Cardiopathology in acute African Swine Fever

• Autorzy: Semerjyan A.B. , Tatoyan M.R. , Karalyan N.Y. , Nersisyan N.H. , Hakobyan L.H. , Arzumanyan H.H. , Karalyan Z.A.
• Języki publikacji: EN

Abstrakty

EN

The present study describes the gross, histopathologic lesions of the heart arising in pigs infected with acute African Swine Fever (ASF) and their biochemical profile. Ten pigs were infected by intramuscular injection of ASF virus (Georgia 2007). Selected heart samples were submitted for histopathological examination and Hematoxylin-Basic Fuchsin-Picric Acid (HBFP) staining. Enzymatic abnormalities were evaluated by measurement of main cardiac markers, whose activity increased during the early stage of infection, with histopathological changes occurring later. Minor myocardial haemorrhages were first observed at four days post infection (dpi), and were noted in all pigs by six dpi. Early vascular response to infection was manifested as increased capillary permeability leading to diapedesis and the retention of blood cells in myocardial tissue. The terminal stage of the disease was characterised by massive haemorrhages caused by the rupture of large vessels. Substantial ischemic areas were detected by HBFP staining at the terminal stages of ASF.

• Wydawca: -
• Czasopismo: Annals of Parasitology
• Rocznik: 2018
• Tom: 64
• Numer: 3
• Opis fizyczny: p.253-258,fig.,ref.

Twórcy

autor

Semerjyan A.B.

• Department of Medical Biology and Parasitology, Yerevan State Medical University, 2 Koryun St., Yerevan 0025, Armenia

autor

Tatoyan M.R.

• Department of Cytology, Histology and Embryology, Yerevan State Medical University, 2 Koryun St., Yerevan 0025, Armenia

autor

Karalyan N.Y.

• Department of Pathological Anatomy and Clinical Morphology, Yerevan State Medical University, 2 Koryun St., Yerevan 0025, Armenia

autor

Nersisyan N.H.

• Laboratory of Cell Biology and Virology, Institute of Molecular Biology of NAS, 7 Hasratyan St., Yerevan 0014, Armenia

autor

Hakobyan L.H.

• Laboratory of Cell Biology and Virology, Institute of Molecular Biology of NAS, 7 Hasratyan St., Yerevan 0014, Armenia

autor

Arzumanyan H.H.

• Laboratory of Cell Biology and Virology, Institute of Molecular Biology of NAS, 7 Hasratyan St., Yerevan 0014, Armenia

autor

Karalyan Z.A.

• Department of Medical Biology and Parasitology, Yerevan State Medical University, 2 Koryun St., Yerevan 0025, Armenia
• Laboratory of Cell Biology and Virology, Institute of Molecular Biology of NAS, 7 Hasratyan St., Yerevan 0014, Armenia
• Department of Bioengineering, Bioinformatics and Molecular Biology, Russian-Armenian (Slavonic) University, 123 Hovsep Emin St., Yerevan 0051, Armenia

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Identyfikatory

DOI

10.17420/ap6403.161