Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2010 | 60 | 1 |
Tytuł artykułu

p-Aminobenzoic acid (PABA) changes folate content in cell biomass of Saccharomyces cerevisiae

Treść / Zawartość
Warianty tytułu
Języki publikacji
The folic acid intake is definitely lower than the recommended dietary allowance. This study shows the possibility of enhancing the synthesis of folates by the baker’s yeast. p-Aminobenzoic acid (PABA) addition to the examined culture media at doses of 5–25 μg/cm3 increases the content of folates, which in turn depends on the strain and PABA dose. The culturing of yeast with PABA might form the basis for the production of bakery products that are rich in folates and, consequently, might constitute an additional folate source in the everyday diet.
Słowa kluczowe
Opis fizyczny
  • Department of Biotechnology, Microbiology and Food Evaluation, Warsaw University of Life Science, Nowoursynowska Str.166, 02-776 Warsaw, Poland
  • 1. Blakely R.L., The Biochemistry of Folic Acid and Related Pteridines. 1969, North-Holland Publishing, Amsterdam, pp. 76–97.
  • 2. Brouwer I.A., Van Dusseldorp M., Thomas C.M.G., Duran M., Hautvast J.G.A.J., Eskes T.K.A.B., Steegers-Theuinssen R.P.M., Low-dose folic acid supplementation decreases plasma homocysteine concentrations: a randomized trial. Am. J. Clin. Nutr., 1999, 69, 99–104.
  • 3. De Bree A., Van Dusseldro M., Brouwer J.A., van het Hof K.F., Steegers-Theunissen R.P., Folate intake in Europe: recommended, actual and desired intake. Eur. J. Clin. Nutr., 1997, 51, 643–660.
  • 4. Buttriss J., Strategies to increase folate/folic acid intake in women: an overview. British Nutrition Foundation Nutr. Bull., 2004, 29, 234–244.
  • 5. George L., Mills J.L., Johansson A.L.V., Nordmark A., Olander B., Granath F., Cnattingius S., Plasma folate levels and risk of spontaneous abortion. JAMA, 2002, 288, 1867–1873.
  • 6. Graham I.M., Daly L.E., Refsum H.M., Robinson K., Brattstrom L.E., Ueland P.M.,Palma-Reis R.J., Boers G.H.J., Sheahn R.G., Israelsson B., Uiterwaal C.S., Meleady R., McMaster D., Verhoef P., Witteman J., Rubba P., Bellet H., Wautrecht J.C., de Valk H., Sales Luis A.C., Parrot-Roulaud F.M., Tan K.S., Higgins I., Garcon D., Medrano M.J., Candito M., Evans A.E., Andria G., Plasma homocysteine as a risk factor for vascular disease. JAMA, 1997, 277, 1775–1781.
  • 7. Goli D.P., Vanderslice J.T., Investigation of the conjugase treatment procedure in the microbiological assay of folate. Food Chem., 1992, 43, 57–64.
  • 8. Gregory I.J.F., Foster K., Tyler H., The dietary and nutritional survey of British adults. 1990, HMSO, London, pp. 13–16.
  • 9. Hjortmo S., Patring J., Jastrebova J., Andlid T., Inherent biodiversity of folate content and composition in yeasts. Trends Food Sci. Techol., 2005, 16, 311–316.
  • 10. Hoffbrand A.V., Weir D.G., Historical review. The history of folic acid. Brit. J. Haematol., 2001, 113, 579–589.
  • 11. Iwatani Y., Arcot J., Shrestha A.K., Determination of folate contents in some Australian vegetables. J. Food Comp. Anal., 2003, 16, 37–48.
  • 12. Jägerstad M., Piironen V., Walker C., Ros G., Carnovale E., Holasova M., Nau H., Increasing natural food folates through bioprocessing and biotechnology. Trends Food Sci. Technol., 2005, 16, 298–306.
  • 13. Molloy A.M., The role of folic acid in the prevention of neural tube defects. Trends Food Sci. Technol., 2005, 16, 241–245.
  • 14. Moreiras G.V., Gonzalez M.P., Alonso-Aperte E., Impaired methionine and folate metabolism in colorectal carcinogenesis. Trends Food Sci. Technol., 2005, 16, 282–288.
  • 15. Puwastien P., Pinprapai N., Judprasong K., Tamura T., International inter-laboratory analyses of food folate. J. Food Comp. Anal., 2005, 18, 387–397.
  • 16. Report of Food and Nutrition Board Institute of Medicine. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, panthothetic acid, biotin and choline. 1998, National Academy Press. Washington.
  • 17. Rimm E.B., Willet W.C., Hu F.B., Sampson L., Colditz G.A., Manson J., Hennekens C., Stampfer M.J., Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart diseases among women. JAMA, 1998, 279, 359–364.
  • 18. Seyoum E., Selhub J., Properties of food folates determined by stability and susceptibility to intestinal pteroylpolyglutamate hydrolase action. J. Nutr., 1998, 128, 1956–1960.
  • 19. Seshadri S., Beiser A., Selhub J., Jacques P.F., Rosenberg I.H., D’Agostino R.B., Wilson P.W.F., Wolf P.A., Plasma homocysteine as a risk factor for dementia and Alzheimer’s disease. New Engl. J. Med., 2002, 346, 476–483.
  • 20. Tamura T., Microbiological assay of folates. Folic Acid Metabolism in Health and Disease, 1990, vol. 13. Wiley-Liss. New York. pp. 121–137.
  • 21. Temple C. Jr., Montgomery J.A., Chemical and physical properties of folic acid and reduced derivatives. Blakely R.L., Benkovic, S.J., 1984, in: Folates and Pteridines, 1, Wiley (Interscience), New York, pp.60–120.
  • 22. Vahteristo L.T., Ollilainen V., Koivistoinen P.E., Varo P., Improvements in the analysis of reduced folate monoglutamates in food by high-performance liquid chromatography. J. Agric. Food Chem., 1996, 44, 447–482.
  • 23. Verduyn C., Postma E., Scheffers W.A., Van Dijken J.P., Effect of benzoic acid on metabolic fluxes in yeast: a continuous-culture study on the regulation of respiration and alcoholic fermentation. Yeast, 1992, 8, 501–517.
  • 24. Vollset S.F., Refsum H., Irgens L.M. Plasma total homocysteine pregnancy complications and adverse pregnancy outcomes: the Hordaland Homocysteina Study. Am. J. Clin. Nutr., 2000, 71, 926–928.
Rekord w opracowaniu
Typ dokumentu
Identyfikator YADDA
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.