Bovine mammary stem cells studies – current status – a review*

• Autorzy: Bierla J.B , Osinska E. , Motyl T.
• Języki publikacji: EN

Abstrakty

EN

Bovine mammary gland is a unique organ with regard to its frequently repeating cycles of growth and involution throughout the life of an animal. In literature there is only scarce information concerning development of its specific epithelium and in particular about the stem and progenitor cells. Knowledge about this subject is essential in terms of further improvement of dairy cows production capacity in the future. It may also provide an answer to the question concerning the lack of carcinogenesic transformation in bovine mammary gland, as frequency of tumours in this tissue equals zero. The morphological features of human mammary gland are more similar to those in cattle than in rodents, commonly used for carcinogenetic studies. The results obtained on the bovine model may also constitute a basis for understanding fundamentals of carcinogenesis in human mammary gland.To confirm the presence of mammary stem cells, many in vitro and in vivo studies were conducted with the use of transplantation, electron microscopy, functional techniques, flow cytometry, scanning cytometry and microarrays. Unfortunately, until now no universal molecular marker was found which could make it easier to identify these cells. It has been suggested that the population of cells Sca-1pos CD45neg, for which the lack of steroid receptors is characteristic, may indicate the stem cell population. In our current studies it was found that in the mammary gland tissue, parallel to Sca-1pos CD45neg cells, a population of Sca-1pos CD45pos cells exists which might be of hematopoietic origin.This non-epithelial lineage may enrich the stem/progenitor cell population in the mammary gland facilitating mammary gland renewal.

• Wydawca: -
• Czasopismo: Animal Science Papers and Reports
• Rocznik: 2012
• Tom: 30
• Numer: 3
• Opis fizyczny: p.195-204,ref.

Twórcy

autor

Bierla J.B

• Department of Physiology and Pathophysiology, Faculty of Pharmacy, Medical University of Warsaw, Pawinskiego 3C, 02-106 Warsaw, Poland

autor

Osinska E.

autor

Motyl T.

