Classification, structure and molecular diagnostics of avian hepatitis E virus

• Autorzy: Nerc J. , Szeleszczuk P.
• Języki publikacji: EN

Abstrakty

EN

Pathological syndromes caused by avian hepatitis E virus have been described as big liver and spleen disease; necrotic haemorrhagic hepatitis-splenomegaly syndrome; necrotic, haemorrhagic, hepatomegalic hepatitis; or hepatitis-liver haemorrhage syndrome. The aetiological factor of this syndrome belongs to the Hepeviridae family. Avian hepatitis E virus is a single-strand RNA virus whose genome consists of approx. 7,200 base pairs and contains a short non-coding 5’ terminus (27-35 nucleotides) followed by three partially overlapping open reading frames: ORF1, ORF3 and ORF2. Since the avian strains of hepatitis viruses do not replicate in cell cultures, molecular biology techniques are used in the diagnosis of infections. This article discusses in detail the structure and function of each ORF of avian hepatitis E virus, as well as methods for the identification of the genetic material of this pathogen.

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2019
• Tom: 75
• Numer: 09
• Opis fizyczny: p.534-538, fig.,ref.

Twórcy

autor

Nerc J.

• Division of Avian Diseases, Department of Pathology and Veterinary Diagnostics, Faculty of Veterinary Medicine, Warsaw University of Life Sciences - SGGW, Nowoursynowska 159, 02-776 Warsaw, Poland

autor

Szeleszczuk P.

• Division of Avian Diseases, Department of Pathology and Veterinary Diagnostics, Faculty of Veterinary Medicine, Warsaw University of Life Sciences - SGGW, Nowoursynowska 159, 02-776 Warsaw, Poland

