Characterisation and immunogenic properties of Polish strains of RHD virus

• Autorzy: Fitzner A.
• Języki publikacji: EN

Abstrakty

EN

The new field strains of rabbit haemorrhagic disease virus (RHDV), characterised by different reactivity in ELISA similar to antigenic variant of RHDVa and non-haemagglutinating isolate, are described. The specimens were isolated from small rabbitries from natural outbreaks suspected of rabbit haemorrhagic disease (RHD) and from experimentally-infected animals. RHD was confirmed on the basis of high mortality rate, clinical and necropsy features, and positive results in HA, ELISA, and RT-PCR. The isolates were able to infect unvaccinated rabbits but laboratory animals immunised with a commercial vaccine were fully protected. The immunisation of rabbits with three different inactivated field strains demonstrated the seroconversion and efficacy of the experimental vaccines against challenge with virulent strains of RHDV.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2009
• Tom: 53
• Numer: 4
• Opis fizyczny: p.575-582,fig.,ref.

Twórcy

autor

Fitzner A.

• Department of Foot-and-Mouth Disease, National Veterinary Research Institute, 98-220 Zdunska Wola, Poland

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