Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2012 | 21 | 3 |
Tytuł artykułu

Spectrophotometrically and chemometrically assisted studies on the photostability of terazosyne in an aqueous environment

Warianty tytułu
Języki publikacji
The behavior of terazosine hydrochloride (TR), representative of the selective at-adrenergic blockers in river water under the influence of sunlight, was tested. Details of the photodegradation process were obtained using principal component analysis (PCA) and multivariate curve resolution alternating least squares (MCRALS) chemometric methods and confirmed by HPLC analysis. Additionally, the impact of some factors important for efficient waste treatment were studied. For this purpose a stability of terazosine aqueous solutions under the influence of UV, UV+H₂O₂, Fenton, and photo-Fenton processes and sunlight was studied. The presence of H₂O₂ and Fe (II) ions increases the rate of transformation. The process of direct photolysis and H₂O₂-assisted photoreaction showed first order kinetics, while dark and photo-Fenton reactions exhibited second-order kinetics.
Słowa kluczowe
Opis fizyczny
  • 1. HALLING-SØRENSEN B., NORS NIELSEN S., LANZKY P.F., INGERSLEV F., HOLTEN LÜTZHØFT H.C., JØRGENSEN S.E. Occurrence, fate and effects of pharmaceutical substances in the environment - a review. Chemosphere 36, 357,1998.
  • 2. RICHARDSON S.D. Water analysis: emerging contaminants and current issues. Anal. Chem. 81, 4645, 2009.
  • 3. STAN H.J., HEBERER T. Pharmaceuticals in aquatic environment. Analusis 25, M20,1997.
  • 4. KÜMMERER K. Drugs in the environment: emission of drugs, diagnostic aids and disinfectants into wastewater by hospitals in relation to other sources - a review. Chemosphere 45, 957, 2001.
  • 5. ZUCCATO E., CASTIGLIONI S., BAGNATI R, CHIABRANDO C., GRASSI P., FANELLI R. Illicit drugs, a novel group of environmental contaminants. Water Res. 42, 961, 2008.
  • 6. ELLIS J.B. Pharmaceutical and personal care products (PPCPs) in urban receiving waters. Environ. Pollut. 144, 184, 2006.
  • 7. DORNE J.L.C.M., RAGAS A.M.J., FRAMPTON G.K., SPURGEON D.S., LEWIS D.F. Trends in human risk assessment of pharmaceuticals. Anal. Bioanal. Chem. 387, 1167, 2007.
  • 8. BOREEN A.L., ARNOLD W.A., McNEILL K. Photodegradation of pharmaceuticals in the aquatic environment: A review. Aquat. Sci. 65, 320, 2003.
  • 9. KHETAN S.K, COLLINS T.J. Human pharmaceuticals in the aquatic environment: a challenge to green chemistry. Chem. Rev. 107, 2319, 2007.
  • 10. FARRE M, PEREZ S., KANTIANI L, BARCELO D. Fate and toxicity of emerging pollutants, their metabolites and transformation products in the aquatic environment. Trends Anal. Chem. 27, 991, 2008.
  • 11. HÖFL C, SIGL G, SPECHT O., WURDACK I., WABNER D. Oxidative degradation of OAX and COD different advanced processes: a comparative study with two samples of pharmaceutical wastewater. Water Sci. Technol. 35, 257, 1997.
  • 12. CUNNINGHAM V.L., HUTCHINGSON T., MASTROCCO F, PARKE N, RODEN N. Effects of human pharmaceutical on aquatic life: next steps. Environ. Sei. Technol. 40, 3457, 2006.
  • 13. SCHULMAN L.J., SARGENT E. V., NAUMANN B. D., FARIA E.C., DOLAN D.G., WARGO J.P. A human health risk assessment of pharmaceuticals in the aquatic environment. Hum. Ecol. Risk Assess. 8, 657, 2002.
  • 14. ZEPP R.G, CLINE D. M. Rates of direct photolysis in aquatic environment. Environ. Sci. Technol. 11, 359,1977.
  • 15. ZEPP R.G, SCHLOTZHAUER P.F, SINK R.M. Photosensitized transformations involving electronic energy transfer in natural waters: role of humic substances. Environ. Sci. Technol. 19, 74,1985.