Bibliografia

• Agunos A. C., Yoo D., Youssef S. A., Ran D., Binnington B., Hunter D. B.: Avian hepatitis E virus in an outbreak of hepatitis-splenomegaly syndrome and fatty liver haemorrhage syndrome in two flaxseed-fed layer flocks in Ontario. Avian Pathol. 2006, 35, 404-412.
• Ahmad I., Holla P. R., Jameel S.: Molecular virology of hepatitis E virus. Virus Res. 2011, 161, 47-58.
• Berke T., Matson D. O.: Reclassification of the Caliciviridae into distinct genera and exclusion of hepatitis E virus from the family on the basis of comparative phylogenetic analysis. Arch. Virol. 2000, 145, 1421-1436.
• Bilic I., Jaskulska B., Basic A., Morrow C. J., Hess M.: Sequence analysis and comparison of avian hepatitis E viruses from Australia and Europe indicate the existence of different genotypes. J. Gen. Virol. 2009, 90, 863-873.
• Billam P., Huang F. F., Sun Z. F., Pierson F. W., Duncan R. B., Elvinger F., Guenette D. K., Toth T. E., Meng X. J.: Systematic Pathogenesis and Replication of Avian Hepatitis E virus in Specific-Pathogen-Free Adult Chickens. J. Virol. 2005, 79, 3429-3437.
• Billam P., LeRoith T., Pudupakam R. S., Pierson F. W., Duncan R. B., Meng X. J.: Comparative pathogenesis in specific-pathogen-free chickens of two strains of avian hepatitis E virus recovered from a chicken with Hepatitis-Splenomegaly syndrome and from a clinically healthy chicken. Vet. Microbiol. 2009, 139, 253-261.
• Billam P., Sun Z. F., Meng X. J.: Analysis of the complete sequence of an apparently avirulent strain of avian hepatitis E virus (avian HEV) identified major genetic differences compared with the prototype pathogenic strain of avian HEV. J. Gen. Virol. 2007, 88, 1538-1544.
• Gerber P. F., Trampel D. W., Opriessing T.: Identification and characterization of avian hepatitis E virus in 2013 outbreaks of hepatitis-splenomegaly syndrome in two US layer operations. Avian Pathol. 2014, 43, 357-363.
• Haqshenas G., Shivaprasad H. L., Woolcock P. R., Read D. H., Meng X. J.: Genetic identification and characterization of a novel virus related to human hepatitis E virus from chickens with hepatitis-splenomegaly syndrome in the United States. J. Gen. Virol. 2001, 82, 2449-2462.
• Hsu J. W. Y., Tsai H. J.: Avian hepatitis E virus in chickens, Taiwan, 2013. Emerg. Infect. Dis. 2014, 20, 149-151.
• Huang F. F., Haqshenas G., Shivaprasad H. L., Guenette D. K., Woolcock P. R., Larsen C. T., Pierson F. W., Elvinger F., Toth T. E., Memg X. J.: Heterogeneity and Seroprevalance of a Newly Identified Avian Hepatitis E Virus from Chicken in the United States. J. Clin. Microbiol. 2002, 40, 4197-4202.
• Huang F. F., Sun Z. F., Emerson S. U., Purcell R. H., Shivaprasad H. L., Pierson F. W., Toth T. E., Meng X. J.: Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV. J. Gen. Virol. 2004, 85, 1609-1618.
• Irza V., Sprygin A.: Hepatitis splenomegay syndrome, a newly identified hen viral disease in Russia. J. Agric. Biol. 2012, 4, 73-77.
• Johne R., Dremsek P., Reetz J., Heckel G., Hess M., Ulrich R. G.: Hepeviridae: An expanding family of vertebrate viruses. Infect. Genet. Evol. 2014, 27, 212-229.
• Kwon H. M., Sung H. W., Meng X. J.: Serological prevalence, genetic identification, and characterization of the first strains of avian hepatitis E virus from chickens in Korea. Virus Genes 2012, 45, 237-245.
• Li H., Zhu R., She R., Zhang C., Shi R., Li W., Du F., Wu Q., Hu F., Zhang Y., Soomro M. H., Zheng C.: Case report associated with aspergillosis and hepatitis E virus coinfection in Himalayan griffons. BioMed Res. Int. 2015.
• Lin J., Norder H., Uhlhorn H., Belak S., Widen F.: Novel hepatitis E like virus in Swedish moose. J. Gen. Virol. 2014, 95, 557-570.
• Marek A., Bilic I., Prokofieva I., Hess M.: Phylogenetic analysis of avian hepatitis E virus samples from European and Australian chicken flocks supports the existence of a different genus within the Hepeviridae comprising at least three different genotypes. Vet. Microbiol. 2010, 145, 54-61.
• Meng X. J.: Hepatitis E virus: Animal reservoirs and zoonotic risk. Vet. Microbiol. 2010, 140, 256-265.
• Meng X. J.: Recent advances in Hepatitis E Virus. J. Viral Hepatitis 2010, 17, 153-161.
• Meng X. J., Anderson D. A., Arankalle V. A., Emerson S. U., Harrison T. J., Jameel S., Okamoto H.: Create two new genera, Orthohepevirus and Avihepevirus, and remove the current sole genus Hepevirus in the family Hepeviridae. Taxonomic proposal to the ICTV Executive Committee 2010.
