Is the prostaglandin E2 responsible for pyrogen fever centrally or peripherally derived?

• Autorzy: Milton A.S.
• Języki publikacji: EN

Słowa kluczowe

EN

prostaglandin E2; thermoregulation; brain; heat loss; body temperature; pyrogen; fever

• Wydawca: -
• Czasopismo: Acta Physiologica Polonica
• Rocznik: 1990
• Tom: 41
• Numer: 1-3
• Opis fizyczny: p.9-17,fig.,ref.

Twórcy

autor

Milton A.S.

• Department of Pharmacology, University of Aberdeen, Aberdeen, Scotland

Bibliografia

• 1. Abul H., Davidson J., Milton A. S., Rotondo D. (1987a). Dexamethasone pretreated is antipyretic towards polyinosinic.polycytidylic acid, lipopolysaccharide and interleukin 1 endogenous pyrogen. Naunyn, Schmicdeberg’s Arch. Pharmacol., 335, 305-309.
• 2. Abul H., Davidson J., Milton A. S., Rotondo D. (1987b). The effect of pyrogens and antipyretics on blood prostaglandin E₂ levels in the rabbit. J. Physiol. (London), 391, 94P.
• 3. Abul H., Milton A. S. (1988). The effects of dexamethasone on prostaglandin E₂ release into CSF during fever and on the pyrogen-stimulated release of prostaglandin E₂ from rabbit monocytes. J. Physiol. (London) (in press).
• 4. Feldberg W„ Gupta K. P., Milton A. S., Wendlandt S. (1973). Effect of pyrogen and antipyretics on prostaglandin activity in cisternal CSF of unanaesthetized cats. J. Physiol. (London), 234, 279- 303.
• 5. Harvey C. A., Milton A. S„ Straughan D. W. (1975). Prostaglandin E levels in cerebrospinal fluid of rabbits and the effects of bacterial pyrogen and antipyretic drugs. J. Physiol. (London), 248, 26- 27P.
• 6. Kozak W., Milton A. S., Abul H., Davidson J., Rotondo D. Lipopolysaccharide, muramyl dipeptide and polyinosinic: polycytidylic acid induce the accumulation of inositol phosphates in leukocytes. Cellular Signalling (in press).
• 7. Kozak W., Milton A. S., Rotondo D. (1988). Pyrogenic immunomodulators increase the accumulation of inositol phosphates in monocytes. Brit. J. Pharmacol., 94, 337P.
• 8. Milton A. S., Abul H. T., Davidson J., Rotondo D. (1988). Antipyretic mechanism of action of dexamethasone. In: Thermoregulation: Research and Clinical Applications. Eds. Lomax P., Schonbaum E., Karger, Basel.
• 9. Milton A. S., Rotondo D. (1987). The effects of pyrogens on phospholipase A₂ activity in the rabbit. J. Physiol. (London), 391, 95P.
• 10. Rotondo D., Abul H. T., Milton A. S., Davidson J. (1988). Pyrogenic immunomodulators increase the level of prostaglandin E₂ in the blood simultaneously with the onset of fever. Eur. J. Pharmacol., 154, 145-152.