in serum of dogs infected with large Babesia in Warsaw (Poland). Pol J Vet Sci 10: 245-253.