Bibliografia

• AKERS R.M., 1990 – Lactation physiology: a ruminant animal perspective. Protoplasma 159, 96-111.
• ALISON M.R., POULSOM R., JEFFERY R., DHILLON A.P., QUAGLIA A., JACOB J.,NOVELLI M., PRENTICE G., WILLIAMSON J., WRIGHT N.A., 2000 – Hepatocytes from nonhepatic adult stem cells. Nature 406(6793), 257.
• ALVI A. J., CLAYTON H., JOSHI C., ENVER T., ASHWORTH A., VIVANCO M.M., DALE T.C.,SMALLEY M.J., 2003 – Functional and molecular characterisation of mammary side population cells. Breast Cancer Research 5, 1-8.
• CAIRNS J., 1975 – Mutation selection and the natural history of cancer. Nature 255, 197-200.
• CAPUCO A.V., LI M., LONG E., REN S., HRUSKA K.S., SCHORR K., FURTH P.A., 2002 –Concurrent pregnancy retards mammary involution: effects on apoptosis and proliferation of the mammary epithelium after forced weaning of mice. Biology of Reproduction 66 (5), 1471-1476.
• CAPUCO A.V., ELLIS S., 2005 – Bovine mammary progenitor cells: current concepts and future directions. Journal of Mammary Gland Biology and Neoplasia 10 (1), 5-15.
• CAPUCO A.V., 2007 – Identification of putative bovine mammary epithelial stem cells by their retention of labeled DNA strands. Experimental Biology and Medicine 232, 1381-1390.
• CAPUCO A.V., EVOCK-CLOVER C.M., MINUTI A.,WOOD D.L., 2009 – In Vivo Expansion of the Mammary Stem/ Progenitor Cell Population by Xanthosine Infusion. Experimental Biology and Medicine 234, 475-482.
• CHEPKO G., SMITH G.H., 1997 – Three division-competent, structurally distinct cell populations contribute to murine mammary epithelial renewal. Tissue and Cell 29, 239-253.
• CHEPKO G., DICKSON R.B., 2003 – Ultrastructure of the putative stem cell niche in rat mammary epithelium. Tissue and Cell 35, 83-93.
• CORBEL S.Y., LEE A., YI L., DUENAS J., BRAZELTON T.R., BLAU H.M., ROSSI F.M., 2003 – Contribution of hematopoietic stem cells to skeletal muscle. Nature Medicine 9(12), 1528-1532.
• COTSARELIS F., SUN T.T., LAVKER R.M., 1990 – Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61, 1329-1337.
• DANIEL C.W., DEOME K.B., YOUNG J.T., BLAIR P.B., FAULKIN L.J. Jr., 1968 – The in vivo life span of normal and preneoplastic mouse mammary glands: a serial transplantation study. Proceedings of the National Academy of Sciences of the USA 61, 53-60.
• DEOME K.B., FAUKLIN L.J., BERN H.A., BLAIR P.B., 1959 – Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice. Journal of the National Cancer Institute 78, 751-757.
• ELLIS S., CAPUCO A.V., 2002 – Cell proliferation in bovine mammary epithelium: identification of the primary proliferative cell population. Tissue and Cell 34(3), 155-163.
• EIREW P., STINGL J, RAOUF A., TURASHVILI G., APARICIO S., EMERMAN J.T., EAVES C.J., 2008 – A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability. Nature Medicine 14, 1384-1389.
• FERGUSON D.J.P., 1985 – Ultrastructural characterization of the proliferative (stem?) cells within the parenchyma of the normal “resting” breast. Virchows Archiv A: Pathology Pathologische Anatomie 407, 379-385.
• GOUON-EVANS V., ROTHENBERG M.E., POLLARD J.W., 2000 – Postnatal mammary gland development requires macrophages and eosinophils. Development 127(11), 2269-2282.
• GOODELL M.A., BROSE K., PARADIS G., CONNER A.S., MULLIGAN R.C., 1996 – Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo . Journal of Experimental Medicine 183, 1797-806.
• HOLLAND M.S., TAI M.H., TROSKO J.E., GRIFFIN L.D., STASKO J.A., CHEVILLE N.C.,HOLLAND R.E., 2003 – Isolation and differentiation of bovine mammary gland progenitor cell populations. American Journal of Veterinary Research 64, 396
• HOVEY R.C., MCFADDEN T.B., AKERS R.M., 1999 – Regulation of mammary gland growth and morphogenesis by the mammary fat pad: a species comparison. Journal of Mammary Gland Biology Neoplasia 4, 53-68.
• JACKSON K.A., MAJKA S.M., WANG H., POCIUS J., HARTLEY C.J., MAJESKY M.W.,ENTMAN M.L., MICHAEL L.H., HIRSCHI K.K., GOODELL M.A., 2001 – Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. Journal of Clinical Investigations 107(11), 1395-1402.
• JIANG S., LEE B.C., FU Y., AVRAHAM S., LIM B., KARSENTY AVRAHAM H., 2010-Reconstitution of mammary epithelial morphogenesis by murine embryonic stem cells undergoing hematopoietic stem cell differentiation. PLoS ONE 5(3): e9707. doi:10.1371/journal.pone.0009707.
• JONKER J.W., FREEMAN J., BOLSCHER E., MUSTERS S., ALVI A. J., TITLEY I., SCHINKEL A.H., DALEB T.C., 2005 – Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland. Stem Cells 23, 1059-1065.
• KORDON E.C., SMITH G.H., 1998 – An entire functional mammary gland may comprise the progeny from a single cell. Development 125, 1921-1930.
• KOLEK S., GAJKOWSKA B., MOTYL T., 2008 – Morphological and molecular markers of stem and progenitor cells in the mammary gland. In Polish, summary in English. Medycyna Wetrynaryjna 64, 136-141.
• LAGASSE E., CONNORS H., AL-DHALIMY M., REITSMA M., DOHSE M., OSBORNE L.,WANG X., FINEGOLD M., WEISSMAN I.L., GROMPE M., 2000 – Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nature Medicine 6(11), 1229-1234.
• LANSDORP P.M., 2007 – Immortal strands? Give me a break. Cell 129, 1244-1247.
• MARTIGNANI E., EIREW P., EAVES C., BARATTA M., 2009 – Functional identification of bovine mammary epithelial stem/progenitor cells. Veterinary Research Communications 33 (1), 101-103.