• Payne C. J., Ellis T. M., Plant S. L., Gregory A. R., Wilcox G. E.: Sequence data suggesting big liver and spleen disease virus (BLSV) is genetically related to hepatitis E virus. Vet. Microbiol. 1999, 68, 119-125.
• Peralta B., Biarnes M., Ordonez G., Porta R., Martin M., Mateu E., Pina S., Meng X. J.: Evidence of widespread infection of avian hepatitis E virus (avian HEV) in chicken from Spain. Vet. Microbiol. 2009, 137, 31-36.
• Reuter G., Boros A., Matics R., Kapusinszky B., Delwart E., Pankovics P.: A novel avian-like hepatitis E virus in wild aquatic bird, little egret (Egretta garzetta), in Hungary. Infection, Genetics & Evolution 2016, 46, 74-77.
• Reuter G., Boros A., Matics R., Kapusinszky B., Delwart E., Pankovics P.: Divergent hepatitis E virus in birds of prey, common kestrel (Falco tinnunculus) and red-footed falcon (F. vespertinus), Hungary. Infection, Genetics & Evolution 2016, 43, 343-346.
• Smith D. B., Simmonds P., Jameel S., Emerson S. U., Harrison T. J., Meng X. J., Okamoto H., Van der Poel W. H. M., Purdy M. A.: Consensus proposals for classification of the family Hepeviridae. J. Gen. Virol. 2014, 95, 2223-2232.
• Sprygin A. V., Nikonova Z. B., Zinyakov N. G.: Avian hepatitis E virus identified in Russian chicken flocks exhibits high genetic divergence based on the ORF2 capsid gene. Avian Pathol. 2012, 41, 459-463.
• Sun Z. F., Larsen C. T., Dunlop A., Huang F. F., Pierson F. W., Toth T. E., Meng X. J.: Genetic identification of avian hepatitis E virus (HEV) from healthy chicken flocks and characterization of the capsid gene of 14 avian HEV isolates from chickens with hepatitis – splenomegaly syndrome in different geographical regions of the Unites States. J. Gen. Virol. 2004, 85, 693-700.
• Sun Z. F., Larsen C. T., Huang F. F., Billam P., Pierson F. W., Toth T. E., Meng X. J.: Generation and infectivity titration of an infectious stock of avian hepatitis E virus (HEV) in chickens an cross-species infection of turkeys with avian HEV. J. Clin. Microbiol. 2004, 42, 2658-2662.
• Syed S. F., Sun Y., Du T., Chen Y., Liu B., Wang X., Li H., Nan Y., Zhou E-M., Zhao Q.: Evaluation of recombinant Chinese avian hepatitis E virus (CaHEV) ORF2 and ORF3 proteins for protection of chickens against CaHEV infection. Vaccine 2017, 35, 3482-3489.
• Szeleszczuk P., Żbikowski A., Dolka I., Gawlik P., Szewczyk R., Mieszczyński T.: Zakażenia wirusem zapalenia wątroby typu E u drobiu. Mat. I Kongresu Praktyki Weterynaryjnej. Łódź 2011, 153-156.
• Troxler S., Marek A., Prokofieva I., Bilic I., Hess M.: TaqMan Real-Time Reverse Transcription-PCR Assay for Universal Detection and Quantification of Avian Hepatitis E Virus from Clinical Samples in the Presence of a Heterologous Internal Control RNA. J. Clin. Microbiol. 2011, 49, 1339-1346.
• Troxler S., Pać K., Prokofieva I., Liebhart D., Chodakowska B., Furmanek D., Hess M.: Subclinical circulation of avian hepatitis E virus within a multiple-age rearing and broiler breeder farm indicates persistence and vertical transmission of the virus. Avian Pathol. 2014, 43, 310-318.
• Vasickova P., Psikal I., Kralik P., Widen., Hubalek., Pavlik I.: Hepatitis E virus: a review. Vet. Med. (Praha) 2007, 52, 365-384.
• Woo P. C. Y., Lau S. K. P., Teng J. L. L., Tsang A. K. L., Joseph M., Wong E. Y. M., Tang Y., Sivakumar S., Xie J., Bai R., Wernery R., Wernery U., Yuen K. Y.: New hepatitis E virus genotype in camels, the Middle East. Emerg. Infect. Dis. 2014, 20, 1044-1048.
• World Health Organization: Hepatitis E vaccine: WHO position paper, May 2015. Weekly Epidemiol. Rec. 2015, 90, 185-200.
• Zhang X., Bilic I., Troxler S., Hess M.: Evidence of genotypes 1 and 3 of avian hepatitis E virus in wild birds. Virus Res. 2017, 228, 75-78.
• Zhao Q., Liu B., Sun Y., Du T., Chen Y., Wang X., Li H., Nan Y., Zhang G., Zhou E. M.: Decreased egg production in laying hens associated with infection with genotype 3 avian hepatitis E virus strain from China. Vet. Microbiol. 2017, 203, 174-180.
• Zhao Q., Xie S., Sun Y., Chen Y., Gao J., Li H., Wang X., Syed S. F., Liu B., Wang L., Zhang G., Zhou E. M.: Development and evaluation of a SYBR Green real-time RT-PCR assay for detection of avian hepatitis E virus. BMC Veterinary Research 2015, 11:195. Doi:10.1186/s12917-015-0507-5
• Zhao Q., Zhou E. M., Dong S. W., Qiu H. K., Zhang L., Hu S. B., Zhao F. F., Jiang S. J., Sun Y. N.: Analysis of Avian Hepatitis E Virus from Chickens, China. Emerg. Infect. Dis. 2010, 16, 1469-1472.

Identyfikatory

DOI

10.21521/mw.6228