EN
Professor Mirosław Mossakowski, was a leading fi gure in neuropathology and neuroscience in Poland. For more than three decades he remained active in the study of various neurological disorders. Foremost was his brilliant early work on the morphological changes of neural cells exposed to ammonia, copper and sera from patients with hepatic encephalopathy, highlighting the critical role of astrocytes in the mechanism of this disorder. The biology and pathology of glial cells studied from the morphological and biochemical points of view, the observation of primary fi brillary gliosis, were particularly innovative. His studies of neurodegenerative diseases brought the opportunity to observe and published fi rst the description of the coexistence of lipid storage diseases and leucodystrophies. His work on cerebral ischemia brought about one of the fi rst demonstrations of imbalance between glycogen synthesis and metabolism in the CNS. In addition to his considerable scientifi c contributions, he extended his inexhaustible energy and untiring devotion to the promotion of neuroscience and neuropathology. Professor Mossakowski served for two terms as a vice-president of the International Society of Neuropathology and on the editorial boards of many journals. He received many prestigious awards and nominations. Professor Mossakowski was a kind and generous man, a superb teacher, and role model. He will be sorely missed by all who were fortunate to experience his matchless wit, knowledge and wisdom.