Effect of sprint interval exercises on peripheral level of neuroprotective proteins and human cognitive abilities

• Autorzy: Kujach S. , Olek R. , Kubiak R. , Chroboczek M. , Majkutewicz I. , Laskowski R.
• Języki publikacji: EN

Abstrakty

EN

INTRODUCTION: Overwhelming amount of scientific evidence suggest that regular physical activity is effective in the prevention of chronic diseases. Most adults do not meet even the minimum guidelines for regular physical efforts. Numerous studies have shown that the main reason for the absence of regular exercise is lack of time. Interval training is a potent, time‑efficient therapeutic intervention that is more effective than continuous exercise. Certain evidence indicates that Sprint Interval Exercises (SIE) may result in rapid phenotypic changes in both the cardiovascular system and in the skeletal muscle. However, studies evaluating the effects of SIE on cognitive functions are limited. AIM(S): The aim of this study was to investigate whether SIE affects the peripheral level of selected neuroprotective proteins (BDNF, IGF-1, VEGF) as well as modulate human cognition. METHOD(S): The study involved Gdansk University of Physical Education and Sport students. Subjects were divided in two groups: Sprint Interval Exercise and Control group. To evaluate serum concentrations of BDNF, IGF-1 and VEGF the ELISA method was applied. Cognitive testing include: Stroop interference test, Adult Intelligence Scale Wechsler WAIS-R – Repeat numbers subtest and Trail Making Test part A and B. RESULTS: SIE contributed to a significant, transient increase of three neurotrophins BDNF, IGF-1, VEGF. Obtained results of cognitive functions indicated that acute SIE significantly improved selected human cognitive abilities performance. CONCLUSIONS: The results indicate that proposed SIE can induce positive changes in neuroprotective proteins improving human cognition. Given the growing number of people with cognitive impairment around the world, there is a recognized need for further research, explaining how specific exercise can influence the improvement of these functions. Such studies can be viewed as another important step towards the development of non-pharmacological therapeutic strategies in improving human cognitive function. FINANCIAL SUPPORT: This work was supported by the Polish National Science Center under Grant No: 2012/07/N/ NZ7/01902.

• Wydawca: -
• Czasopismo: Acta Neurobiologiae Experimentalis
• Rocznik: 2017
• Tom: 77
• Numer: Suppl.1
• Opis fizyczny: p.126-127

Twórcy

autor

Kujach S.

• Faculty of Physical Education, Department of Physiology, Gdansk University of Physical Education and Sport, Gdansk, Poland
• Department of Animal and Human Physiology, University of Gdansk, Faculty of Biology, Gdansk, Poland

autor

Olek R.

• Faculty of Kinesiology and Rehabilitation, Department of Bioenergetics and Nutrition, Gdansk University of Physical Education and Sport, Gdansk, Poland

autor

Kubiak R.

• Faculty of Physical Education, Department of Physiology, Gdansk University of Physical Education and Sport, Gdansk, Poland

autor

Chroboczek M.

• Faculty of Physical Education, Department of Physiology, Gdansk University of Physical Education and Sport, Gdansk, Poland

autor

Majkutewicz I.

• Department of Animal and Human Physiology, University of Gdansk, Faculty of Biology, Gdansk, Poland

autor

Laskowski R.

• Faculty of Physical Education, Department of Physiology, Gdansk University of Physical Education and Sport, Gdansk, Poland