Metabolic response to starvation in late pregnant rats. I. Maternal response

• Autorzy: Nowacka M. , Gorski J.
• Języki publikacji: EN

Abstrakty

EN

Nowacka, M. and. Górski, J.: Metabolic response to starvation dn late pregnant rats. I. Maternal response. Acta physiol, tpoi. 1988, 39(5-6): 427-434. The aim of the present study was to examine effect of prolonged fasting on muscle glycogen and triglyceride concentration as well as on non-protein nitrogen excretion with urine in late pregnant rats. They were divided into four groups: I - fed, pregnant for 21 days, II-fasted for one day (from 20 to 21 day of pregnancy), III-fasted for two days (from 19 to 21 day) and IV-fasted for three days (from 18 to 21 day). The concentration of glycogen and triglycerides was determined in the following tissues: the white and red layers of the vastus lateralis, the soleus, the diaphragm, the heart and the liver. The urine was collected-in each group 24 h (from 20 to 21 day). It has been found that concentration of glycogen in the leg muscles is reduced by about 50% and in the diaphragm by 75% already after 24h fasting and then remains stable. The concentration of glycogen in the heart increases after one day of fasting and then returns to the control value. The effect of fasting on the concentration of triglycerides in the tissues depends on a tissue- studied. It decreases gradually in the white vastus, .and in the soleus only on the third, day. It is elevated during the first two days of fasting in the red vastus, diaphragm and liver and returns to the control level on the thrid day. The fasting doubled the concentration of triglycerides in the heart. The urinary urea, creatinine, and uric acid excretion decreases and ammonia excretion increases during fasting. The results obtained indicate that the late gestation does not alter response of muscle glycogen metabolism to fasting as compared to the male rats. It does effect metabolism of triglycerides.

• Wydawca: -
• Czasopismo: Acta Physiologica Polonica
• Rocznik: 1988
• Tom: 39
• Numer: 5-6
• Opis fizyczny: p.427-434,ref.

Twórcy

autor

Nowacka M.

• Department of Clinical Physiology and Department of Physiology, School of Medicine, Bialystok, Poland

autor

Gorski J.

• Department of Clinical Physiology and Department of Physiology, School of Medicine, Bialystok, Poland

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