Qualitative and quantitative characteristics of selected bacterial groups in children with inflammatory bowel diseases

• Autorzy: Roszak D. , Galecka M. , Cichy W. , Szachta P.
• Języki publikacji: EN

Abstrakty

EN

The aim of the study was evaluation of qualitative and quantitative changes in bacterial ecosystem in 109 children with inflammatory bowel diseases. Stools obtained from patients were analysed for selected bacteria and concentration of faecal inflammatory markers (calprotectin, lactoferrin, M2-PK). The number of selected microorganisms depends on the level of clinical activity of disease and is correlated with faecal concentration of inflammatory markers. Differences in microflora disturbance, observed in patients with Crohn’s disease and ulcerative colitis, may suggest different causes of development of both pathologies.

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2016
• Tom: 65
• Numer: 2
• Opis fizyczny: p.219-224,ref.

Twórcy

autor

Roszak D.

• First Department of Pediatrics; Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland

autor

Galecka M.

• Institute of Microecology, Poznan, Poland

autor

Cichy W.

• First Department of Pediatrics; Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland

autor

Szachta P.

• Institute of Microecology, Poznan, Poland

Bibliografia

• Andoh A. and J. Fujiyama. 2006. Therapeutic approaches targeting intestinal microflora in inflammatory bowel disease. World J. Gastroenterol. 12: 4452–4460.
• Austin G.L., H.H. Herfarth and R.S. Sandler. 2007. A critical evaluation of serologic markers for inflammatory bowel disease. Clin. Gastroenterol. Hepatol. 5(5): 545–547.
• D’Haens G., K. Geboes, M. Peeters , F. Baert, F. Penninckx andP. Rutgeerts. 1998. Early lesions of reccurent Crohn’s disease caused by infusion of intestinal contents in excluded ileum. Gastroenterol. 114: 262–267.
• Gałecka M., P. Szachta, A. Bartnicka, L. Łykowska-Szuber, P. Eder and A. Schwiertz. 2013. Faecalibacterium prausnitzii and Crohn’s disease – is there any connection? Pol. J. Microbiol. 62(1): 91–95.
• Gerard R., B. Sendid, J.F. Colombel, D. Poulain and T. Jouault. 2015. An immunological link between Candida albicans colonization and Crohn’s disease. Crit. Rev. Microbiol. 41(2): 135–139.
• Gibson G.R. and M.B. Roberfroid. 1995. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics.J. Nutr. 125(6): 1401–1412.
• Kamińska B., P. Landowski and A. Szarszewski. 2004. Assessment of bacterial microflora in large intestine paying special attention to sulphate reducing bacteria in course of nonspecific enteritis in children (in Polish). Scientific materials of the XI Congress of PTG. Warsaw.
• Lakatos P., S. Fischer and L. Lakatos. 2006. Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: Pathogenic bacteria and altered bacterial sensing or changes in mucosal integrity take “toll”? World J. Gastroenterol. 12: 1829–1841.
• Maukonen J., K.L. Kolho, M. Paasela, J. Honkanen, P. Klemetti, O. Vaarala and M. Saarela. 2015. Altered fecal microbiota in paediatric inflammatory bowel disease. J. Crohns Colitis. 9(12): 1088–1095.
• Monaghan T.M., A. Cockayne and Y.R. Mahida. 2015. Pathogenesis of Clostridium difficile infection and its potential role in inflammatory bowel disease. Inflamm. Bowel Dis. 21(8): 1957–1966.
• Rosińska A., I. Grzeszczak, A. Zawirska, H. Kubisiak-Rzepczyk, Z. Adamski, N. Kobelska-Dubiel and W. Cichy. 2007. Infections by Candida (yeasts-similar) in children suffering from nonspecific enteritis (in Polish). Pediatr Pol. 82(3): 220–226.
• Ryzko J. and M. Woynarowski. 1995. Assessment of nonspecific enteritis course in children according to scoring system (in Polish). Pediatr Pol. 70: 569–573.
• Sellon R.K., S. Tonkonogy, M. Schultz, L.A. Dieleman, W. Grenther, E. Balish, D.M. Rennick and R.B. Sartor. 1998. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun. 66: 5224–5231.
• Wank Z.K., Y. Yang, Y. Chen, J. Yuan, G. Sun and L.H. Peng. 2014. Intestinal microbiota pathogenesis and fecal microbiota transplantation for inflammatory bowel disease. World J. Gastroenterol. 20(40): 14805–14820.
• Zwolińska-Wcisło M., A. Budak, D. Trojanowska, J. Bogdał and J. Stachura. 2004. Study of Candida sp. influence on the course of large intestine ulcerous enteritis (in Polish). Scientific materialsof the XI Congress of PTG. Warsaw.

Identyfikatory

DOI

10.5604/17331331.1204483