Dietary supplementation with Aloe vera polysaccharide enhances the growth performance and immune function of weaned piglets

• Autorzy: Qiao J. , Li H. H. , Zheng C. J. , Feng Z. Y. , Wang W.
• Języki publikacji: EN

Abstrakty

EN

This study was conducted to investigate the effects of crude Aloe vera polysaccharide (AVP) on the growth performance and immune function of weaned piglets. A total of 200 (Landrace Yorkshire × Duroc) weaned pigs at 21 d with initial 8.88 ± 0.49 kg body weight (BW) were allotted to one of four dietary treatments in a randomized complete block design according to their sex and BW (5 replicates with 10 pigs per pen, 5 gilts and 5 barrows). Dietary treatments included one basal diet, and three diets with AVP supplementation (0.05%, 0.1%, or 0.2%). Average daily gain (ADG), average daily feed intake (ADFI), and feed:gain (F:G) ratios were calculated at the end of the experiment. Separated serum samples from each treatment were assayed at the end of the experiment for the concentrations of cytokines and the blocking rate of antibodies against classical swine fever virus (CSFV). Supplementation of AVP at 0.1% improved (P < 0.05) ADG compared with the control group. No significant differences in ADFI or F:G were observed between AVP-treated and untreated control piglets. All AVP-treated pigs had a significantly lower incidence of diarrhoea (P < 0.05) when compared with control pigs. Feeding AVP resulted in increasing (P < 0.01) IL-2 and IFN-γ (at 0.1% and 0.2%) and IL-4 (at 0.05%, 0.1% and 0.2%), and in no significant changing of IL-10 (P > 0.05). Supplementation of AVP at 0.05%, 0.1% and 0.2% increased (P < 0.01) the blocking rate of antibodies against CSFV. These results indicate that dietary supplementation with dietary AVP enhanced growth performance in weaned piglets by improving immune function, decreasing the incidence of diarrhoea

Słowa kluczowe

EN

animal nutrition; dietary supplementation; Aloe vera; polysaccharide; growth performance; immune function; cytokine; weaned piglet; piglet

• Wydawca: -
• Czasopismo: Journal of Animal and Feed Sciences
• Rocznik: 2013
• Tom: 22
• Numer: 4
• Opis fizyczny: p.329-334,ref.

Twórcy

autor

Qiao J.

• Tianjin Institute of Animal Husbandry and Veterinary Science, XiQing District Jinjing Road 17 km, Tianjin, 300384, P.R.China
• National Key Laboratory of Animal Nutrition, China Agricultural University, No.2 Yuanmingyuan West Road, Beijing, 100193, P.R.China

autor

Li H. H.

• Tianjin Institute of Animal Husbandry and Veterinary Science, XiQing District Jinjing Road 17 km, Tianjin, 300384, P.R.China

autor

Zheng C. J.

• Tianjin Institute of Animal Husbandry and Veterinary Science, XiQing District Jinjing Road 17 km, Tianjin, 300384, P.R.China

autor

Feng Z. Y.

• National Key Laboratory of Animal Nutrition, China Agricultural University, No.2 Yuanmingyuan West Road, Beijing, 100193, P.R.China
• National Feed Engineering Technology Research Center Beijing, No.2 Yuanmingyuan West Road, Beijing, 100193, P.R.China

autor

Wang W.

• Tianjin Institute of Animal Husbandry and Veterinary Science, XiQing District Jinjing Road 17 km, Tianjin, 300384, P.R.China

