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2013 | 16 | 4 |

Tytuł artykułu

Levels of antioxidant substances, acute phase response and lipid peroxidation in the left and right abomasum displacement in cows

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The aim of the present study was to assess metabolic changes occurring in Holstein cows with left or right abomasal displacement. Total sialic acid (TSA) values of the left abomasal displacement (LDA) group were elevated significantly (p<0.0001) as compared to the controls. In the LDA group, serum ceruloplasmin (CPN) and aspartate transaminase (AST) levels were increased significantly (p<0.0001) as well. Compared to the control group, serum glutathione (GSH) level was decreased significantly in both LDA and right abomasal displacement (RDA) groups (p<0.0001). Among the clinical examination parameters, rumen contraction rates were decreased in both LDA and RDA groups significantly (p<0.0001). These results suggest that inflammatory and oxidative parameters might have taken part in the pathogenesis of abomasal displacement. In this regard, anti-cytokine and anti-oxidant therapies developed in human medicine may also play a potential therapeutic role in the fatty liver and abomasal displacement in cattle.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

16

Numer

4

Opis fizyczny

p.731-733,fig.,ref.

Twórcy

autor
  • Department of Internal Medicine, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University, 15030 Burdur, Turkey
autor
  • Department of Biochemistry, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University, 15030 Burdur, Turkey
autor
  • Department of Biochemistry, Faculty of Veterinary Medicine, Balikesir University, 10100 Balikesir, Turkey
autor
  • Department of Internal Medicine, Faculty of Veterinary Medicine, Balikesir University, 10100 Balikesir, Turkey
autor
  • Department of Internal Medicine, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University, 15030 Burdur, Turkey

Bibliografia

  • Al-Qudah KM, Ismail ZB (2012) The relationship between serum biotin and oxidant/antioxidant activities in bovine lameness. Res Vet Sci 92: 138-141.
  • Devrim AK, Sözmen M, Yiğitarslan K, Sudağidan M, Kankavi O, Atabay HI (2012) Assessment of TNF-α and leptin gene expression by RT-PCR in blood of cows with left abomasal displacement. Rev Med Vet 7: 368-372.
  • Firuzi O, Miri R, Tavakkoli M, Saso L (2011) Antioxidant therapy: current status and future prospects. Curr Med Chem 18: 3871-3888.
  • Geishauser T (1995) Abomasal displacement in the bovine – a review on character, occurrence, aetiology and pathogenesis. Zentralbl Veterinarmed A 42: 229-251.
  • Hasanpour A, Saranjam N, Amuoghli Tabrizi B (2011) Antioxidant concentration status in the serum of cows with left displacement abomasom. Global Veterinaria 7: 478-481.
  • Hull BL, Wass WM (1973) Abomasal displacement. 2. Hypocalcaemia as a contributing causal factor. Vet Med Small Anim Clin 68: 412-417.
  • Mohan SK, Priyav V (2010) Serum total sialic acid, lipid peroxidation, and glutathione reductase levels in patients with rheumatoid arthritis. Turk J Med Sci 40: 537-540.
  • O’Dell JR (1999) Anticytokine therapy – a new era in the treatment of rheumatoid arthritis? N Engl J Med 340: 310-312.
  • Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95: 351-358.
  • Pönniö M, Alho H, Nikkari ST, Olsson U, Rydberg U, Sillanaukee P (1999) Serum sialic acid in a random sample of the general population. Clin Chem 45: 1842-1849.
  • Rahman I, MacNee W (2000) Oxidative stress and regulation of glutathione in lung inflammation. Eur Respir J 16: 534-554.
  • Sillanaukee P, Pönniö M, Jääskeläinen IP (1999) Occurrence of sialic acids in healthy humans and different disorders. Eur J Clin Invest 29: 413-425.
  • Zadnik T (2003) A comparative study of the hemato-biochemical parameters between clinically healthy cows and cows with displacement of the abomasum. Acta Vet-Beograd 53: 297-309.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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