• MERINO G., REAL R., BARO M.F., GONZALEZ-LOBATO L., PRIETO J.G., ALVAREZ A.I.,MARQUES M.M., 2009 – Natural allelic variants of bovine ABCG2 transporter: Increased activity of the S581 variant and development of tools for the discovery of new ABCG2 inhibitors. Drug Metabolism and Disposition 37(1), 5-9.
• MOTYL T., BIERŁA J.B., KOZŁOWSKI M., GAJEWSKA M., GAJKOWSKA B.,KORONKIEWICZ M., 2011 – Identification, quantification and transcriptional profile of potential stem cells in bovine mammary gland. Livestock Science 136 (2011) 136-149.
• ORLIC D., KAJSTURA J., CHIMENTI S., JAKONIUK I., ANDERSON S.M., LI B., PICKEL J.,MCKAY R., NADAL-GINARD B., BODINE D.M., LERI A., ANVERSA P., 2001 – Bone marrow cells regenerate infarcted myocardium. Nature 410(6829), 701-705
• PATT H.M., MALONEY M.A., LAMELA R.A., 1980 – Hematopoietic stem cell proliferative behavior as revealed by bromodeoxyuridine labeling. Experimental Hematology 8(8), 1075-1079.
• POVEY R.C., OSBORNE, A.D., 1969 – Mammary gland neoplasia in the cow: a review of literature and report of a fibrosarcoma. Veterinary Pathology 6 (1), 502-512.
• RANDO T.A., 2007 – The immortal strand hypothesis: Segregation and reconstruction. Cell 129,1239-1243.
• RAOUF A., ZHAO Y., TO K., STINGL J., DELANEY A., BARBARA M., ISCOVE N., JONES S., MCKINNEY S., EMERMAN J., APARICIO S., MARRA M., EAVES C. 2008 – Transcriptome analysis of the normal human mammary cell commitment and differentiation process. Cell Stem Cell 3, 109-118.
• RATAJCZAK M.Z., ZUBA-SURMA E.K., WYSOCZYNSKI M., RATAJCZAK J., KUCIA M.,2008 – Very small embryonic-like (VSEL) stem cells in adult organs and their potential Experimental Gerontology 36, 742-751.
• SANGAI T., ISHII G., FUJIMOTO H., IKEHARA A., ITO T., HASEBE T., MAGAE J.,NAGASHIMA T., MIYAZAKI M., OCHIAI A., 2006 – Hormonal stimulation increases the recruitment of bone marrow-derived myoepithelial cells and periductal fibroblasts into the mammary gland. Biochemical and Biophysical Research Communications 346(4), 1173-1180.
• SHACKLETON M., VAILLANT F., SIMPSON K.J., STINGL J., SMYTH G.K., ASSELINLABAT M.L., WU L., LINDEMAN G.J., VISVADER J.E., 2006 – Generation of a functional mammary gland from a single cell. Nature 439, 84-88.
• SHIMIZU K., SUGIYAMA S., AIKAWA M., FUKUMOTO Y., RABKIN E., LIBBY P., MITCHELL R.N., 2001 – Host bone-marrow cells are a source of donor intimal smooth- muscle-like cells in murine aortic transplant arteriopathy. Nature Medicine 7(6), 738-741.
• SMITH G.H., MEDINA D., 1988 – A morphologically A morphologically distinct candidate for an epithelial stem cell in mouse mammary gland. Journal of Cell Science 90, 173-183.
• SMITH G.H., 1996 – Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Research and Treatment 39(1), 21-31.
• SLEEMAN K.E., KENDRICK H., ROBERTSON D., ISACKE C.M., ASHWORTH A.,SMALLEY M.J., 2007 – Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. Journal of Cell Biology 176(1), 19-26.
• STINGL J., EAVES C.J., KUUSK U., EMERMAN J.T., 1998 – Phenotypic and functional characterization in vitro of multipotent epithelial cell present in the normal adult human breast.Differentiation 63, 201-213.
• STINGL J., EAVES C.J., ZANDIEH I., EMERMAN J.T., 2001. – Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue. Brest Cancer Research and Treatment 67, 93-109.
• STINGL J., EIREW P., RICKETSON I., SHACKLETON M., VAILLANT F., CHOI D., LI H.I.,EAVES C.J., 2006 – Purification and unique properties of mammary epithelial stem cells. Nature 439, 993-997.
• STINGL J., 2009 – Detection and analysis of mammary gland stem cells. Journal of Pathology 217(2), 229-241.
• SWETT W.W., MATTHEWS C.A., GRAVES R.R., 1940 – Extreme rarity of cancer in the cow’s udder: a negative finding of vital interest to the dairy industry and to the consumer. Journal of Dairy Science 23( 1), 437-446.
• TUCKER H.A., 1979 – Endocrinology of lactation. Seminars in Perinatology 3, 199-223.
• TUMBAR T., GUASCH G., GRECO V., BLANPAIN C., LOWRY W.E., RENDL M., FUCHS E.,2004 – Defining the epithelial stem cell niche in skin. Science 303, 359-363.
• VILLADSEN R., FRIDRIKSDOTTIR A.J., RŘNNOV-JESSEN L., GUDJONSSON T., RANK F.,LABARGE M.A., BISSELL M.J., PETERSEN O.W., 2007 – Evidence for a stem cell hierarchy in the adult human breast. Journal of Cell Biology 177, 87-101.
• WELM B.E., TEPERA S.B., VENEZIA T., GRAUBERT T.A., ROSEN J.M., GOODELL M.A.,2002 – Sca-1 (pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Developmental Biology 245, 42-56.
• ZHANG H., REN C., YANG X., WANG L., LI H., ZHAO M., YANG H., YAO K., 2007 –Identification of label-retaining cells in nasopharyngeal epithelia and nasopharyngeal carcinoma tissue. Histochemistry and Cell Biology 127, 247-354.
• ZHOU S., SCHUETZ J.D., BUNTING K.D., COLAPIETRO A.M., SAMPATH J., MORRIS J.J.,LAGUTINA I., GROSVELD G.C., OSAWA M., NAKAUCHI H., SORRENTINO B.P., 2001 – The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side population phenotype. Nature Medicine 7, 1028-34.
• ZUBA-SURMA E.K., KUCIA M., DAWN B., GUO Y., RATAJCZAK M.Z., BOLLI R., 2008 – Bone marrow-derived pluripotent very small embryonic-like stem cells (VSELs) are mobilized after acute myocardial infarction. Journal of Molecular and Cellular Cardiology 44(5), 865-873.

Uwagi

PL

Rekord w opracowaniu