Bibliografia

• Chen W., 2008. Drug absorption enhancing properties of Aloe vera across the intestinal epithelium. D. Tech. Thesis, Tshwane University of Technology, South Africa
• Chow J.T.-N., Williamson D.A., Yates K,M,, Goux W.J., 2005. Chemical characterisation of the immunomodulating polysaccharide of Aloe vera L. Carbohydr. Res., 340, 1131–1142
• Dagne E., Bisrat D., Viljoen A., Van Wyk B.E., 2000. Chemistry of Aloe species. Curr. Org. Chem. 4, 1055–1078
• Dai B.S., Jiang L., Chen S.X., 2007. Effects of medicinal herb and polysaccharide from Aloe on gut microflora, immune function and growth performance in broiler (in Chinese). China Poultry 29, 21–24
• Hamman J.H., 2008. Composition and applications of aloe vera leaf Gel. Molecules 13, 1599–1616
• Huang C.H. Qiao S.Y., Li D.F., Piao X.S., Ren J.P., 2004. Effects of lactobacilli on the performance, diarrhoea incidence, VFA concentration and gastrointestinal microbial flora of weaning pigs. Asian-Austr. J. Anim. Sci. 17, 401–409
• Im S.A., Oh S.T., Song S., Kim M.R., Kim D.S., Woo S.S., Jo T.H., Park Y.I., Lee C.K., 2005. Identification of optimal molecular size of modified Aloe polysaccharides with maximum immunomodulatory activity. Int. Immunopharmacol. 5, 271–279
• Li L.L., Yin F.G., Zhang B., Peng H.Z., Li F.N., Zhu N.S., Hou D.X., Yin Y.L., Luo J.J., Tang Z.R., Liu G., 2011. Dietary supplementation with Atractylodes Macrophala Koidz polysaccharides ameliorate metabolic status and improve immune function in early-weaned pigs. Livest. Sci. 142, 33–41
• Marshall G.D., Gibbons A.S., Parnell L.S., 1993. Human cytokines induced by acemannan. J. Allergy Clin. Immunol. 91, 295
• Ni Y., Turner D., Yates K.M., Tizard I., 2004. Isolation and characterisation of structural components of Aloe vera L. leaf pulp. Int. Immunopharmacol. 4, 1745–1755
• NRC, 1998. Nutrient Requirements of Swine. 10th revised Edition. National Academy Press. Washington, DC
• Peng S.Y., Norman J., Curtin G., Corrier D., McDaniel H.R., Busbee D., 1991. Decreased mortality of Norman murine sarcoma in mice treated with the immunomodulator, Acemannan Mol. Biother. 3, 79–87
• Pugh N., Ross S.A., Eisohly M.A., Pasco D.S., 2001. Characterization of Aloeride, a new high-molecular-weight polysaccharide from Aloe vera with potent immunostimulatory activity. J. Agr. Food Chem. 49, 1030–1034
• Qi J.S., Liu Q.Y., Li X.H., Xiong J.L., Zhou A.M., Wei H., 2008. Aloe additives on the performance and meat quality of pigs (in Chinese). Sci. Technol. Inform. 14, 652–652
• Renson P., Le Dimna M., Keranflech A., Cariolet R., Koenen F., Le Potier M. F., 2013. CP7_E2alf oral vaccination confers partial protection against early classical swine fever virus challenge and interferes with pathogeny-related cytokine responses. Vet. Res. 44, 9–19
• Reynolds T., Dweck A.C., 1999. Aloe vera leaf gel: a review update. J. Ethnopharmacol. 68, 3–37
• Šutovská M., 2010. Influence of polysaccharides from Aloe vera (Aloe barbadensis Miller, Liliaceae) on mechanically induced cough in cats. Acta Vet. Brno 79, 51–59
• Talmadge J., Chavez J., Jacobs L., Munger C., Chinnah T., Chow J.T., Williamson D., Yates K., 2004. Fractionation of Aloe vera L. inner gel, purification and molecular profiling of activity. Int. Immunopharmacol. 4, 1757–1773
• t’Hart L.A., van den Berg A.J., Kuis L., van Dijk H., Labadie R.P., 1989. An anti-complementary polysaccharide with immunological adjuvant activity from the leaf parenchyma gel of Aloe vera. Planta Med. 55, 509–512
• Yin F.G., Yin Y.L., Kong X.F., Liu Y.L., He Q.H., Li T.J., Huang R.L., Hou Y.Q., Shu X.G., Tan L.X., Chen L.X., Gong J.H., Kim S.W.,
• Wu G.Y., 2008. Dietary supplementation with Acanthopanax senticosus extract modulates gut microflora in weaned pigles. Asian-Austr. J. Anim. Sci. 21, 1330–1338
• Yu Z.H., Che J., Ma X., He J.M., 2009. Effect of Aloe vera polysaccharides on immunity and antioxidant activities in oral ulcer animal models. Carbohyd. Polym. 75, 307–311
• Yuan S.L., Piao. X.S., Li D.F., Kim S.W., Lee H.S., Guo P.F., 2006. Effects of dietary Astragalus polysaccharide on growth performance and immune function in weaned pigs. Anim. Sci. 82, 501–507
• Yusuf S., Agunu A., Diana M., 2004. The effect of Aloe vera A. berger (Liliaceae) on gastric acid secretion and acute gastric mucosal injury in rats. J. Ethnopharmacol. 93, 33–37
• Zhang L., Tizard I.R., 1996. Activation of a mouse macrophage cell line by acemannan: The major carbohydrate fraction from Aloe vera. Immunopharmacology 35, 119–128