  • 16. ZEPP R.G, HOLGNE J, BADER H. Nitrate-induced photooxidation of trace organic chemicals in water. Environ. Sci. Technol. 21, 443,1987.
  • 17. GÜLTEKIN I, INCE N.H. Synthetic endocrine disruptors in the environment and water remediation by advanced oxidation processes. J. Environ. Manag. 85, 816, 2007.
  • 18. SHARMA V.K. Oxidative transformations of environmental pharmaceuticals by Cl₂, ClO₂, O₃, and Fe(VI): Kinetic assessment. Chemosphere 73, 1379, 2008.
  • 19. CANONICA S, MEUNIER L., VON GUNTEN U. Phototransformation of selected pharmaceuticals during UV treatment of drinking water. Water Res. 42, 121, 2008.
  • 20. GACIONG Z., HRUBY Z, CICHOCKA J, PRZYBYLSKI J. Pharmacology of hypertension. PZWL ed. Warsaw, 1998.
  • 21. DANYSZ A, KLEINROK Z. Basic of pharmacology. Vohimed ed., Wrocław, 1996.
  • 22. PADLEWSKI J.K, CHWALIBOGOWSKA-PADLEWSKA A. Pharmaceuticals in modern therapy. Buchner Foundation ed., Warsaw, 1998.
  • 23. WANG CH.CH., LUCONI M.O., MASI A.N., FERNANDEZ L. Determination of terazosine by cloud point extraetion - fluorimetric combined methodology. Talanta 72, 1779, 2007.
  • 24. OJHA T, BAKSHI M., CHAKRABORTI A.,K., SINGH S. The ICH guidance in practice: stress decomposition studies on three piperazinyl quinzoline adrenergic receptor-blocking agents and comparison of their degradation behaviour. J. Pharm. Biomed. Anal 31, 775, 2003.
  • 25. SZLINDER-RICHERT J., MAZERSKI J., CYBULSKA B., GRZYBOWSKA J., BOROWSKI E. MFAME, N-methyl- N-d-fructosyl amphotericin B methyl ester, a new amphotericin B derivative of low toxicity: relationship between self-association and effects on red blood cells. Biochim. Biophis. Acta 1528, 15,2001.
  • 26. AMIGO J.M., DE JUAN A., COELLO J., MASPOCH S. A mixed hard-and soft-modelling approach to study and monitor enzymatic systems in biological fluids. Anal. Chim. Acta 567, 245, 2006.
  • 27. AZZOUZ T., TAULER R. Application of multivariate curve resolution altering least squares (MCR-ALS) to quantitative analysis of pharmaceutical and agricultural samples. Talanta 74, 1201, 2008.
  • 28. BEEBE K.R., PELL R.J., SEASHOLTZ M.B. Chemometrics: A Practical Guide John Willey& Sons, New York, 1998.
  • 29. MAZERSKI J. "Chemometrics analysis of absorption spectra." In Proceedings of II Conference Chemometrics, Methods and Applications, Zakopane, October 2003, pp. 100-127, 2003.
  • 30. GEMPERLINE P. Ed. Practical Guide to Chemometrics. Taylor&Francis Group, 2006.
  • 31. ZAFIROU O.C., JOUSSOT-DUBIEN J., ZEPP R.G., ZIKA R.G., Photochemistry of natural waters. Environ. Sci. Technol. 18, 358A, 1984.
  • 32. SOUTHWORTH B.A, VOELKER B.M. Hydroxyl Radical Production via the Photo-Fenton Reaction in the Presence of Fulvic Acid. Environ. Sci. Technol. 37, 1130, 2003.
  • 33. NAKATANI N., UEDA M., SHINDO H., TAKEDA K, SAKUGAWA H. Contribution of the Photo-Fenton Reaction to Hydroxyl Radical Formation Rates in River and Rain Water Samples Anal. Sci., 23, 1137, 2007.
  • 34. VERMLYEA A.W., VOELKER B.M. Photo-Fenton Reaction at Near Neutral pH Environ. Sci. Technol. 43, 6927, 2009.
  • 35. DOJLIDO J.R. Surface water Chemistry, Wyd. Ekonomia i Środowisko, Białystok 1995 [In Polish],
  • 36. DOJLIDO J.R. Physicochemical examination of water and sewage. Wyd. Arkady, Warszawa 1999 [In Polish],
Typ dokumentu
Identyfikator YADDA
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.